FI873327A - Nya 3-aryl-3-cykloalkyl-piperidin -2,6-dionderivat. - Google Patents

Nya 3-aryl-3-cykloalkyl-piperidin -2,6-dionderivat. Download PDF

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Publication number
FI873327A
FI873327A FI873327A FI873327A FI873327A FI 873327 A FI873327 A FI 873327A FI 873327 A FI873327 A FI 873327A FI 873327 A FI873327 A FI 873327A FI 873327 A FI873327 A FI 873327A
Authority
FI
Finland
Prior art keywords
radical
cycloalkyl
piperidine
formula
aryl
Prior art date
Application number
FI873327A
Other languages
English (en)
Other versions
FI85016C (fi
FI85016B (fi
FI873327A0 (fi
Inventor
Rolf Wolfgang Hartmann
Christine Batzl
Original Assignee
Asta Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma Ag filed Critical Asta Pharma Ag
Publication of FI873327A0 publication Critical patent/FI873327A0/fi
Publication of FI873327A publication Critical patent/FI873327A/fi
Application granted granted Critical
Publication of FI85016B publication Critical patent/FI85016B/fi
Publication of FI85016C publication Critical patent/FI85016C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms
    • C07D211/88Oxygen atoms attached in positions 2 and 6, e.g. glutarimide

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI873327A 1986-07-31 1987-07-30 Foerfarande foer framstaellning av terapeutiskt anvaendbara 3-(4-aminofenyl)-3-cykloalkylpiperidin -2,6-dionderivat. FI85016C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3625415 1986-07-31
DE3625415 1986-07-31

Publications (4)

Publication Number Publication Date
FI873327A0 FI873327A0 (fi) 1987-07-30
FI873327A true FI873327A (fi) 1988-02-01
FI85016B FI85016B (fi) 1991-11-15
FI85016C FI85016C (fi) 1992-02-25

Family

ID=6306099

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873327A FI85016C (fi) 1986-07-31 1987-07-30 Foerfarande foer framstaellning av terapeutiskt anvaendbara 3-(4-aminofenyl)-3-cykloalkylpiperidin -2,6-dionderivat.

Country Status (16)

Country Link
US (1) US4839370A (fi)
EP (1) EP0258617B1 (fi)
JP (1) JPH0816100B2 (fi)
AT (1) ATE73774T1 (fi)
DD (1) DD264428A5 (fi)
DE (2) DE3724520C2 (fi)
DK (1) DK397487A (fi)
ES (1) ES2039217T3 (fi)
FI (1) FI85016C (fi)
GR (1) GR3004195T3 (fi)
HU (1) HU201740B (fi)
IE (1) IE60589B1 (fi)
IL (1) IL83367A (fi)
NO (1) NO170851C (fi)
PT (1) PT85456B (fi)
ZA (1) ZA875653B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5661014A (en) * 1991-08-22 1997-08-26 Chiroscience Limited Chiral compounds and their resolution synthesis using enantioselective esterases
AU668692B2 (en) * 1991-08-22 1996-05-16 Chiroscience Limited Chiral glutarate esters, their resolution and derived glutarimide compounds
GB9410721D0 (en) * 1994-05-27 1994-07-13 Chiroscience Ltd Chiral compounds and their resolution
CN1307481A (zh) * 1998-04-27 2001-08-08 普雷西斯药品公司 用于治疗热潮红和男子女性型乳房的方法
US6703367B1 (en) * 1999-04-27 2004-03-09 Praecis Pharmaceuticals Inc. Methods for treating hot flashes and gynaecomastia
GB0120147D0 (en) * 2001-08-17 2001-10-10 Metris Therapeutics Ltd Treatment method
US20100087402A1 (en) * 2008-09-29 2010-04-08 Vivus, Inc. Methods and compositions for the treatment of estrogen-dependent hyperproliferative uterine disorders
DE102012002695A1 (de) 2012-02-14 2013-08-14 Wabco Gmbh Verfahren zur Ermittlung einer Notbremssituation eines Fahrzeuges

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA570974A (en) * 1959-02-17 Hoffmann Karl Manufacture of 2:6-dioxo-piperidines
DD16295A (fi) *
AT174909B (de) * 1951-02-13 1953-05-26 Ciba Geigy Verfahren zur Herstellung neuer Dioxopiperidine
GB720198A (en) * 1951-02-13 1954-12-15 Ciba Ltd Manufacture of new dioxopiperidines
US2848455A (en) * 1955-07-18 1958-08-19 Ciba Pharm Prod Inc Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
US3057867A (en) * 1960-06-11 1962-10-09 Calandastiftung Inst Fur Wisse Glutarimide derivatives
DE1445652A1 (de) * 1961-09-07 1969-01-16 Distillers Co Yeast Ltd Neue Glutarimide und Verfahren zu deren Herstellung
US4668689A (en) * 1984-07-19 1987-05-26 National Research Development Corporation Glutarimide derivatives for treating oestrogen-dependent tumors

Also Published As

Publication number Publication date
PT85456B (pt) 1990-06-29
ATE73774T1 (de) 1992-04-15
IE872069L (en) 1988-01-31
DE3777500D1 (de) 1992-04-23
NO873193L (no) 1988-02-01
JPH0816100B2 (ja) 1996-02-21
US4839370A (en) 1989-06-13
DK397487A (da) 1988-02-01
FI85016C (fi) 1992-02-25
IL83367A0 (en) 1987-12-31
IL83367A (en) 1992-05-25
HU201740B (en) 1990-12-28
EP0258617A1 (de) 1988-03-09
HUT44498A (en) 1988-03-28
GR3004195T3 (fi) 1993-03-31
FI85016B (fi) 1991-11-15
DE3724520C2 (de) 1996-01-11
DE3724520A1 (de) 1988-03-03
JPS6341458A (ja) 1988-02-22
ES2039217T3 (es) 1993-09-16
IE60589B1 (en) 1994-07-27
NO170851C (no) 1992-12-16
DD264428A5 (de) 1989-02-01
ZA875653B (en) 1988-02-15
NO170851B (no) 1992-09-07
NO873193D0 (no) 1987-07-30
EP0258617B1 (de) 1992-03-18
PT85456A (de) 1987-08-01
FI873327A0 (fi) 1987-07-30
DK397487D0 (da) 1987-07-30

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MM Patent lapsed
MM Patent lapsed

Owner name: MADAUS AKTIENGESELLSCHAFT