FI87530B - Foerfarande foer framstaellning av streptococcus equi -stammen - Google Patents

Foerfarande foer framstaellning av streptococcus equi -stammen Download PDF

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Publication number
FI87530B
FI87530B FI871060A FI871060A FI87530B FI 87530 B FI87530 B FI 87530B FI 871060 A FI871060 A FI 871060A FI 871060 A FI871060 A FI 871060A FI 87530 B FI87530 B FI 87530B
Authority
FI
Finland
Prior art keywords
equi
strain
avirulent
virulent
infection
Prior art date
Application number
FI871060A
Other languages
English (en)
Finnish (fi)
Other versions
FI871060A0 (fi
FI87530C (sv
FI871060A (fi
Inventor
John F Timoney
Original Assignee
Cornell Res Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Res Foundation Inc filed Critical Cornell Res Foundation Inc
Publication of FI871060A0 publication Critical patent/FI871060A0/fi
Publication of FI871060A publication Critical patent/FI871060A/fi
Application granted granted Critical
Publication of FI87530B publication Critical patent/FI87530B/fi
Publication of FI87530C publication Critical patent/FI87530C/sv

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/829Bacterial vaccine for equine species, e.g. horses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/885Streptococcus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Claims (4)

1. Förfarande för framställning av en sädan stam av Streptococcus equi som är avirulent för hästar, kannetecknat av att det omfattar följande steg: 1. man utsätter en virulent stam av S. equi CF32 (ATCC 53185) för mutationsbildning vid behandling med kemisk mutagen eller strälning, och 2. den resulterande avirulenta och skyddande stammen se-lekteras vid undersökning av icke-inkapslade kolonier och med selektering av stammen, som är avirulent, innehäller M-proteinfragment, vars molekylvikt är 41 000 och som medför S. equi -antikroppsförsvar.
2. Förfarande enligt patentkravet 1, kännetecknat av att den virulenta stammen av Streptococcus equi muteras vid kemisk induserad mutagenes eller vid strälninginduserat muta-genes.
3. Förfarande enligt patentkravet 2, kännetecknat av att den virulenta stammen av S. equi muteras vid behandling av nitrosoguanin och den avirulenta och skyddande stammen väljs ut vid undersökning av icke-inkapslade kolonier och selektering av en stam, som är avirulent pä möss efter intraperi-toneal inokulering, skyddar möss mot den virulenta stammen och som innehäller M-proteinfragment, vars molekylvikt är cirka 41 000 och som medför S. equi -antikroppsreaktion.
4. Förfarande enligt patentkravet 3, kännetecknat av att den avirulenta stammen av S. equi är Streptococcus equi 709-27, som deponerats tili ATCC med nummer 53186.
FI871060A 1985-07-12 1987-03-11 Förfarande för framställning av Streptococcus equi -stammen FI87530C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75461385A 1985-07-12 1985-07-12
US75461385 1985-07-12
US8601460 1986-07-14
PCT/US1986/001460 WO1987000436A1 (en) 1985-07-12 1986-07-14 The protection of equines against streptococcus equi

Publications (4)

Publication Number Publication Date
FI871060A0 FI871060A0 (fi) 1987-03-11
FI871060A FI871060A (fi) 1987-03-11
FI87530B true FI87530B (fi) 1992-10-15
FI87530C FI87530C (sv) 1993-01-25

Family

ID=25035573

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871060A FI87530C (sv) 1985-07-12 1987-03-11 Förfarande för framställning av Streptococcus equi -stammen

Country Status (18)

Country Link
US (1) US5183659A (sv)
EP (1) EP0230456B1 (sv)
JP (1) JPH0816064B2 (sv)
AR (1) AR241545A1 (sv)
AT (1) ATE71532T1 (sv)
AU (1) AU604645B2 (sv)
CA (1) CA1281287C (sv)
DE (1) DE3683478D1 (sv)
DK (1) DK167599B1 (sv)
ES (1) ES2000491A6 (sv)
FI (1) FI87530C (sv)
GR (1) GR861795B (sv)
IE (1) IE58964B1 (sv)
NO (1) NO169997C (sv)
NZ (1) NZ216796A (sv)
PT (1) PT82971B (sv)
WO (1) WO1987000436A1 (sv)
ZA (1) ZA865156B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2523883Y2 (ja) * 1992-02-24 1997-01-29 株式会社三協精機製作所 プーリ付調速器
ZA97452B (en) 1996-01-25 1997-08-15 Trinity College Dublin Streptococcus equi vaccine.
US6086894A (en) * 1996-06-27 2000-07-11 Virginia Tech Intellectual Properties, Inc. Recombinant vaccine for diseases caused by encapsulated organisms
EP0993469A1 (en) 1997-06-24 2000-04-19 John F. Timoney COMPOUNDS ENCODING THE PROTECTIVE M-LIKE PROTEIN OF $i(STREPTOCOCCUS EQUI) AND ASSAYS THEREFOR
CA2243730C (en) * 1997-07-29 2009-12-22 Akzo Nobel N.V. Streptococcus equi vaccine
US20070059327A2 (en) * 1998-01-15 2007-03-15 Wyeth Streptococcus equi compositions and methods of use
DE60007668T2 (de) * 1999-01-26 2004-12-02 Akzo Nobel N.V. Verwendung lebender abgeschwächter Bakterien zur Herstellung eines submukosalen Impstoffes
CA2501621C (en) 2002-10-11 2012-01-24 Bengt Guss Immunization of non-human mammals against streptococcus equi
US20110020403A1 (en) 2007-12-13 2011-01-27 Bengt Guss immunizing composition
EP2590994B1 (en) 2010-05-26 2016-11-02 Intervacc AB Vaccine against streptococcal infections based on recombinant proteins
EP3057613A1 (en) 2013-10-17 2016-08-24 Zoetis Services LLC Methods and compositions for treatment of s. equi infection
KR101694676B1 (ko) * 2015-12-10 2017-01-10 우진 비앤지 주식회사 말 선역 질병원인 국내 분리 스트렙토코커스 이콰이 균주 및 이를 포함하는 백신

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3793150A (en) * 1971-01-20 1974-02-19 Richardson Merrell Inc Equine strangles vaccine and method of preparing and using the same
US3852420A (en) * 1971-01-20 1974-12-03 Richardson Merrell Inc Equine strangles vaccine and method of preparing and using the same
IL52815A (en) * 1977-08-24 1983-03-31 Israel State Fowl cholera vaccine and process for producing an attenuated non-virulent strain of pasteurella multocida
JPS60251898A (ja) * 1984-05-25 1985-12-12 Shiseido Co Ltd 醗酵法によるヒアルロン酸の製造方法
US4582798A (en) * 1984-11-23 1986-04-15 Miles Laboratories, Inc. Preparation and use of enzyme-detergent extracted Streptococcus equi vaccine

Also Published As

Publication number Publication date
FI871060A0 (fi) 1987-03-11
FI87530C (sv) 1993-01-25
WO1987000436A1 (en) 1987-01-29
ES2000491A6 (es) 1988-03-01
AR241545A1 (es) 1992-08-31
FI871060A (fi) 1987-03-11
ZA865156B (en) 1987-05-27
AU6149686A (en) 1987-02-10
IE861852L (en) 1987-01-11
CA1281287C (en) 1991-03-12
NO871012L (no) 1987-03-11
NO169997C (no) 1992-09-02
PT82971A (pt) 1986-08-01
JPS63500596A (ja) 1988-03-03
DK167599B1 (da) 1993-11-29
AU604645B2 (en) 1991-01-03
NZ216796A (en) 1991-11-26
DK125887D0 (da) 1987-03-11
GR861795B (en) 1986-11-11
NO169997B (no) 1992-05-25
DK125887A (da) 1987-03-11
PT82971B (pt) 1988-07-01
ATE71532T1 (de) 1992-02-15
IE58964B1 (en) 1993-12-01
EP0230456A4 (en) 1987-10-27
DE3683478D1 (de) 1992-02-27
JPH0816064B2 (ja) 1996-02-21
EP0230456B1 (en) 1992-01-15
EP0230456A1 (en) 1987-08-05
NO871012D0 (no) 1987-03-11
US5183659A (en) 1993-02-02

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FG Patent granted

Owner name: CORNELL RESEARCH FOUNDATION INC.

MA Patent expired