FI853255L - Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin. - Google Patents

Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin.

Info

Publication number
FI853255L
FI853255L FI853255A FI853255A FI853255L FI 853255 L FI853255 L FI 853255L FI 853255 A FI853255 A FI 853255A FI 853255 A FI853255 A FI 853255A FI 853255 L FI853255 L FI 853255L
Authority
FI
Finland
Prior art keywords
bensazepine
framstaellning
tetrahydro
chloro
methyl
Prior art date
Application number
FI853255A
Other languages
English (en)
Finnish (fi)
Other versions
FI853255A7 (fi
FI853255A0 (fi
Inventor
Stanley John Borowski
Thomas Anthony Post
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of FI853255A0 publication Critical patent/FI853255A0/fi
Publication of FI853255A7 publication Critical patent/FI853255A7/fi
Publication of FI853255L publication Critical patent/FI853255L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI853255A 1984-09-05 1985-08-23 Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin. FI853255L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/647,552 US4541954A (en) 1984-09-05 1984-09-05 Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Publications (3)

Publication Number Publication Date
FI853255A0 FI853255A0 (fi) 1985-08-23
FI853255A7 FI853255A7 (fi) 1986-03-06
FI853255L true FI853255L (fi) 1986-03-06

Family

ID=24597406

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853255A FI853255L (fi) 1984-09-05 1985-08-23 Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin.

Country Status (19)

Country Link
US (1) US4541954A (OSRAM)
EP (1) EP0174118A3 (OSRAM)
JP (1) JPS6168469A (OSRAM)
KR (1) KR860002470A (OSRAM)
AU (1) AU581918B2 (OSRAM)
CA (1) CA1244017A (OSRAM)
DK (1) DK379985A (OSRAM)
EG (1) EG17149A (OSRAM)
ES (1) ES8609266A1 (OSRAM)
FI (1) FI853255L (OSRAM)
GR (1) GR852041B (OSRAM)
HU (1) HU194181B (OSRAM)
IL (1) IL76100A0 (OSRAM)
NO (1) NO853255L (OSRAM)
NZ (1) NZ213141A (OSRAM)
PH (1) PH20796A (OSRAM)
PT (1) PT81018B (OSRAM)
ZA (1) ZA856268B (OSRAM)
ZW (1) ZW13385A1 (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000811A1 (en) * 1991-07-01 1993-01-21 The General Hospital Corporation Invertebrate phenylethanolamine transporter and the use thereof
EP0570590B1 (en) * 1991-12-06 1997-03-26 Yuasa Corporation Thin battery and monolithic thin battery
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
CA2888392A1 (en) 2003-06-17 2005-03-03 Arena Pharmaceuticals, Inc. Processes for preparing 3-benzazepines
MXPA05013364A (es) 2003-06-17 2006-03-17 Arena Pharm Inc Procedimiento para preparar 3-benzazepinas.
US8168624B2 (en) 2004-12-21 2012-05-01 Arena Pharmaceuticals, Inc. Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
AU2005322183B2 (en) 2004-12-23 2012-03-29 Arena Pharmaceuticals, Inc. 5HT2C receptor modulator compositions and methods of use
JP5199997B2 (ja) * 2006-04-03 2013-05-15 アリーナ ファーマシューティカルズ, インコーポレイテッド 8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンズアゼピンおよびこれに関連する中間体を調製するためのプロセス
CA2670285A1 (en) * 2006-12-05 2008-06-12 Arena Pharmaceuticals, Inc. Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
JP5491421B2 (ja) * 2008-03-04 2014-05-14 アリーナ ファーマシューティカルズ, インコーポレイテッド 5−ht2cアゴニストである(r)−8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンゾアゼピンに関連する中間体の調製のためのプロセス
EP2443080A2 (en) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Process for the preparation of 5-ht2c receptor agonists
US9045431B2 (en) 2010-06-02 2015-06-02 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
WO2012030938A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
SG188362A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Modified-release dosage forms of 5-ht2c agonists useful for weight management
EP2611449A1 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Administration of lorcaserin to individuals with renal impairment
AU2011296033A1 (en) 2010-09-01 2013-04-04 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-HT2C agonists
AR088670A1 (es) 2012-10-09 2014-06-25 Arena Pharm Inc Metodo de control del peso

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1118688A (en) * 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US4251660A (en) * 1978-08-10 1981-02-17 Smithkline Corporation Method for preparing tetrahydroisoquinolines
US4200754A (en) * 1979-02-02 1980-04-29 Smithkline Corporation Method for preparing 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline
ZA827887B (en) * 1981-11-27 1983-11-30 Smithkline Beckman Corp Pharmaceutical compositions and method of producing alpha2 antagonism
IE53962B1 (en) * 1981-11-27 1989-04-26 Smithkline Beckman Corp 3-benzazepines as alpha-2 antagonists
EP0080779B1 (en) * 1981-11-27 1986-07-16 Smithkline Beckman Corporation 3-benzazepines as alpha-2 antagonists

Also Published As

Publication number Publication date
CA1244017A (en) 1988-11-01
ES8609266A1 (es) 1986-09-01
FI853255A7 (fi) 1986-03-06
FI853255A0 (fi) 1985-08-23
NZ213141A (en) 1988-07-28
PT81018A (en) 1985-09-01
GR852041B (OSRAM) 1985-12-19
EG17149A (en) 1989-06-30
ZA856268B (en) 1986-07-30
JPS6168469A (ja) 1986-04-08
NO853255L (no) 1986-03-06
AU4648185A (en) 1986-03-13
HUT38617A (en) 1986-06-30
ZW13385A1 (en) 1985-11-20
EP0174118A3 (en) 1986-12-30
HU194181B (en) 1988-01-28
KR860002470A (ko) 1986-04-26
EP0174118A2 (en) 1986-03-12
DK379985D0 (da) 1985-08-21
ES546285A0 (es) 1986-09-01
AU581918B2 (en) 1989-03-09
PH20796A (en) 1987-04-14
IL76100A0 (en) 1985-12-31
US4541954A (en) 1985-09-17
PT81018B (en) 1987-06-24
DK379985A (da) 1986-03-06

Similar Documents

Publication Publication Date Title
FI853193A0 (fi) Smaertstillande 1,2-benzisotiazol-3 -ylpiperazinderivat.
FI854625L (fi) Foerfarande foer framstaellning av pulverformigt, lineaert, basiskt polymerat.
FI853255L (fi) Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin.
MX21592A (es) 1,3-oxazolidin-2-ona.
FI852765L (fi) Foerfarande foer framstaellning av saosom hjaertmedicin anvaendbara 1,6-naftyridin 2(1h)-oner.
FI852616L (fi) Foerfarande foer uppvaermning av tjockvaeggiga glasroer, jaemte anordning.
FI853837L (fi) Foerfarande foer framstaellning av isolerande, poroesa, formade byggelement.
FI853686L (fi) Foerfarande foer framstaellning av 2,4 -diklor-5-fluorbensoesyra.
FI852899L (fi) Foerfarande foer framstaellning av fenylsubstituerade 2,4,6,8-nonatetraensyror.
DE3585315D1 (de) 5,6,7,8-tetrafluoranthrachinonderivate.
FI841003L (fi) Foerfarande foer framstaellning av staellningar, speciellt stegar.
DE3586745D1 (de) 9,11-epoxy-21-hydroxypregnan-derivate.
FI853421A0 (fi) 7-oxo-4-tia-1-azabicyklo/3,2,0/ hept-2-enderivat.
FI853585A0 (fi) Foerfarande foer framstaellning av aromatiska 1,4-oxazepinoner och -tioner.
FI851520A0 (fi) Anordning foer sammanpressning av en blaosfolieslang.
FI855017L (fi) Foerfarande foer framstaellning av 26,26,26-trifluor-1 ,25-dihydroxikolekalciferol.
FI850604A0 (fi) Anordning foer styckevis tvaermaetning av laongstraeckta foeremaol, foeretraedesvis virkesstycken.
FI843270A0 (fi) Foerfarande foer industriellt utnyttjande av till en tjocklek av 0,2-0,3 mm skuret traefaner.
FI852372L (fi) Foerfarande foer framstaellning av substituerade 1,3-dioxanderivat.
FI902192A0 (fi) Foerfarande foer framstaellning av 1,3-dihydro-4-pyridinyl-2h-imidazol-2-oner.
FI850758A0 (fi) Foerfarande foer framstaellning av 3-metyl-7-fluor-5-nitrobenzotiofen.
FI850668A0 (fi) Anordning foer behandling av roekgaser, speciellt avgaser.
FI841632A0 (fi) Foerfarande foer framstaellning av laett instaellbara, haollbara anod- och jaernfoerelseelektrodkomponenter foer katod katodiskt skydd.
FI843391A7 (fi) Foerfarande foer framstaellning av osymmetriska 1,4-dihydropyridin dikarboxylsyraestrar.
FI842639A0 (fi) Acylderivat av 1,4,3,6-dianhydro- hexitol.

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: SMITHKLINE BECKMAN CORPORATION