FI872589A - Pyridinetanolaminderivat och deras framstaellning. - Google Patents

Pyridinetanolaminderivat och deras framstaellning. Download PDF

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Publication number
FI872589A
FI872589A FI872589A FI872589A FI872589A FI 872589 A FI872589 A FI 872589A FI 872589 A FI872589 A FI 872589A FI 872589 A FI872589 A FI 872589A FI 872589 A FI872589 A FI 872589A
Authority
FI
Finland
Prior art keywords
formula
pyridinethanolaminderivat
compounds
deras framstaellning
och deras
Prior art date
Application number
FI872589A
Other languages
English (en)
Finnish (fi)
Other versions
FI872589A0 (fi
Inventor
Leo Alig
Marcel Mueller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI872589A0 publication Critical patent/FI872589A0/fi
Publication of FI872589A publication Critical patent/FI872589A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Dental Preparations (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI872589A 1986-06-27 1987-06-10 Pyridinetanolaminderivat och deras framstaellning. FI872589A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH260886 1986-06-27
CH118687 1987-03-27

Publications (2)

Publication Number Publication Date
FI872589A0 FI872589A0 (fi) 1987-06-10
FI872589A true FI872589A (fi) 1987-12-28

Family

ID=25686931

Family Applications (1)

Application Number Title Priority Date Filing Date
FI872589A FI872589A (fi) 1986-06-27 1987-06-10 Pyridinetanolaminderivat och deras framstaellning.

Country Status (18)

Country Link
US (2) US4800206A (fr)
EP (1) EP0254856B1 (fr)
AT (1) ATE66916T1 (fr)
AU (1) AU594788B2 (fr)
CA (1) CA1287061C (fr)
DE (1) DE3772660D1 (fr)
DK (1) DK166207C (fr)
ES (1) ES2038619T3 (fr)
FI (1) FI872589A (fr)
GR (1) GR3003227T3 (fr)
HU (1) HU198457B (fr)
IL (1) IL82945A (fr)
MC (1) MC1831A1 (fr)
NO (1) NO170973C (fr)
NZ (1) NZ220793A (fr)
PH (1) PH25295A (fr)
PT (1) PT85184B (fr)
ZW (1) ZW10587A1 (fr)

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DE3627663A1 (de) * 1986-08-14 1988-03-03 Bayer Ag Heteroarylethylamine, verfahren zu ihrer herstellung und ihre verwendung als leistungsfoerderer bei tieren
DE3729284A1 (de) * 1987-09-02 1989-03-23 Thomae Gmbh Dr K Neue heteroarylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
FI892341A (fi) * 1988-06-10 1989-12-11 Hoffmann La Roche Propanolaminderivat.
DE3918834A1 (de) * 1989-01-26 1990-08-02 Bayer Ag Aryl- und heteroarylethanol-pyridylalkylamine, verfahren zu ihrer herstellung und ihre verwendung als leistungsfoerderer bei tieren und als mittel gegen adipositas
DE3905028A1 (de) * 1989-02-18 1990-08-23 Bayer Ag 2,4-dihalogen-6-pyridylethanolphenylisopropylamine, verfahren zu ihrer herstellung und ihre verwendung zur verschiebung des protein-fett-verhaeltnisses zugunsten von protein
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
WO1996035671A1 (fr) * 1995-05-10 1996-11-14 Pfizer Inc. AGONISTES DU RECEPTEUR β-ADRENERGIQUE
GB2305665A (en) * 1995-09-26 1997-04-16 Merck & Co Inc Selective ß3 agonists for the treatment of diabetes aand obesity
US6677347B2 (en) * 2000-12-08 2004-01-13 3M Innovative Properties Company Sulfonamido ether substituted imidazoquinolines
MXPA05000663A (es) * 2002-07-17 2005-09-20 Lek Pharmaceuticals Derivados novedosos de piridiletanol (feniletil) aminas como inhibidores de la biosintesis de colesterol, proceso para su preparacion, y composiciones farmaceuticas que los contienen.
US20040214851A1 (en) * 2003-04-28 2004-10-28 3M Innovative Properties Company Compositions and methods for induction of opioid receptors
AR045260A1 (es) * 2003-08-12 2005-10-19 3M Innovative Properties Co Compuestos que contienen imidazo-oxima sustituidos
NZ545412A (en) * 2003-08-27 2008-12-24 Coley Pharm Group Inc Aryloxy and arylalkyleneoxy substituted imidazoquinolines
CA2537763A1 (fr) * 2003-09-05 2005-03-17 3M Innovative Properties Company Traitement pour le lymphome a cellules b cd5<sp>+</sp>
US20090075980A1 (en) * 2003-10-03 2009-03-19 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and Analogs Thereof
JP5043435B2 (ja) * 2003-10-03 2012-10-10 スリーエム イノベイティブ プロパティズ カンパニー アルコキシ置換イミダゾキノリン
US7544697B2 (en) * 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
CA2545825A1 (fr) * 2003-11-14 2005-06-02 3M Innovative Properties Company Composes d'un anneau d'imidazo substitue par hydroxylamine
WO2005048933A2 (fr) 2003-11-14 2005-06-02 3M Innovative Properties Company Composes d'un anneau d'imidazo substitues par oxime
WO2005051317A2 (fr) * 2003-11-25 2005-06-09 3M Innovative Properties Company Systèmes cycliques d'imidazo substitués et procédés
US8802853B2 (en) * 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
JP2007517044A (ja) * 2003-12-30 2007-06-28 スリーエム イノベイティブ プロパティズ カンパニー イミダゾキノリニル、イミダゾピリジニル、およびイミダゾナフチリジニルスルホンアミド
US8697873B2 (en) * 2004-03-24 2014-04-15 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (fr) * 2004-06-15 2005-12-29 3M Innovative Properties Company Imidazoquinolines et imidazonaphthyridines substituees par un heterocyclyle contenant un azote
WO2006065280A2 (fr) * 2004-06-18 2006-06-22 3M Innovative Properties Company Composes a noyau imidazo a substitutif d'isoxazole, de dihydroisoxazole et d'oxadiazole
US7897609B2 (en) * 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
WO2006009832A1 (fr) * 2004-06-18 2006-01-26 3M Innovative Properties Company Systemes cycliques imidazo substitues, et procedes correspondants
US8026366B2 (en) * 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US20090270443A1 (en) * 2004-09-02 2009-10-29 Doris Stoermer 1-amino imidazo-containing compounds and methods
WO2006063072A2 (fr) * 2004-12-08 2006-06-15 3M Innovative Properties Company Compositions, combinaisons immunomodulatrices et procedes associes
ES2392647T3 (es) * 2004-12-30 2012-12-12 3M Innovative Properties Company Compuestos tetracíclicos quirales que inducen la biosíntesis de interferón
JP5313502B2 (ja) 2004-12-30 2013-10-09 スリーエム イノベイティブ プロパティズ カンパニー 置換キラル縮合[1,2]イミダゾ[4,5−c]環状化合物
AU2006210392A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune response modifiers
AU2006213746A1 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo(4,5-c) ring compounds and methods
US7943610B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company Pyrazolopyridine-1,4-diamines and analogs thereof
CA2602590A1 (fr) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. Composes cycliques 1-pyrazolo[3,4-c] substitues comme modulateurs de la biosynthese de cytokine destines au traitement d'infections virales et de maladies neoplastiques
WO2008008432A2 (fr) * 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Composés à cycle [1,2] imidazo [4,5-c] fusionné chiral substitué et procédés correspondants
AU2019288677A1 (en) 2018-06-21 2021-01-14 Yumanity Therapeutics, Inc. Compositions and methods for the treatment and prevention of neurological disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI791727A (fi) * 1978-06-05 1979-12-06 Ciba Geigy Ag Foerfarande foer framstaellning av n-alkylerade aminoalkoholer
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
EP0023385B1 (fr) * 1979-06-16 1982-12-15 Beecham Group Plc Dérivés d'éthanamines, leur préparation et leur utilisation dans des compositions pharmaceutiques
US4358455A (en) * 1980-12-23 1982-11-09 Merck & Co., Inc. Aralkylamindethanol heterocyclic compounds
DE3271132D1 (en) * 1981-07-11 1986-06-19 Beecham Group Plc Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application
EP0099707B1 (fr) * 1982-07-16 1986-12-10 Beecham Group Plc Dérivés d'éther 2-aminoéthyles, leurs procédés de préparation et compositions pharmaceutiques les contenant
CA1258454A (fr) * 1982-08-10 1989-08-15 Leo Alig Phenethanolamines
DE3462789D1 (en) * 1983-08-17 1987-04-30 Beecham Group Plc 2-phenylethylamine derivatives
GB8415377D0 (en) * 1984-06-15 1984-07-18 Beecham Group Plc Compounds
GB8528633D0 (en) * 1985-11-21 1985-12-24 Beecham Group Plc Compounds

Also Published As

Publication number Publication date
DK166207B (da) 1993-03-22
DE3772660D1 (de) 1991-10-10
EP0254856A3 (en) 1989-02-08
EP0254856A2 (fr) 1988-02-03
HU198457B (en) 1989-10-30
DK329587A (da) 1987-12-28
AU7455787A (en) 1988-01-07
AU594788B2 (en) 1990-03-15
NZ220793A (en) 1990-01-29
IL82945A (en) 1991-06-10
DK166207C (da) 1993-08-16
US4988714A (en) 1991-01-29
FI872589A0 (fi) 1987-06-10
CA1287061C (fr) 1991-07-30
DK329587D0 (da) 1987-06-26
ATE66916T1 (de) 1991-09-15
IL82945A0 (en) 1987-12-20
US4800206A (en) 1989-01-24
GR3003227T3 (en) 1993-02-17
HUT44508A (en) 1988-03-28
NO872701L (no) 1987-12-28
ZW10587A1 (en) 1988-01-13
NO170973C (no) 1993-01-06
EP0254856B1 (fr) 1991-09-04
PH25295A (en) 1991-04-30
PT85184A (en) 1987-07-01
NO170973B (no) 1992-09-28
ES2038619T3 (es) 1993-08-01
NO872701D0 (no) 1987-06-26
MC1831A1 (fr) 1988-06-03
PT85184B (pt) 1990-03-30

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FD Application lapsed

Owner name: F. HOFFMANN-LA ROCHE AG