FI64143C - Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin - Google Patents

Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin Download PDF

Info

Publication number
FI64143C
FI64143C FI773273A FI773273A FI64143C FI 64143 C FI64143 C FI 64143C FI 773273 A FI773273 A FI 773273A FI 773273 A FI773273 A FI 773273A FI 64143 C FI64143 C FI 64143C
Authority
FI
Finland
Prior art keywords
compound
formula
fluoro
piperazinyl
therapeutic
Prior art date
Application number
FI773273A
Other languages
English (en)
Finnish (fi)
Other versions
FI773273A (fi
FI64143B (fi
Inventor
Fritz Hunziker
Rudolf Fischer
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI773273A publication Critical patent/FI773273A/fi
Application granted granted Critical
Publication of FI64143B publication Critical patent/FI64143B/fi
Publication of FI64143C publication Critical patent/FI64143C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI773273A 1976-11-10 1977-11-01 Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin FI64143C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1415776A CH624682A5 (US07923587-20110412-C00022.png) 1976-11-10 1976-11-10
CH1415776 1976-11-10

Publications (3)

Publication Number Publication Date
FI773273A FI773273A (fi) 1978-05-11
FI64143B FI64143B (fi) 1983-06-30
FI64143C true FI64143C (fi) 1983-10-10

Family

ID=4398460

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773273A FI64143C (fi) 1976-11-10 1977-11-01 Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin

Country Status (26)

Country Link
US (1) US4308207A (US07923587-20110412-C00022.png)
JP (1) JPS5929076B2 (US07923587-20110412-C00022.png)
AT (1) AT366682B (US07923587-20110412-C00022.png)
AU (1) AU517829B2 (US07923587-20110412-C00022.png)
BE (1) BE860613A (US07923587-20110412-C00022.png)
CA (1) CA1086315A (US07923587-20110412-C00022.png)
CH (1) CH624682A5 (US07923587-20110412-C00022.png)
CY (1) CY1269A (US07923587-20110412-C00022.png)
DE (1) DE2748920C2 (US07923587-20110412-C00022.png)
DK (1) DK140724B (US07923587-20110412-C00022.png)
ES (1) ES463971A1 (US07923587-20110412-C00022.png)
FI (1) FI64143C (US07923587-20110412-C00022.png)
FR (1) FR2370745A1 (US07923587-20110412-C00022.png)
GB (2) GB1592329A (US07923587-20110412-C00022.png)
HK (1) HK32282A (US07923587-20110412-C00022.png)
IE (1) IE46262B1 (US07923587-20110412-C00022.png)
IL (1) IL53332A (US07923587-20110412-C00022.png)
KE (1) KE3472A (US07923587-20110412-C00022.png)
MY (1) MY8400056A (US07923587-20110412-C00022.png)
NL (1) NL175297C (US07923587-20110412-C00022.png)
NZ (2) NZ185642A (US07923587-20110412-C00022.png)
PH (1) PH13515A (US07923587-20110412-C00022.png)
PT (1) PT67247B (US07923587-20110412-C00022.png)
SE (1) SE435510B (US07923587-20110412-C00022.png)
SG (1) SG66584G (US07923587-20110412-C00022.png)
SU (1) SU686616A3 (US07923587-20110412-C00022.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3402060A1 (de) * 1984-01-21 1985-08-01 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
US5416087A (en) * 1990-10-10 1995-05-16 Wong; Jesse K. Bis-benzo, cyclohepta piperidylidene, piperidine and piperazine compounds, compositions and methods of use
WO2004026030A2 (en) * 2002-09-18 2004-04-01 Fmc Corporation Insecticidal tricyclic derivatives
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
MXPA05007784A (es) * 2003-01-23 2005-09-30 Acadia Pharm Inc Empleo de la n-desmetilclozapina para tratar las enfermedades neuropsiquiatricas humanas.
CN101962369A (zh) * 2003-12-22 2011-02-02 阿卡蒂亚药品公司 氨基取代的二芳基[a,d]环庚烯类似物作为毒蕈碱激动剂的用途及神经精神疾病的治疗方法
CN1950346A (zh) * 2004-04-01 2007-04-18 阿卡蒂亚药品公司 N-去甲基氯氮平的晶形
US20070105836A1 (en) * 2005-10-31 2007-05-10 Lars Pettersson Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL140242B (nl) * 1963-03-01 1973-11-15 Wander Ag Dr A Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen.
US3389139A (en) * 1963-06-14 1968-06-18 Wander Ag Dr A 6-homopiperazino and piperazinomorphanthridines
GB1006156A (en) * 1963-06-14 1965-09-29 Wander Ag Dr A 6-basic substituted morphanthridines
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
US3962248A (en) * 1972-04-04 1976-06-08 Sandoz, Inc. Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
CH601287A5 (US07923587-20110412-C00022.png) * 1975-08-06 1978-07-14 Sandoz Ag

Also Published As

Publication number Publication date
KE3472A (en) 1984-11-09
DK485677A (US07923587-20110412-C00022.png) 1978-05-11
IE46262L (en) 1978-05-10
DK140724B (da) 1979-11-05
NL7712171A (nl) 1978-05-12
AU3046777A (en) 1979-05-17
SE7712387L (sv) 1978-05-11
FI773273A (fi) 1978-05-11
BE860613A (fr) 1978-05-08
IL53332A (en) 1981-11-30
PT67247A (en) 1977-12-01
SE435510B (sv) 1984-10-01
DK140724C (US07923587-20110412-C00022.png) 1980-03-31
JPS5359686A (en) 1978-05-29
PT67247B (en) 1979-11-12
CA1086315A (en) 1980-09-23
SG66584G (en) 1985-03-15
PH13515A (en) 1980-06-03
NL175297C (nl) 1984-10-16
JPS5929076B2 (ja) 1984-07-18
CY1269A (en) 1984-11-23
ATA799177A (de) 1981-09-15
CH624682A5 (US07923587-20110412-C00022.png) 1981-08-14
NZ191043A (en) 1980-09-12
FR2370745B1 (US07923587-20110412-C00022.png) 1980-08-22
FR2370745A1 (fr) 1978-06-09
ES463971A1 (es) 1978-12-01
DE2748920C2 (de) 1982-12-02
US4308207A (en) 1981-12-29
SU686616A1 (en) 1979-09-15
IL53332A0 (en) 1978-01-31
IE46262B1 (en) 1983-04-20
NL175297B (nl) 1984-05-16
DE2748920A1 (de) 1978-05-11
SU686616A3 (ru) 1979-09-15
HK32282A (en) 1982-07-23
FI64143B (fi) 1983-06-30
AU517829B2 (en) 1981-08-27
AT366682B (de) 1982-04-26
NZ185642A (en) 1980-09-12
GB1592329A (en) 1981-07-08
GB1592330A (en) 1981-07-08
MY8400056A (en) 1984-12-31

Similar Documents

Publication Publication Date Title
NO791150L (no) Substituerte 5,6-dimetylpyrrolo/2,3-d/pyrimidiner, fremgangsmaate til deres fremstilling og deres anvendelse som legemiddel
Thompson et al. Synthesis and pharmacological evaluation of a series of dibenzo [a, d] cycloalkenimines as N-methyl-D-aspartate antagonists
FI64143C (fi) Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin
CS273193B2 (en) Method of new tetrahydrofuro- and -thienol (2,3-c) pyridine production
CA1074799A (en) Process for the production of basically substituted alkoxypyridinecarboxamides
US3763142A (en) Thiazolodiazepines
Koebel et al. Synthesis of thieno [2, 3-b] azepin-4-ones as potential antineoplastic agents
FI64939B (fi) Foerfarande foer framstaellning av en 10,11-dihydro-5h-dibenso(a,d)cyklohepten-5,10-imin
US4148903A (en) Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines
US4406900A (en) Neuroleptic use of morphanthridines
US3657245A (en) Certain 5h 8h-thiazolo(3 2-a)pyrrolo(2 3-d)pyrimidin-5-ones
US3681355A (en) Ergonarcarnines
US3759943A (en) Amido and amino triazolo benzodiazepines
US3890350A (en) 3-Amino-2-(methylenedioxyphenyl)-acroleins
GB1595606A (en) N-9,10-dihydrolysergyl-m-aminobenzoic acid amides and related compounds
US3917833A (en) Amino-substituted benzocycloheptenones for inducing sleep
US4452982A (en) Process for the preparation of nitrogen-bridgehead condensed pyrimidine compounds, and pharmaceutical compositions containing them
US3737544A (en) Compositions and methods utilizing 2,5-dimethyl-1,3,4,9b-tetrahydo-2h-indeno (1,2-c)pyridine
Lancelot et al. A Novel Synthesis of 2, 3-dihydro [1, 5] benzothiazepin-4 (5h)-ones
IE44449B1 (en) 11-methylene-6-piperazinyl-morphanthridine derivatives
IE45811B1 (en) Anthelmintic compounds
GB2154584A (en) Diazepinoindoles
IE46688B1 (en) N-(2,3 -dihydro-9-ergolen-8 -yl methyl)ureas
US3857854A (en) 6-phenyl-1h,4h-{8 1,2,4{9 oxadiazalo{8 4,3-2{9 {8 1,4{9 benzodiazepin-1-ones
US3671512A (en) 6-amino-3-pyridinesulfonamides

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SANDOZ AG