FI873363A0 - Foerfarande foer framstaellning av laekemedel med antitumoeraktivitet. - Google Patents

Foerfarande foer framstaellning av laekemedel med antitumoeraktivitet.

Info

Publication number
FI873363A0
FI873363A0 FI873363A FI873363A FI873363A0 FI 873363 A0 FI873363 A0 FI 873363A0 FI 873363 A FI873363 A FI 873363A FI 873363 A FI873363 A FI 873363A FI 873363 A0 FI873363 A0 FI 873363A0
Authority
FI
Finland
Prior art keywords
antitumoeraktivitet
laekemedel
med
foerfarande foer
foer framstaellning
Prior art date
Application number
FI873363A
Other languages
English (en)
Finnish (fi)
Other versions
FI873363A7 (fi
FI873363L (fi
Inventor
Hansjoerg Eibl
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Publication of FI873363A7 publication Critical patent/FI873363A7/fi
Publication of FI873363L publication Critical patent/FI873363L/fi
Publication of FI873363A0 publication Critical patent/FI873363A0/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI873363A 1985-12-04 1986-12-04 Foerfarande foer framstaellning av laekemedel med antitumoeraktivitet. FI873363A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3542893 1985-12-04
DE3606631 1986-02-28
PCT/EP1986/000705 WO1987003480A2 (en) 1985-12-04 1986-12-04 Medicament with anti-tumoral action containing hexadecylphosphocholine

Publications (3)

Publication Number Publication Date
FI873363A7 FI873363A7 (fi) 1987-08-03
FI873363L FI873363L (fi) 1987-08-03
FI873363A0 true FI873363A0 (fi) 1987-08-03

Family

ID=25838509

Family Applications (2)

Application Number Title Priority Date Filing Date
FI873363A FI873363A0 (fi) 1985-12-04 1986-12-04 Foerfarande foer framstaellning av laekemedel med antitumoeraktivitet.
FI873364A FI873364A7 (fi) 1985-12-04 1987-08-03 Foerfarande foer framstaellning av ett sytotoxiskt laekemedel.

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI873364A FI873364A7 (fi) 1985-12-04 1987-08-03 Foerfarande foer framstaellning av ett sytotoxiskt laekemedel.

Country Status (15)

Country Link
US (2) US4837023A (enEXAMPLES)
EP (4) EP0230575A3 (enEXAMPLES)
JP (2) JPH0637393B2 (enEXAMPLES)
AT (2) ATE75608T1 (enEXAMPLES)
CA (2) CA1338627C (enEXAMPLES)
DE (4) DE3679908D1 (enEXAMPLES)
DK (2) DK172954B1 (enEXAMPLES)
ES (2) ES2038215T3 (enEXAMPLES)
FI (2) FI873363A0 (enEXAMPLES)
GR (2) GR3002487T3 (enEXAMPLES)
HU (2) HU203201B (enEXAMPLES)
IE (2) IE59777B1 (enEXAMPLES)
NO (2) NO174877C (enEXAMPLES)
PT (2) PT83873B (enEXAMPLES)
WO (2) WO1987003480A2 (enEXAMPLES)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916884A (en) * 1985-12-04 1999-06-29 Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften Compositions containing a mixture of phosphorus compounds and alkylglycerols
CA2001401A1 (en) * 1988-10-25 1990-04-25 Claude Piantadosi Quaternary amine containing ether or ester lipid derivatives and therapeutic compositions
EP0412941B1 (en) * 1989-08-10 1996-05-15 Sandoz Ltd. Phospholipids for the treatment of multiple sclerosis
US5182271A (en) * 1989-08-10 1993-01-26 Sandoz Ltd. Thioether, keto-ester and alkyl phospholipids useful in treating multiple sclerosis
US5290769A (en) * 1989-09-27 1994-03-01 Asta Pharma Aktiengesellschaft Use of hexadecylphosphocholine for the treatment of psoriasis
EP0916343A1 (de) * 1989-09-27 1999-05-19 ASTA Medica Aktiengesellschaft Verwendung von Alkylphosphorsäure-Verbindungen zur Bekämpfung von Psoriasis-Erkrankungen
DE4111105A1 (de) * 1991-04-05 1992-10-08 Max Planck Gesellschaft Neue erucyl-, brassidyl- und nervonylderivate
US5506217A (en) * 1991-04-25 1996-04-09 The University Of British Columbia Phosphonates as anti-cancer agents
US5369097A (en) * 1991-04-25 1994-11-29 The University Of British Columbia Phosphonates as anti-cancer agents
ATE158295T1 (de) * 1991-07-04 1997-10-15 Asta Medica Ag Verfahren zur herstellung von alkylphosphocholinen und reinherstellung derselben
DE4132344A1 (de) * 1991-09-27 1993-04-01 Max Planck Gesellschaft Verfahren zur herstellung eines arzneimittels zur oralen oder topischen verabreichung bei der behandlung von leishmaniasis
US6254879B1 (en) 1991-09-27 2001-07-03 Max-Planck-Gessellschaft zun Förderung der Wissenschaften e.V. Methods of treating protozoal diseases
US5298655A (en) * 1991-09-27 1994-03-29 Merck & Co., Inc. Farnesyl pyrophosphate analogs
DE4222910A1 (de) * 1992-07-11 1994-01-13 Asta Medica Ag Neue Phospholipidderivate
US6172050B1 (en) 1992-07-11 2001-01-09 Asta Medica Aktiengesellschaft Phospholipid derivatives
DE4235911A1 (de) * 1992-10-23 1994-04-28 Asta Medica Ag Stabilisierte Hexadecylphosphocholinlösungen in Glycerinalkylethern
ATE226437T1 (de) * 1993-06-10 2002-11-15 Univ Wake Forest (phospho)lipide zum bekämpfen einer hepatitis b- infektion
US6551623B1 (en) 1993-09-09 2003-04-22 Lorus Therapeutics Inc. Immunomodulating compositions from bile
CA2171281C (en) 1993-09-09 1998-12-29 Romeo Rang Immunomodulating compositions from bile
DE69535758D1 (de) 1994-08-29 2008-07-03 Univ Wake Forest Lipid-analoge zur behandlung von viralen infektionen
US7135584B2 (en) * 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
US5574025A (en) * 1994-10-26 1996-11-12 Merck & Co., Inc. Inhibitors of prenyl-protein transferases
AU1573495A (en) * 1995-02-10 1996-08-27 University Of British Columbia, The {4-hexadecyl-3-methoxy-butyl} phosphonic acid and its protienconjugates useful as anti-cancer agents
WO1996028175A1 (en) 1995-03-16 1996-09-19 Imutec Pharma Inc. Immunomodulating compositions from bile for the treatment of immune system disorders
KR100499190B1 (ko) * 1996-03-29 2006-04-17 교와 핫꼬 고교 가부시끼가이샤 육모제
US20040101569A1 (en) * 1996-05-16 2004-05-27 Lorus Therapeutics Inc. Immunomodulating compositions from bile
US6121245A (en) * 1997-01-29 2000-09-19 Firshein; Richard N. Method of treating cancer using alkylglycerols in conjunction with chemotherapy
SE9701912D0 (sv) * 1997-05-22 1997-05-22 Interhealth Ab Pharmaceutical composition and use thereof
US7582678B2 (en) * 1997-07-09 2009-09-01 D-Pharm Limited Use of branched-chain fatty acids and derivatives thereof for the treatment of pain
AU756805B2 (en) * 1998-01-22 2003-01-23 Zentaris Gmbh Solid pharmaceutical compositions containing miltefosine for oral administration in the treatment of leishmaniasis
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
IL137672A0 (en) 2000-08-03 2001-10-31 Dpharm Ltd Derivatives of branched-chain lipophilic molecules and uses thereof
US7309696B2 (en) 2000-10-19 2007-12-18 Wake Forest University Compositions and methods for targeting cancer cells
WO2002096826A2 (en) * 2001-05-29 2002-12-05 Koninklijke Philips Electronics N.V. Metal-ceramic bond
JP4714413B2 (ja) * 2001-08-31 2011-06-29 トムソン ライセンシング オーディオビジュアルストリームのためのシーケンスカウンタ
AU2002346284A1 (en) * 2002-04-26 2003-11-10 Rudolf Perl Pharmaceutical compositions of phospholipid derivatives
US20050187191A1 (en) * 2004-02-20 2005-08-25 Kucera Louis S. Methods and compositions for the treatment of respiratory syncytial virus
EP1962862B1 (en) 2005-12-19 2013-09-04 Æterna Zentaris GmbH Alkyl phospholipid derivatives with reduced cytotoxicity and uses therof
EP2120873B1 (en) * 2006-12-20 2012-06-27 Alphaptose Gmbh Topical dosage form comprising tri-substituted glycerol compounds
JP2011057647A (ja) * 2009-09-14 2011-03-24 Adeka Corp 化粧料
CN111298120A (zh) 2011-06-24 2020-06-19 格里生物公司 炎性病症的预防和治疗
CN102491994B (zh) * 2011-12-07 2014-10-15 宁波九胜创新医药科技有限公司 一种胆碱磷酸烷基酯的制备方法
CN107206086B (zh) * 2014-12-09 2022-03-18 Gri生物有限公司 炎性病况的预防和治疗

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3225227A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Derivate des n.n-bis-(2-chlor-aethyl)-phosphorsaeureamids
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
US4690935A (en) * 1983-03-31 1987-09-01 Wayne State University Inhibition of tumor growth and metastasis with calcium channel blocker compounds
JPS60184092A (ja) 1984-03-01 1985-09-19 Kao Corp リン酸エステルおよびその製法

Also Published As

Publication number Publication date
HUT44441A (en) 1988-03-28
DK393187D0 (da) 1987-07-28
DK398587A (da) 1987-07-30
NO873244D0 (no) 1987-08-03
IE863177L (en) 1987-06-04
CA1338627C (en) 1996-10-01
FI873364A0 (fi) 1987-08-03
GR3005168T3 (enEXAMPLES) 1993-05-24
EP0230575A3 (de) 1987-12-02
GR3002487T3 (en) 1992-12-30
ATE75608T1 (de) 1992-05-15
EP0248047A1 (de) 1987-12-09
WO1987003480A3 (en) 1988-02-25
DE3679908D1 (de) 1991-07-25
PT83873A (de) 1987-01-01
DK172954B1 (da) 1999-10-18
FI873364A7 (fi) 1987-08-03
US4837023A (en) 1989-06-06
US5049552A (en) 1991-09-17
DE3641491A1 (de) 1987-09-17
WO1987003478A2 (en) 1987-06-18
CA1280369C (en) 1991-02-19
NO873243L (no) 1987-10-02
IE863176L (en) 1987-06-04
FI873363A7 (fi) 1987-08-03
NO174877B (no) 1994-04-18
HUT44431A (en) 1988-03-28
HU208143B (en) 1993-08-30
PT83872B (pt) 1989-01-17
EP0248047B1 (de) 1991-06-19
NO873243D0 (no) 1987-08-03
NO175620B (enEXAMPLES) 1994-08-01
IE59777B1 (en) 1994-04-06
EP0248062A1 (de) 1987-12-09
NO174877C (no) 1994-07-27
JPH0637393B2 (ja) 1994-05-18
FI873363L (fi) 1987-08-03
EP0230575A2 (de) 1987-08-05
EP0225608A2 (de) 1987-06-16
JPS63501719A (ja) 1988-07-14
IE59778B1 (en) 1994-04-06
EP0225608A3 (de) 1987-10-28
PT83872A (de) 1987-01-01
ATE64529T1 (de) 1991-07-15
DE3641379A1 (de) 1987-09-03
ES2032755T3 (es) 1993-03-01
NO175620C (no) 1994-11-09
HU203201B (en) 1991-06-28
DK393187A (da) 1987-07-28
DE19375061I2 (de) 2008-11-20
ES2038215T3 (es) 1993-07-16
NO873244L (no) 1987-10-01
DK398587D0 (da) 1987-07-30
EP0248062B1 (de) 1992-05-06
PT83873B (pt) 1989-01-17
JPH0859677A (ja) 1996-03-05
WO1987003480A2 (en) 1987-06-18
WO1987003478A3 (en) 1987-09-24
JP2857084B2 (ja) 1999-02-10

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENS