FI843013A - N6-substituerade adenosiner. - Google Patents

N6-substituerade adenosiner. Download PDF

Info

Publication number
FI843013A
FI843013A FI843013A FI843013A FI843013A FI 843013 A FI843013 A FI 843013A FI 843013 A FI843013 A FI 843013A FI 843013 A FI843013 A FI 843013A FI 843013 A FI843013 A FI 843013A
Authority
FI
Finland
Prior art keywords
adenosiner
substitute
substitute adenosiner
Prior art date
Application number
FI843013A
Other languages
English (en)
Other versions
FI843013A0 (fi
FI77666B (fi
FI77666C (fi
Inventor
James A Bristol
Walter H Moos
Bharat Trivedi
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of FI843013A0 publication Critical patent/FI843013A0/fi
Publication of FI843013A publication Critical patent/FI843013A/fi
Publication of FI77666B publication Critical patent/FI77666B/fi
Application granted granted Critical
Publication of FI77666C publication Critical patent/FI77666C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/22—Pteridine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI843013A 1983-08-01 1984-07-30 Foerfarande foer framstaellning av farmaceutiskt anvaendbara n6-substituerade adenosiner. FI77666C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51928483A 1983-08-01 1983-08-01
US51928483 1983-08-01
US62194384A 1984-06-22 1984-06-22
US62194384 1984-06-22

Publications (4)

Publication Number Publication Date
FI843013A0 FI843013A0 (fi) 1984-07-30
FI843013A true FI843013A (fi) 1985-02-02
FI77666B FI77666B (fi) 1988-12-30
FI77666C FI77666C (fi) 1989-04-10

Family

ID=27059783

Family Applications (1)

Application Number Title Priority Date Filing Date
FI843013A FI77666C (fi) 1983-08-01 1984-07-30 Foerfarande foer framstaellning av farmaceutiskt anvaendbara n6-substituerade adenosiner.

Country Status (14)

Country Link
EP (2) EP0139358B1 (fi)
AU (1) AU570058B2 (fi)
CA (1) CA1239397A (fi)
DE (1) DE3475074D1 (fi)
DK (1) DK159855C (fi)
ES (1) ES8604258A1 (fi)
FI (1) FI77666C (fi)
GR (1) GR82224B (fi)
HU (1) HUT34990A (fi)
IL (1) IL72422A (fi)
NO (1) NO158876C (fi)
NZ (1) NZ209064A (fi)
PH (2) PH21507A (fi)
PT (1) PT79008B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE50777T1 (de) * 1984-04-18 1990-03-15 Whitby Research Inc Cardio-vasodilatatore n-6-substituierte adenosine.
US4657897A (en) * 1984-06-22 1987-04-14 Warner-Lambert Company N6 -substituted adenosines for treating pain
US4582823A (en) * 1984-08-15 1986-04-15 Warner-Lambert Company Method for treating schizophrenia and medicaments therefor
AU577743B2 (en) * 1984-10-26 1988-09-29 Warner-Lambert Company N6-benzopyrano and benzothiopyrano adenosines
US4738954A (en) * 1985-11-06 1988-04-19 Warner-Lambert Company Novel N6 -substituted-5'-oxidized adenosine analogs
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
AU8276187A (en) * 1986-10-31 1988-05-25 Warner-Lambert Company Selected n6-substituted adenosines having selective a2 binding activity
WO1988003148A2 (en) * 1986-10-31 1988-05-05 Warner-Lambert Company Heteroaromatic derivatives of adenoside
US4908441A (en) * 1988-07-19 1990-03-13 Warner-Lambert Company Deoxyadenosine compounds and methods of making and using the same
GB2226027B (en) * 1988-12-13 1992-05-20 Sandoz Ltd Adenosine derivatives,their production and use
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
FR2687678B1 (fr) * 1992-01-31 1995-03-31 Union Pharma Scient Appl Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
EP1090022B1 (en) 1998-06-23 2003-08-06 Glaxo Group Limited 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
PE20060272A1 (es) 2004-05-24 2006-05-22 Glaxo Group Ltd (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB116580A (en) * 1917-07-07 1918-06-20 Thomas Camk Improvements in Air-lifs for Sewage Sludge.
NL128629C (fi) * 1966-05-07
DE1795828A1 (de) * 1966-12-21 1975-11-27 Boehringer Mannheim Gmbh Adenosinderivate
DE1670265A1 (de) * 1967-08-25 1971-01-28 Boehringer Mannheim Gmbh 2-Amino-Adenosinderivate und Verfahren zu deren Herstellung
DE2052596A1 (de) * 1970-10-27 1972-05-04 Boehringer Mannheim Gmbh, 6800 Mannheim Neuartige Verwendung von N(6)-substituierten Adenosin-Derivaten
DE2406587A1 (de) * 1974-02-12 1975-08-21 Klinge Co Chem Pharm Fab Hypolipaemisch wirksame adenosinderivate
US4501735A (en) * 1983-12-05 1985-02-26 Warner-Lambert Company N6-(1- and 2-benzocycloalkyl) adenosines

Also Published As

Publication number Publication date
EP0139358A2 (en) 1985-05-02
FI843013A0 (fi) 1984-07-30
PT79008A (en) 1984-09-01
AU570058B2 (en) 1988-03-03
EP0139358B1 (en) 1988-11-09
DK371584A (da) 1985-02-02
DK371584D0 (da) 1984-07-31
PH21507A (en) 1987-11-10
DE3475074D1 (en) 1988-12-15
EP0139358A3 (en) 1985-10-09
EP0251339A3 (en) 1989-07-26
PT79008B (en) 1986-09-08
NO158876B (no) 1988-08-01
PH21388A (en) 1987-10-15
NO843084L (no) 1985-02-04
EP0251339A2 (en) 1988-01-07
IL72422A0 (en) 1984-11-30
ES8604258A1 (es) 1986-01-16
HUT34990A (en) 1985-05-28
NZ209064A (en) 1989-02-24
FI77666B (fi) 1988-12-30
IL72422A (en) 1988-08-31
DK159855B (da) 1990-12-17
DK159855C (da) 1991-05-13
AU3078284A (en) 1985-02-07
GR82224B (fi) 1984-12-13
FI77666C (fi) 1989-04-10
ES534752A0 (es) 1986-01-16
NO158876C (no) 1988-11-09
CA1239397A (en) 1988-07-19

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: WARNER-LAMBERT COMPANY