FI833034A - Azetidinonderivater, ett foerfarande foer deras framstaellning samt deras anvaendning som intermedii framstaellning av karbapenem-antibioter - Google Patents

Azetidinonderivater, ett foerfarande foer deras framstaellning samt deras anvaendning som intermedii framstaellning av karbapenem-antibioter Download PDF

Info

Publication number
FI833034A
FI833034A FI833034A FI833034A FI833034A FI 833034 A FI833034 A FI 833034A FI 833034 A FI833034 A FI 833034A FI 833034 A FI833034 A FI 833034A FI 833034 A FI833034 A FI 833034A
Authority
FI
Finland
Prior art keywords
framstaellning
deras
karbapenem
azetidinonderivater
antibioter
Prior art date
Application number
FI833034A
Other languages
English (en)
Other versions
FI833034A0 (fi
FI80887B (fi
FI80887C (fi
Inventor
Sadao Oida
Akira Yoshida
Yawara Tajima
Noriko Takeda
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57145574A external-priority patent/JPS5946265A/ja
Priority claimed from JP57158604A external-priority patent/JPS5951286A/ja
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI833034A0 publication Critical patent/FI833034A0/fi
Publication of FI833034A publication Critical patent/FI833034A/fi
Publication of FI80887B publication Critical patent/FI80887B/fi
Application granted granted Critical
Publication of FI80887C publication Critical patent/FI80887C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/04—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI833034A 1982-08-24 1983-08-24 Azetidinonderivater, ett foerfarande foer deras framstaellning samt deras anvaendning som intermediater i framstaellning av karbapenem-antibioter. FI80887C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP14557482 1982-08-24
JP57145574A JPS5946265A (ja) 1982-08-24 1982-08-24 アゼチジノン誘導体の製造法
JP15860482 1982-09-10
JP57158604A JPS5951286A (ja) 1982-09-10 1982-09-10 カルバペネム誘導体の製造法

Publications (4)

Publication Number Publication Date
FI833034A0 FI833034A0 (fi) 1983-08-24
FI833034A true FI833034A (fi) 1984-02-25
FI80887B FI80887B (fi) 1990-04-30
FI80887C FI80887C (fi) 1990-08-10

Family

ID=26476650

Family Applications (1)

Application Number Title Priority Date Filing Date
FI833034A FI80887C (fi) 1982-08-24 1983-08-24 Azetidinonderivater, ett foerfarande foer deras framstaellning samt deras anvaendning som intermediater i framstaellning av karbapenem-antibioter.

Country Status (7)

Country Link
US (1) US5856556A (fi)
EP (1) EP0102239B1 (fi)
KR (1) KR900006449B1 (fi)
CA (1) CA1232903A (fi)
DE (1) DE3374063D1 (fi)
ES (3) ES525138A0 (fi)
FI (1) FI80887C (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696923A (en) * 1984-04-23 1987-09-29 Merck & Co., Inc. 6-[1-hydroxyethyl]-2-SR8 -1-methyl-1-carbadethiapen-2-em-3-carboxylic acids
DK270685A (da) * 1984-06-29 1985-12-30 Hoffmann La Roche Carbapenemderivater
US4895939A (en) * 1986-02-24 1990-01-23 Bristol-Myers Company High percentage β-yield synthesis of carbapenem intermediates
KR880006244A (ko) * 1986-11-24 1988-07-22 후지사와 도모 기찌 로 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법
EP0272455B1 (en) * 1986-11-24 1993-02-10 Fujisawa Pharmaceutical Co., Ltd. 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds
US4820815A (en) * 1987-09-01 1989-04-11 University Of Notre Dame Du Lac Azetidinone N-phosphonomethyl esters
US4925838A (en) * 1988-03-18 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
GB8811237D0 (en) * 1988-05-12 1988-06-15 Fujisawa Pharmaceutical Co 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives
US4963544A (en) * 1988-05-23 1990-10-16 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
GB8923844D0 (en) * 1989-10-23 1989-12-13 Fujisawa Pharmaceutical Co Carbapenem compounds
IL99513A0 (en) * 1990-09-20 1992-08-18 Hoechst Ag Process for the preparation of carbapenem compounds
GB9103034D0 (en) * 1991-02-13 1991-03-27 Fujisawa Pharmaceutical Co Processes for preparing carbapenem derivatives
GB9305813D0 (en) * 1993-03-20 1993-05-05 Glaxo Spa Chemical process
US6395894B2 (en) 1998-04-16 2002-05-28 Philip J. Pye Process for the synthesis of carbapenem intermidiates, and compounds produced
EP1104424B1 (en) 1998-06-17 2004-04-07 Merck & Co., Inc. Process for the synthesis of carbapenem intermediates
US6194568B1 (en) 1998-07-13 2001-02-27 Merck & Co., Inc. Process for synthesizing carbapenem intermediates
US7241308B2 (en) * 2003-06-09 2007-07-10 Xtent, Inc. Stent deployment systems and methods
GB0400382D0 (en) * 2004-01-09 2004-02-11 Glaxo Group Ltd Novel processes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348320A (en) * 1976-11-19 1982-09-07 Merck & Co., Inc. Substituted azetidiones
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
JPS579784A (en) * 1980-06-23 1982-01-19 Sankyo Co Ltd Production of penem-3-carboxylic derivative
DK329381A (da) * 1980-07-24 1982-01-25 Takeda Chemical Industries Ltd Fremgangsmaade til frmstilling af 1,1-disubstitueret carba-z -penem samt salte og estere deraf
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems
EP0057565A1 (en) * 1981-02-04 1982-08-11 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
ZA821361B (en) * 1981-03-04 1983-01-26 Beecham Group Plc Beta-lactam antibiotics,their preparation and use

Also Published As

Publication number Publication date
DE3374063D1 (en) 1987-11-19
ES8502708A1 (es) 1985-01-16
KR840006008A (ko) 1984-11-21
ES525138A0 (es) 1985-01-16
EP0102239B1 (en) 1987-10-14
ES531562A0 (es) 1985-09-01
EP0102239A1 (en) 1984-03-07
ES8602796A1 (es) 1985-12-01
US5856556A (en) 1999-01-05
FI833034A0 (fi) 1983-08-24
ES8507491A1 (es) 1985-09-01
FI80887B (fi) 1990-04-30
KR900006449B1 (ko) 1990-08-31
ES531561A0 (es) 1985-12-01
FI80887C (fi) 1990-08-10
CA1232903A (en) 1988-02-16

Similar Documents

Publication Publication Date Title
FI841480A (fi) Anvaendning av klordioxidgas som ett kemiskt steriliseringsmedel.
FI832827A (fi) Sjaelvbaerande limark, som utgoers av ett straengsprutbart smaeltlim
FI842555A0 (fi) Entsymsammansaettning foer rengoering, anvaendning av sammansaettningen samt framstaellning av densamma.
FI834522A (fi) 1-azolyl-2-aryl-3-fluoralkan-2-oler som mikrobicider.
FI863570A0 (fi) Foerfarande som katalyseras av ett transitionsmetallkomplex.
FI840667A (fi) Foerfarande foer framstaellning av en metallinsats samt metallinsats framstaelld enligt detta foerfarande.
FI830048L (fi) Anvaendning av stabiliserade, pelarformade leror i skikt som katalysatorer i reaktioner som katalyseras av protoner
FI833034A (fi) Azetidinonderivater, ett foerfarande foer deras framstaellning samt deras anvaendning som intermedii framstaellning av karbapenem-antibioter
FI832093L (fi) Antikoagulanter av 4-hydroxikumarintyp, deras framstaellning samt dessa innehaollande raottgiftskompositioner (beten)
FI832087A0 (fi) Av flere aemnen bestaoende anoder samt ackumulatorer, i vilka naemda anoder anvaends
FI821650A0 (fi) Framstaellning av kemiska foereningar samt deras anvaendning som laekemedel
FI820743L (fi) Banformningsparti foer pappersmaskin, som aer avsett modernisering av ett planviraparti
FI831428A0 (fi) Cykloalkanderivat, foerfarande foer framstaellning av dessa, samt blandningar innehaollande dessa
FI843139A (fi) Foerfarande foer framstaellning dihydrokarbylkarbonater, deras anvaendning som tillsatsmedel i braenslen samt dessa innehaollande braensleblandningar.
FI842054A (fi) Fuktbestaendiga taendstickor samt foerfarande foer deras framstaellning.
FI840130A (fi) Tvaerbundna urea-formaldehyd-poly- mermatris-kompositioner som innehaoller cykliska mellanstrukturer.
FI842899A (fi) Foerfarande foer markering samt anordning foer genomfoerande av foerfarandet.
FI840037A (fi) Smoerjningsaemnes- och tillaeggsaemnesblandningar foer alkoholbraensle samt foerfarande foer framstaellning av dessa.
FI822141A0 (fi) Med foerbindningsport foersedd, av plastfolie tillverkad foerpackning samt foerfarande foer tillverkning av foerbindningsporten
FI832625A (fi) Anordning i ett nyttolastfartyg, vilket utfoer saovael isbrytarfart som oeppenvattenfart
FI833421A0 (fi) Amidoglykosidderivat, foerfaranden foer deras framstaellning samt deras anvaendning
FI841975A0 (fi) Foerfarande foer belastningsmaetning av laongstraeckta, axelformiga foeremaol samt anordning foer foerfarandets foerver kligande.
FI824383L (fi) Arrangemang foer infaestning av foillister i pappers- eller cellulosamaskiner samt stoed- och faestbord.
FI830514L (fi) Bottenmaterial foer vaexelfoereskida, bottendel, foerfarande foer tillverkning av dessa samt skida
FI851506L (fi) Anvaendning av flygaska som tillsatsmedel i betongmassa.

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SANKYO COMPANY LIMITED