FI67535C - Foerfarande foer framstaellning av nya biologiskt aktiva tricykliska aminer - Google Patents

Foerfarande foer framstaellning av nya biologiskt aktiva tricykliska aminer Download PDF

Info

Publication number
FI67535C
FI67535C FI813437A FI813437A FI67535C FI 67535 C FI67535 C FI 67535C FI 813437 A FI813437 A FI 813437A FI 813437 A FI813437 A FI 813437A FI 67535 C FI67535 C FI 67535C
Authority
FI
Finland
Prior art keywords
formula
hexahydro
group
hcl
alkyl
Prior art date
Application number
FI813437A
Other languages
English (en)
Finnish (fi)
Other versions
FI813437L (fi
FI67535B (fi
Inventor
Johannes Hubertus Wieringa
Der Vlugt Frans Abraham Van
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI813437L publication Critical patent/FI813437L/fi
Application granted granted Critical
Publication of FI67535B publication Critical patent/FI67535B/fi
Publication of FI67535C publication Critical patent/FI67535C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI813437A 1980-05-30 1981-11-02 Foerfarande foer framstaellning av nya biologiskt aktiva tricykliska aminer FI67535C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL8003141A NL8003141A (nl) 1980-05-30 1980-05-30 Biologisch aktieve tricyclische aminen.
NL8003141 1980-05-30
PCT/EP1981/000055 WO1981003490A1 (en) 1980-05-30 1981-05-21 Biologically-active tricyclic amines,methods for their preparation and pharmaceutical compositions containing same
EP8100055 1981-05-21

Publications (3)

Publication Number Publication Date
FI813437L FI813437L (fi) 1981-11-02
FI67535B FI67535B (fi) 1984-12-31
FI67535C true FI67535C (fi) 1985-04-10

Family

ID=19835385

Family Applications (1)

Application Number Title Priority Date Filing Date
FI813437A FI67535C (fi) 1980-05-30 1981-11-02 Foerfarande foer framstaellning av nya biologiskt aktiva tricykliska aminer

Country Status (17)

Country Link
US (1) US4564698A (de)
EP (1) EP0041293B1 (de)
JP (1) JPS57500734A (de)
AT (1) ATE6635T1 (de)
AU (1) AU546950B2 (de)
CA (1) CA1157472A (de)
DE (1) DE3162608D1 (de)
DK (1) DK152284C (de)
ES (1) ES8207500A1 (de)
FI (1) FI67535C (de)
GR (1) GR74556B (de)
HU (1) HU183490B (de)
IE (1) IE51611B1 (de)
NL (1) NL8003141A (de)
PT (1) PT73081B (de)
WO (1) WO1981003490A1 (de)
ZA (1) ZA813498B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU588962B2 (en) * 1985-12-31 1989-09-28 Upjohn Company, The 2,3-dihydro-1h-phenalene-2-amino compounds
WO1989010741A1 (en) * 1988-05-09 1989-11-16 The Upjohn Company Anxiolytic/anti-depressant 2,3-dihydro-1h-phenalen-2-amines
US5055414A (en) * 1988-07-05 1991-10-08 Eastman Kodak Company Phenalenimine fluorescent dyes and their use in analytical methods
IE892812L (en) * 1988-09-12 1990-03-12 Brendan Coleman Tricyclic aromatase inhibitors
FR2732964B1 (fr) * 1995-04-14 1997-05-16 Adir Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2589934A (en) * 1950-08-24 1952-03-18 Abbott Lab 2-aminomethyl-tetrahydroacenapthones-1 and their preparation
US3198835A (en) * 1960-07-25 1965-08-03 Sterling Drug Inc Pyrenyl methyl tertiary amino amines
US3553093A (en) * 1965-03-19 1971-01-05 Xerox Corp Color photoelectrophoretic imaging process
US3637740A (en) * 1969-04-21 1972-01-25 Pfizer Aminobenzocycloalkane compounds
US3912781A (en) * 1969-06-24 1975-10-14 Ruetgerswerke Ag 1-hydroxymethyl-1,2,3,4-tetrahydrofluoranthene
US3732299A (en) * 1969-11-03 1973-05-08 Squibb & Sons Inc Acenaphthene carboxamides
US3763233A (en) * 1971-08-17 1973-10-02 Sandoz Ag 7-substituted-hexahydro pleiadenes
DE2252945A1 (de) * 1971-11-19 1974-05-09 Basf Ag L-aminomethyl-acenaphthene und verfahren zu ihrer herstellung
NL7306069A (de) * 1973-05-02 1974-11-05
JPS52133993A (en) * 1976-04-29 1977-11-09 Takeda Chem Ind Ltd 1.2-dihydronaphthalene derivatives and method of preparing the same
GB1590648A (en) * 1976-12-01 1981-06-03 Ciba Geigy Ag N-((naphthothienyl or n-phenanthryl)alkyl) imidazoles their preparation and compositions containing them
DE2862103D1 (en) * 1977-08-19 1982-11-18 Sandoz Ag Propenyl amines, processes for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
PT73081B (en) 1984-10-22
EP0041293A1 (de) 1981-12-09
DE3162608D1 (en) 1984-04-19
ES502629A0 (es) 1982-10-01
NL8003141A (nl) 1982-01-04
IE51611B1 (en) 1987-01-21
AU7173081A (en) 1981-12-21
DK452681A (da) 1981-12-10
GR74556B (de) 1984-06-29
PT73081A (en) 1981-06-01
ES8207500A1 (es) 1982-10-01
DK152284B (da) 1988-02-15
ATE6635T1 (de) 1984-03-15
WO1981003490A1 (en) 1981-12-10
ZA813498B (en) 1982-06-30
CA1157472A (en) 1983-11-22
US4564698A (en) 1986-01-14
IE811144L (en) 1981-11-30
FI813437L (fi) 1981-11-02
HU183490B (en) 1984-05-28
JPS57500734A (de) 1982-04-30
EP0041293B1 (de) 1984-03-14
FI67535B (fi) 1984-12-31
DK152284C (da) 1988-08-08
AU546950B2 (en) 1985-09-26

Similar Documents

Publication Publication Date Title
JP2883297B2 (ja) 合成興奮性アミノ酸
US6127414A (en) NPY antagonists
JP2007537182A (ja) 鎮痛活性を有する3,6−ジアザビシクロ[3.1.1]ヘプタン誘導体
FI67535C (fi) Foerfarande foer framstaellning av nya biologiskt aktiva tricykliska aminer
JP2543690B2 (ja) 医薬組成物
FR2659323A1 (fr) Derives de 4-(aminomethyl) piperidine, leur preparation et leur application en therapeutique.
CS219944B2 (en) Method of making the racemic and optically unite derivatives of the 1-phenyl-2-cyclohexen-1-alkylamine
AU639742B2 (en) New bicyclic amino-substituted compounds
GB1598667A (en) 1,3-dioxolane derivatives and their use in the preparation of 1-amino-3-aryloxy-2-propanols
US5597848A (en) Benzenesulfonamide derivatives and use thereof
US5451606A (en) Anthraquinone compounds useful to treat osteoarticular conditions, pharmaceutical compositions and method of treatment
EP0486385B1 (de) Imidazol-Derivate, Verfahren zu deren Herstellung und diese enthaltende Zusammenstellungen
JPH01186866A (ja) 分割化アミノピロリジン神経防護剤
Carretero et al. A sulfinyl trialkoxycarbonyl ethene as a new enantiopure dienophile in asymmetric diels-alder reactions
FR2510575A1 (fr) Nouveaux composes bicycliques, leur procede de preparation et composition pharmaceutique les renfermant
US5990104A (en) Polycyclic alcaloid-derivatives as NMDA-receptor antagonists
BG64050B1 (bg) Метод за получаване на аминопроизводни на алкилоксифуранон, съединения, получени по този метод, и тяхното използване
HU180248B (en) Process for producing cyclohexydine derivatives
EP0268256A2 (de) 12-Halogenierte Forskolin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP0145591B1 (de) Pyrrolo(3,2,1-hi)indolderivate, ihre Herstellung und ihre therapeutische Anwendung
CA1183849A (fr) ¬alkyl- et alcenyl-3 piperidyl-4)-2 ethyl|-3 indoles et leur utilisation comme medicaments
EP0103500B1 (de) Phenethyl-1-alpha-phenyl-piperidin-3-propannitril-Derivate, ihre Herstellung und therapeutische Verwendung
LU87945A1 (fr) Derive de la dichloroaniline
US4524076A (en) Novel γ-aminobutyric acid transaminase inhibitors
JP2905931B2 (ja) 光学活性2―シクロペンテノン類の製造法

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: AKZO N.V.