FI64359C - Analogifoerfarande foer framstaellning av terapeutiskt verksamma 3,4-dihydro-4-oxo-kinazolinderivat - Google Patents

Analogifoerfarande foer framstaellning av terapeutiskt verksamma 3,4-dihydro-4-oxo-kinazolinderivat Download PDF

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Publication number
FI64359C
FI64359C FI763391A FI763391A FI64359C FI 64359 C FI64359 C FI 64359C FI 763391 A FI763391 A FI 763391A FI 763391 A FI763391 A FI 763391A FI 64359 C FI64359 C FI 64359C
Authority
FI
Finland
Prior art keywords
dihydro
carboxy
oxo
formula
phenyl
Prior art date
Application number
FI763391A
Other languages
English (en)
Finnish (fi)
Other versions
FI763391A (xx
FI64359B (fi
Inventor
Cianfederico Doria
Ciriaco Romeo
Piernicola Giraldi
Francesco Lauria
Maria Luisa Corno
Piero Sberze
Marcello Tibolla
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI763391A publication Critical patent/FI763391A/fi
Application granted granted Critical
Publication of FI64359B publication Critical patent/FI64359B/fi
Publication of FI64359C publication Critical patent/FI64359C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/93—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI763391A 1975-12-05 1976-11-25 Analogifoerfarande foer framstaellning av terapeutiskt verksamma 3,4-dihydro-4-oxo-kinazolinderivat FI64359C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT29998/75A IT1050750B (it) 1975-12-05 1975-12-05 Derivati della 3.4 di idro chinazolina
IT2999875 1975-12-05

Publications (3)

Publication Number Publication Date
FI763391A FI763391A (xx) 1977-06-06
FI64359B FI64359B (fi) 1983-07-29
FI64359C true FI64359C (fi) 1983-11-10

Family

ID=11228830

Family Applications (1)

Application Number Title Priority Date Filing Date
FI763391A FI64359C (fi) 1975-12-05 1976-11-25 Analogifoerfarande foer framstaellning av terapeutiskt verksamma 3,4-dihydro-4-oxo-kinazolinderivat

Country Status (22)

Country Link
US (1) US4251531A (xx)
JP (1) JPS5271485A (xx)
AT (1) AT355029B (xx)
AU (1) AU505660B2 (xx)
BE (1) BE848696A (xx)
CA (1) CA1084051A (xx)
CH (2) CH626073A5 (xx)
CS (1) CS194786B2 (xx)
DE (1) DE2654215A1 (xx)
DK (1) DK147855C (xx)
FI (1) FI64359C (xx)
FR (1) FR2333511A1 (xx)
GB (1) GB1523081A (xx)
HU (1) HU177817B (xx)
IL (1) IL50849A (xx)
IT (1) IT1050750B (xx)
NL (1) NL7613450A (xx)
NO (1) NO146095C (xx)
NZ (1) NZ182778A (xx)
SE (1) SE7613588L (xx)
SU (1) SU786894A3 (xx)
ZA (1) ZA766745B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
JPS5925224U (ja) * 1982-08-10 1984-02-16 株式会社根来 かばん
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
GB8827988D0 (en) * 1988-11-30 1989-01-05 Smith Kline French Lab Chemical compounds
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
WO1999061406A2 (en) * 1998-05-22 1999-12-02 Abbott Laboratories Antiangiogenic drug to treat cancer, arthritis and retinopathy
US6632961B1 (en) 1998-05-22 2003-10-14 Abbott Laboratories Antiangiogenic drug to treat cancer, arthritis and retinopathy
CO5170498A1 (es) * 1999-05-28 2002-06-27 Abbott Lab Biaril sulfonamidas son utiles como inhibidores de proliferacion celular
AU2002257195A1 (en) * 2001-04-23 2002-11-05 University Of Virginia Patent Foundation Synthesis and evaluation of novel phthalimide mimics as anti-angiogenic agents
CN100518740C (zh) * 2003-06-06 2009-07-29 阿里克斯股份公司 杂环化合物作为scce抑制剂的制药用途
KR101099409B1 (ko) * 2003-06-06 2011-12-27 아렉시스 악티에볼라그 피부 상태 또는 암 치료를 위한 ｓｃｃｅ 저해제로서의융합된 헤테로사이클 화합물의 용도
CA2659967C (en) * 2006-08-08 2014-05-13 Aska Pharmaceutical Co., Ltd. Quinazoline derivatives
PL2118074T3 (pl) 2007-02-01 2014-06-30 Resverlogix Corp Związki chemiczne do celów profilaktyki i leczenia chorób układu sercowo-naczyniowego
EP2408454A2 (en) 2009-03-18 2012-01-25 Resverlogix Corp. Novel anti-inflammatory agents
JP5813626B2 (ja) 2009-04-22 2015-11-17 レスバーロジックス コーポレイション 新規抗炎症剤
JO3789B1 (ar) 2015-03-13 2021-01-31 Resverlogix Corp التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة
GB201510254D0 (en) * 2015-06-12 2015-07-29 Syngenta Participations Ag Improvements in or relating to organic compounds
CA3105174A1 (en) * 2018-06-27 2020-01-02 Reborna Biosciences, Inc. Prophylactic or therapeutic agent for spinal muscular atrophy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3696102A (en) * 1970-03-09 1972-10-03 Pfizer & Co C Process for the synthesis of substituted quinazolin-4-ones

Also Published As

Publication number Publication date
NL7613450A (nl) 1977-06-07
DK147855B (da) 1984-12-24
NZ182778A (en) 1978-07-28
DK147855C (da) 1985-06-10
FR2333511B1 (xx) 1979-03-02
IL50849A (en) 1980-11-30
ATA894376A (de) 1979-07-15
SE7613588L (sv) 1977-06-06
ZA766745B (en) 1977-10-26
GB1523081A (en) 1978-08-31
AU1947276A (en) 1978-05-18
SU786894A3 (ru) 1980-12-07
NO146095B (no) 1982-04-19
US4251531A (en) 1981-02-17
NO764135L (xx) 1977-06-07
AU505660B2 (en) 1979-11-29
CS194786B2 (en) 1979-12-31
CA1084051A (en) 1980-08-19
AT355029B (de) 1980-02-11
FI763391A (xx) 1977-06-06
DE2654215A1 (de) 1977-06-16
CH626073A5 (xx) 1981-10-30
NO146095C (no) 1982-08-11
DK546776A (da) 1977-06-06
FI64359B (fi) 1983-07-29
HU177817B (en) 1981-12-28
IL50849A0 (en) 1977-01-31
CH626075A5 (xx) 1981-10-30
JPS5271485A (en) 1977-06-14
JPS5543464B2 (xx) 1980-11-06
IT1050750B (it) 1981-03-20
BE848696A (fr) 1977-03-16
FR2333511A1 (fr) 1977-07-01

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Legal Events

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MM Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A