FI832646A - Foereningar, som har angiotensin konverterande enzym inhiberande aktivitet och diuretisk aktivitet - Google Patents

Foereningar, som har angiotensin konverterande enzym inhiberande aktivitet och diuretisk aktivitet Download PDF

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Publication number
FI832646A
FI832646A FI832646A FI832646A FI832646A FI 832646 A FI832646 A FI 832646A FI 832646 A FI832646 A FI 832646A FI 832646 A FI832646 A FI 832646A FI 832646 A FI832646 A FI 832646A
Authority
FI
Finland
Prior art keywords
alkyl
cycloalkyl
aktivitet
heteroaryl
integer
Prior art date
Application number
FI832646A
Other languages
English (en)
Other versions
FI832646A0 (fi
Inventor
Edward S Neiss
John T Suh
John J Piwinski
Original Assignee
Usv Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp
Publication of FI832646A0 publication Critical patent/FI832646A0/fi
Publication of FI832646A publication Critical patent/FI832646A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/34Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI832646A 1982-07-21 1983-07-20 Foereningar, som har angiotensin konverterande enzym inhiberande aktivitet och diuretisk aktivitet FI832646A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40055582A 1982-07-21 1982-07-21

Publications (2)

Publication Number Publication Date
FI832646A0 FI832646A0 (fi) 1983-07-20
FI832646A true FI832646A (fi) 1984-01-22

Family

ID=23584069

Family Applications (1)

Application Number Title Priority Date Filing Date
FI832646A FI832646A (fi) 1982-07-21 1983-07-20 Foereningar, som har angiotensin konverterande enzym inhiberande aktivitet och diuretisk aktivitet

Country Status (13)

Country Link
EP (1) EP0100053B1 (fi)
JP (1) JPS5933251A (fi)
KR (1) KR840005711A (fi)
AT (1) ATE30320T1 (fi)
AU (1) AU561145B2 (fi)
DE (1) DE3374122D1 (fi)
DK (1) DK333983A (fi)
ES (1) ES8504107A1 (fi)
FI (1) FI832646A (fi)
IL (1) IL69228A0 (fi)
NO (1) NO832654L (fi)
NZ (1) NZ204961A (fi)
ZA (1) ZA835331B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54115075A (en) * 1978-02-28 1979-09-07 Cho Lsi Gijutsu Kenkyu Kumiai Plasma etching method
EP0127090A3 (en) * 1983-05-20 1985-08-28 Usv Pharmaceutical Corporation Angiotensin-converting enzyme inhibitors
US4576941A (en) * 1984-02-29 1986-03-18 Usv Pharmaceutical Corp. Compounds for treating hypertension
EP0284510A3 (en) * 1987-03-24 1990-08-22 Asahi Breweries, Ltd. N-[N alpha-(1(S)-carboxy-3-cyclohexyl-propyl)-1-lysyl] N-cyclopentylglycine as antihypertensives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4053651A (en) * 1976-05-10 1977-10-11 E. R. Squibb & Sons, Inc. Compounds and method for alleviating angiotensin related hypertension
US4256761A (en) * 1979-07-13 1981-03-17 Usv Pharmaceutical Corporation Antihypertensive amides
DE3044236A1 (de) * 1980-11-25 1982-06-16 Hoechst Ag, 6000 Frankfurt Aminosaeurederivate und verfahren zu ihrer herstellung
ZA811340B (en) * 1980-06-09 1982-03-31 Morton Norwich Products Inc N-(cycloalkyl)amino acid compounds

Also Published As

Publication number Publication date
NZ204961A (en) 1986-02-21
EP0100053A1 (en) 1984-02-08
NO832654L (no) 1984-01-23
JPS5933251A (ja) 1984-02-23
AU1698283A (en) 1984-01-26
DE3374122D1 (en) 1987-11-26
DK333983A (da) 1984-01-22
ES524324A0 (es) 1985-05-01
ES8504107A1 (es) 1985-05-01
FI832646A0 (fi) 1983-07-20
AU561145B2 (en) 1987-04-30
KR840005711A (ko) 1984-11-16
IL69228A0 (en) 1983-11-30
DK333983D0 (da) 1983-07-20
ATE30320T1 (de) 1987-11-15
EP0100053B1 (en) 1987-10-21
ZA835331B (en) 1984-04-25

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Legal Events

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FD Application lapsed

Owner name: USV PHARMACEUTICAL CORPORATION