DK329381A - Fremgangsmaade til frmstilling af 1,1-disubstitueret carba-z -penem samt salte og estere deraf - Google Patents

Fremgangsmaade til frmstilling af 1,1-disubstitueret carba-z -penem samt salte og estere deraf

Info

Publication number
DK329381A
DK329381A DK329381A DK329381A DK329381A DK 329381 A DK329381 A DK 329381A DK 329381 A DK329381 A DK 329381A DK 329381 A DK329381 A DK 329381A DK 329381 A DK329381 A DK 329381A
Authority
DK
Denmark
Prior art keywords
penem
carba
disubstituted
esters
salts
Prior art date
Application number
DK329381A
Other languages
English (en)
Inventor
A Morimoto
T Miyawaki
K Yoshioka
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1980/000168 external-priority patent/WO1982000291A1/ja
Priority claimed from PCT/JP1981/000060 external-priority patent/WO1982003218A1/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK329381A publication Critical patent/DK329381A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/26—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK329381A 1980-07-24 1981-07-23 Fremgangsmaade til frmstilling af 1,1-disubstitueret carba-z -penem samt salte og estere deraf DK329381A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/JP1980/000168 WO1982000291A1 (en) 1980-07-24 1980-07-24 Carba-2-penem compounds and process for preparing same
PCT/JP1981/000060 WO1982003218A1 (fr) 1981-03-19 1981-03-19 Composes de carba-2-peneme et procede de preparation

Publications (1)

Publication Number Publication Date
DK329381A true DK329381A (da) 1982-01-25

Family

ID=26420991

Family Applications (1)

Application Number Title Priority Date Filing Date
DK329381A DK329381A (da) 1980-07-24 1981-07-23 Fremgangsmaade til frmstilling af 1,1-disubstitueret carba-z -penem samt salte og estere deraf

Country Status (2)

Country Link
EP (1) EP0045198A3 (da)
DK (1) DK329381A (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0060077A1 (en) * 1981-03-04 1982-09-15 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
KR900006449B1 (ko) * 1982-08-24 1990-08-31 상꾜 가부시끼가이샤 아제티디논 화합물의 제조방법
EP0160876A1 (en) * 1984-04-23 1985-11-13 Merck & Co. Inc. 1-Hetero-6-/1-Hydroxyethyl/-2-SR8-1-carbadethiapen-2-EM-3-carboxylic acids
DK270685A (da) * 1984-06-29 1985-12-30 Hoffmann La Roche Carbapenemderivater
US5138050A (en) * 1988-06-30 1992-08-11 Merck & Co., Inc. 6-amido-1-methyl carbapenems
US5395931A (en) * 1988-06-30 1995-03-07 Merck & Co., Inc. 6-amido-1-methyl-2-(substituted-thio)carbapenems
US5055463A (en) * 1989-02-02 1991-10-08 Merck & Co., Inc. Spirocyclic 6-amido carbapenems
US5672701A (en) * 1990-01-16 1997-09-30 Bristol-Myers Squibb Company 4-substituted alkyl carbapenem antibiotics
IL99513A0 (en) * 1990-09-20 1992-08-18 Hoechst Ag Process for the preparation of carbapenem compounds
EP0546742B1 (en) * 1991-12-09 2001-06-20 Takasago International Corporation 4-(1,1-Dialkoxycarbonyl-alkyl)azetidin-2-one derivatives and synthesis of 4-(1-carboxy-alkyl)azetidin-2-one derivatives therefrom
EP0638552B1 (en) * 1993-02-12 2003-06-04 Daiichi Suntory Pharma Co., Ltd. Process for synthesizing 4-substituted azetidinone derivative
EP0722945A1 (en) * 1995-01-18 1996-07-24 Zeneca Limited 9-oxo-1-azabicyclo(5.2.0)non-2,3-diene-2-carboxylic acid derivatives as antibiotics
US5719139A (en) * 1995-01-18 1998-02-17 Zeneca Limited 9-oxo-1-azabicyclo 5.2.0!non-2,4-diene-2-carboxylic acid compounds as antibiotics

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1906401A1 (de) * 1969-02-08 1970-08-27 Hoechst Ag Verfahren zur Herstellung von 4-Acyloxy-azetidin-2-onen
EP0030392B1 (en) * 1978-01-19 1984-05-16 Beecham Group Plc Intermediates for use in the preparation of carbapenems
IE51861B1 (en) * 1978-10-24 1987-04-15 Merck & Co Inc 6-,1-and 2-substituted-1-carbapen-2-em-3-carboxylic acids,processes for the preparation of such compounds and pharmaceutical compositions comprising such compounds
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids

Also Published As

Publication number Publication date
EP0045198A3 (en) 1982-08-04
EP0045198A2 (en) 1982-02-03

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment