FI70793C - Foerfarande foer framstaellning av en stabil 4'-(9-akridinylamino)metansulfon -m-anisidin(m-amsa)-komposition - Google Patents

Foerfarande foer framstaellning av en stabil 4'-(9-akridinylamino)metansulfon -m-anisidin(m-amsa)-komposition Download PDF

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Publication number
FI70793C
FI70793C FI811474A FI811474A FI70793C FI 70793 C FI70793 C FI 70793C FI 811474 A FI811474 A FI 811474A FI 811474 A FI811474 A FI 811474A FI 70793 C FI70793 C FI 70793C
Authority
FI
Finland
Prior art keywords
amsa
lactic acid
water
solution
acridinylamino
Prior art date
Application number
FI811474A
Other languages
English (en)
Finnish (fi)
Other versions
FI811474L (fi
FI70793B (fi
Inventor
Murray Arthur Kaplan
Daniel Bouzard
Claude Perol
Jacques Stemer
Abraham Weber
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI811474L publication Critical patent/FI811474L/fi
Application granted granted Critical
Publication of FI70793B publication Critical patent/FI70793B/fi
Publication of FI70793C publication Critical patent/FI70793C/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI811474A 1980-05-16 1981-05-13 Foerfarande foer framstaellning av en stabil 4'-(9-akridinylamino)metansulfon -m-anisidin(m-amsa)-komposition FI70793C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14705680 1980-05-16
US06/147,056 US4360523A (en) 1980-05-16 1980-05-16 Pharmaceutical formulations of 4'-(9-acridinylamino)-methanesulfon-m-anisidide

Publications (3)

Publication Number Publication Date
FI811474L FI811474L (fi) 1981-11-17
FI70793B FI70793B (fi) 1986-07-18
FI70793C true FI70793C (fi) 1986-10-27

Family

ID=22520148

Family Applications (1)

Application Number Title Priority Date Filing Date
FI811474A FI70793C (fi) 1980-05-16 1981-05-13 Foerfarande foer framstaellning av en stabil 4'-(9-akridinylamino)metansulfon -m-anisidin(m-amsa)-komposition

Country Status (21)

Country Link
US (1) US4360523A (xx)
JP (1) JPS579716A (xx)
AT (1) AT374682B (xx)
AU (1) AU543726B2 (xx)
BE (1) BE888832A (xx)
CA (1) CA1160571A (xx)
CH (1) CH647677A5 (xx)
DE (1) DE3119510A1 (xx)
DK (1) DK159376C (xx)
FI (1) FI70793C (xx)
FR (1) FR2482458A1 (xx)
GB (1) GB2076288B (xx)
GR (1) GR75658B (xx)
IE (1) IE51285B1 (xx)
IT (1) IT1170970B (xx)
LU (1) LU83363A1 (xx)
NL (1) NL8102362A (xx)
NZ (1) NZ196985A (xx)
SE (1) SE460457B (xx)
YU (1) YU44831B (xx)
ZA (1) ZA813188B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4575509A (en) * 1983-01-31 1986-03-11 Bristol-Myers Company Water-soluble formulations of m-AMSA with pyroglutamic acid
US4626541A (en) * 1985-09-12 1986-12-02 Bristol-Myers Company Water soluble salt composition of m-AMSA
DE3844518A1 (de) * 1988-03-23 1989-10-05 Karl Heinz Dr Med Thiel Verwendung von aminochinolinen und aminopyridinen zur iontophoretischen behandlung maligner tumore
DE3819842C1 (xx) * 1988-03-23 1989-12-21 Karl Heinz Dr. 7100 Heilbronn De Thiel
CA2143515A1 (en) * 1994-03-22 1995-09-23 Prakash Parab Method for enhancing the rate of skin permeation of lactic acid through use of the l-enantiomer
WO2006002887A1 (en) * 2004-06-29 2006-01-12 Baxter International Inc. Aqueous drink solution of indibulin (d-24851) and an organic acid
DE102004031538A1 (de) * 2004-06-29 2006-02-09 Baxter International Inc., Deerfield Pharmazeutische Darreichungsform zur oralen Verabreichung eines schwerlöslichen Wirkstoffs, Verfahren zu deren Herstellung und Kit
EP1809279B1 (en) * 2004-11-08 2013-05-29 Baxter International Inc. Particulate compositions of tubulin inhibitor
EP2091532A1 (en) * 2006-11-28 2009-08-26 Ziopharm Oncology, Inc. Use of indolyl-3-glyoxylic acid derivatives including indibulin, alone or in combination with further agents for treating cancer
WO2015150383A1 (en) * 2014-03-31 2015-10-08 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Glycolic acid and/or d-lactic acid for the treatment of neurodegenerative diseases

Also Published As

Publication number Publication date
DK159376C (da) 1991-03-25
SE460457B (sv) 1989-10-16
IT8148467A0 (it) 1981-05-14
DE3119510A1 (de) 1982-02-25
AT374682B (de) 1984-05-25
JPS579716A (en) 1982-01-19
FR2482458B1 (xx) 1984-12-14
ZA813188B (en) 1982-05-26
NZ196985A (en) 1983-06-17
CA1160571A (en) 1984-01-17
BE888832A (fr) 1981-11-16
ATA221181A (de) 1983-10-15
JPH0136445B2 (xx) 1989-07-31
YU112381A (en) 1985-03-20
NL8102362A (nl) 1981-12-16
GR75658B (xx) 1984-08-02
DK216681A (da) 1981-11-17
SE8103071L (sv) 1981-11-17
US4360523A (en) 1982-11-23
CH647677A5 (de) 1985-02-15
GB2076288B (en) 1983-12-14
FR2482458A1 (fr) 1981-11-20
IT1170970B (it) 1987-06-03
IE51285B1 (en) 1986-11-26
FI811474L (fi) 1981-11-17
FI70793B (fi) 1986-07-18
DE3119510C2 (xx) 1991-03-07
LU83363A1 (fr) 1982-01-20
AU543726B2 (en) 1985-05-02
YU44831B (en) 1991-04-30
DK159376B (da) 1990-10-08
IE811092L (en) 1981-11-16
AU7029181A (en) 1981-11-19
GB2076288A (en) 1981-12-02

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BRISTOL-MYERS CO