FI64803C - Foerfarande foer framstaellning av antibakteriellt verkande 7-2-alkoxi-imino-2-furylacetamido)-3-(1-karboxialkyltetrazo ly-5-tiometyl)-3-cefem-4-karboxylsyror - Google Patents

Foerfarande foer framstaellning av antibakteriellt verkande 7-2-alkoxi-imino-2-furylacetamido)-3-(1-karboxialkyltetrazo ly-5-tiometyl)-3-cefem-4-karboxylsyror Download PDF

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Publication number
FI64803C
FI64803C FI772549A FI772549A FI64803C FI 64803 C FI64803 C FI 64803C FI 772549 A FI772549 A FI 772549A FI 772549 A FI772549 A FI 772549A FI 64803 C FI64803 C FI 64803C
Authority
FI
Finland
Prior art keywords
cooh
acid
formula
solution
thiomethyl
Prior art date
Application number
FI772549A
Other languages
English (en)
Finnish (fi)
Other versions
FI772549A (fi
FI64803B (fi
Inventor
William J Gottstein
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI772549A publication Critical patent/FI772549A/fi
Application granted granted Critical
Publication of FI64803B publication Critical patent/FI64803B/fi
Publication of FI64803C publication Critical patent/FI64803C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C265/00Derivatives of isocyanic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI772549A 1976-08-30 1977-08-26 Foerfarande foer framstaellning av antibakteriellt verkande 7-2-alkoxi-imino-2-furylacetamido)-3-(1-karboxialkyltetrazo ly-5-tiometyl)-3-cefem-4-karboxylsyror FI64803C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71902576A 1976-08-30 1976-08-30
US71902576 1976-08-30

Publications (3)

Publication Number Publication Date
FI772549A FI772549A (fi) 1978-03-01
FI64803B FI64803B (fi) 1983-09-30
FI64803C true FI64803C (fi) 1984-01-10

Family

ID=24888488

Family Applications (1)

Application Number Title Priority Date Filing Date
FI772549A FI64803C (fi) 1976-08-30 1977-08-26 Foerfarande foer framstaellning av antibakteriellt verkande 7-2-alkoxi-imino-2-furylacetamido)-3-(1-karboxialkyltetrazo ly-5-tiometyl)-3-cefem-4-karboxylsyror

Country Status (18)

Country Link
JP (1) JPS5331693A (da)
AU (1) AU510280B2 (da)
BE (1) BE858112A (da)
CA (1) CA1115267A (da)
CH (1) CH638812A5 (da)
DE (1) DE2739080A1 (da)
DK (1) DK382977A (da)
ES (1) ES461983A1 (da)
FI (1) FI64803C (da)
FR (1) FR2372167A1 (da)
GB (1) GB1557423A (da)
GR (1) GR74023B (da)
IE (1) IE46431B1 (da)
LU (1) LU78027A1 (da)
NL (1) NL7709466A (da)
SE (1) SE7709646L (da)
YU (1) YU204877A (da)
ZA (1) ZA775193B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
FI782683A (fi) * 1978-07-19 1980-01-20 Hoffmann La Roche Kefalosporinestrar och -estrar
US4973107A (en) * 1989-11-01 1990-11-27 Graham John M Dual pressure air brake system
EP1379531A2 (en) * 2001-04-19 2004-01-14 Bioferma Murcia, S.A. Enzymatic process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
NZ182649A (en) * 1975-11-27 1979-11-01 Beecham Group Ltd Cephalosporins,intermediates, and phrmaceutical compositions
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins

Also Published As

Publication number Publication date
NL7709466A (nl) 1978-03-02
DK382977A (da) 1978-03-01
IE771799L (en) 1978-02-28
BE858112A (fr) 1978-02-27
IE46431B1 (en) 1983-06-15
FR2372167B1 (da) 1981-11-27
AU510280B2 (en) 1980-06-19
DE2739080A1 (de) 1978-03-02
GB1557423A (en) 1979-12-12
JPS5331693A (en) 1978-03-25
FI772549A (fi) 1978-03-01
CH638812A5 (en) 1983-10-14
ES461983A1 (es) 1978-12-01
CA1115267A (en) 1981-12-29
AU2797277A (en) 1979-02-22
FR2372167A1 (fr) 1978-06-23
GR74023B (da) 1984-06-06
YU204877A (en) 1982-10-31
ZA775193B (en) 1978-07-26
SE7709646L (sv) 1978-03-01
FI64803B (fi) 1983-09-30
LU78027A1 (da) 1978-04-27

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MM Patent lapsed

Owner name: BRISTOL-MYERS CO