FI823209A0 - Foerfarande foer framstaellning av nya aminometyl-1h-indol-4-metanolderivat och deras salter - Google Patents
Foerfarande foer framstaellning av nya aminometyl-1h-indol-4-metanolderivat och deras salterInfo
- Publication number
- FI823209A0 FI823209A0 FI823209A FI823209A FI823209A0 FI 823209 A0 FI823209 A0 FI 823209A0 FI 823209 A FI823209 A FI 823209A FI 823209 A FI823209 A FI 823209A FI 823209 A0 FI823209 A0 FI 823209A0
- Authority
- FI
- Finland
- Prior art keywords
- formula
- product
- see diagramm
- already indicated
- significance
- Prior art date
Links
- PEMZQGFPOMEHPI-UHFFFAOYSA-N [1-(aminomethyl)indol-4-yl]methanol Chemical class C1=CC=C2N(CN)C=CC2=C1CO PEMZQGFPOMEHPI-UHFFFAOYSA-N 0.000 title 1
- -1 aminomethyl 1H-indol-4-methanol Chemical compound 0.000 abstract 20
- 125000004432 carbon atom Chemical group C* 0.000 abstract 10
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 4
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 4
- 239000003638 chemical reducing agent Substances 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
- 229910052740 iodine Chemical group 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 239000011707 mineral Substances 0.000 abstract 2
- 150000007522 mineralic acids Chemical class 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 235000005985 organic acids Nutrition 0.000 abstract 2
- DITHIFQMPPCBCU-UHFFFAOYSA-N propa-1,2-diene Chemical compound [CH]=C=C DITHIFQMPPCBCU-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002475 indoles Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000011987 methylation Effects 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- LEIMLDGFXIOXMT-UHFFFAOYSA-N trimethylsilyl cyanide Chemical compound C[Si](C)(C)C#N LEIMLDGFXIOXMT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8117560A FR2512817A1 (fr) | 1981-09-17 | 1981-09-17 | Nouveaux derives de l'aminomethyl 1h-indole-4-methanol et leurs sels, leur procede de preparation, leur application a titre de medicaments, les compositions les renfermant et leurs intermediaires de preparation |
FR8117560 | 1981-09-17 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI823209A0 true FI823209A0 (fi) | 1982-09-16 |
FI823209L FI823209L (fi) | 1983-03-18 |
FI77444B FI77444B (fi) | 1988-11-30 |
FI77444C FI77444C (fi) | 1989-03-10 |
Family
ID=9262232
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI823209A FI77444C (fi) | 1981-09-17 | 1982-09-16 | Foerfarande foer framstaellning av nya aminometyl-1h-indol-4-metanolderivat och deras salter. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0076713B1 (fi) |
JP (1) | JPS5862161A (fi) |
AT (1) | ATE17347T1 (fi) |
AU (1) | AU550238B2 (fi) |
CA (1) | CA1200554A (fi) |
DE (1) | DE3268423D1 (fi) |
DK (1) | DK413482A (fi) |
ES (2) | ES515755A0 (fi) |
FI (1) | FI77444C (fi) |
FR (1) | FR2512817A1 (fi) |
HU (1) | HU189177B (fi) |
IE (1) | IE54262B1 (fi) |
PT (1) | PT75565B (fi) |
ZA (1) | ZA826497B (fi) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2591595B1 (fr) * | 1985-12-13 | 1988-09-09 | Roussel Uclaf | Nouveaux derives du 4-morpholinyl 1h-indole, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant, et intermediaires |
DE122010000031I1 (de) * | 1992-12-02 | 2010-10-21 | Kissei Pharmaceutical | Indolin Verbindungen zur Behandlung von Dysurien |
FR2792313A1 (fr) * | 1999-04-13 | 2000-10-20 | Synthelabo | Derives de 2-aminoethyl-indole, leur preparation et leur application en therapeutique |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1532210A (fr) * | 1963-06-21 | 1968-07-12 | Ici Ltd | Composés hétérocycliques et leur procédé de préparation |
FR2332010A1 (fr) * | 1975-11-18 | 1977-06-17 | Continental Pharma | Amino-alcool heterocyclique, son sel et son procede de preparation |
-
1981
- 1981-09-17 FR FR8117560A patent/FR2512817A1/fr active Granted
-
1982
- 1982-09-06 ZA ZA826497A patent/ZA826497B/xx unknown
- 1982-09-13 AT AT82401660T patent/ATE17347T1/de not_active IP Right Cessation
- 1982-09-13 EP EP82401660A patent/EP0076713B1/fr not_active Expired
- 1982-09-13 DE DE8282401660T patent/DE3268423D1/de not_active Expired
- 1982-09-15 PT PT75565A patent/PT75565B/pt not_active IP Right Cessation
- 1982-09-16 AU AU88452/82A patent/AU550238B2/en not_active Ceased
- 1982-09-16 DK DK413482A patent/DK413482A/da not_active Application Discontinuation
- 1982-09-16 HU HU822951A patent/HU189177B/hu not_active IP Right Cessation
- 1982-09-16 FI FI823209A patent/FI77444C/fi not_active IP Right Cessation
- 1982-09-16 ES ES515755A patent/ES515755A0/es active Granted
- 1982-09-16 IE IE2266/82A patent/IE54262B1/en not_active IP Right Cessation
- 1982-09-17 CA CA000411657A patent/CA1200554A/fr not_active Expired
- 1982-09-17 JP JP57161090A patent/JPS5862161A/ja active Pending
-
1983
- 1983-06-30 ES ES523718A patent/ES523718A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
PT75565B (fr) | 1985-12-09 |
PT75565A (fr) | 1982-10-01 |
CA1200554A (fr) | 1986-02-11 |
ES8401463A1 (es) | 1983-12-16 |
ES8403869A1 (es) | 1984-04-01 |
DK413482A (da) | 1983-03-18 |
ATE17347T1 (de) | 1986-01-15 |
DE3268423D1 (en) | 1986-02-20 |
FI77444C (fi) | 1989-03-10 |
FI77444B (fi) | 1988-11-30 |
ES523718A0 (es) | 1984-04-01 |
EP0076713A1 (fr) | 1983-04-13 |
IE54262B1 (en) | 1989-08-02 |
FR2512817B1 (fi) | 1983-12-30 |
IE822266L (en) | 1983-03-17 |
EP0076713B1 (fr) | 1986-01-08 |
JPS5862161A (ja) | 1983-04-13 |
FR2512817A1 (fr) | 1983-03-18 |
FI823209L (fi) | 1983-03-18 |
ZA826497B (en) | 1983-07-27 |
AU550238B2 (en) | 1986-03-13 |
AU8845282A (en) | 1983-03-24 |
HU189177B (en) | 1986-06-30 |
ES515755A0 (es) | 1983-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: ROUSSEL UCLAF SOCIETE ANONYME |