FI62064C - Foerfarande foer framstaellning av nya 2,6-disubstituerade fenylaminoguanidinfoereningar vilka aer anvaendbara saosom blodtrycknedsaettande laekemedel - Google Patents

Foerfarande foer framstaellning av nya 2,6-disubstituerade fenylaminoguanidinfoereningar vilka aer anvaendbara saosom blodtrycknedsaettande laekemedel Download PDF

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Publication number
FI62064C
FI62064C FI3243/74A FI324374A FI62064C FI 62064 C FI62064 C FI 62064C FI 3243/74 A FI3243/74 A FI 3243/74A FI 324374 A FI324374 A FI 324374A FI 62064 C FI62064 C FI 62064C
Authority
FI
Finland
Prior art keywords
alkyl
group
hydrogen
compound
formula
Prior art date
Application number
FI3243/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI324374A (xx
FI62064B (fi
Inventor
Harm Jan Panneman
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI324374A publication Critical patent/FI324374A/fi
Application granted granted Critical
Publication of FI62064B publication Critical patent/FI62064B/fi
Publication of FI62064C publication Critical patent/FI62064C/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16Compounds containing any of the groups, e.g. aminoguanidine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI3243/74A 1973-11-09 1974-11-07 Foerfarande foer framstaellning av nya 2,6-disubstituerade fenylaminoguanidinfoereningar vilka aer anvaendbara saosom blodtrycknedsaettande laekemedel FI62064C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7315350 1973-11-09
NL7315350A NL7315350A (nl) 1973-11-09 1973-11-09 Nieuwe aminoguanidine verbindingen.

Publications (3)

Publication Number Publication Date
FI324374A FI324374A (xx) 1975-05-10
FI62064B FI62064B (fi) 1982-07-30
FI62064C true FI62064C (fi) 1982-11-10

Family

ID=19819967

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3243/74A FI62064C (fi) 1973-11-09 1974-11-07 Foerfarande foer framstaellning av nya 2,6-disubstituerade fenylaminoguanidinfoereningar vilka aer anvaendbara saosom blodtrycknedsaettande laekemedel

Country Status (17)

Country Link
US (1) US3972932A (xx)
JP (1) JPS5546389B2 (xx)
AR (1) AR205358A1 (xx)
BE (1) BE822019A (xx)
CA (1) CA1032962A (xx)
CH (1) CH616656A5 (xx)
DE (1) DE2452691A1 (xx)
DK (1) DK138791B (xx)
ES (1) ES431775A1 (xx)
FI (1) FI62064C (xx)
FR (1) FR2250521B1 (xx)
GB (1) GB1487852A (xx)
HU (1) HU171856B (xx)
IE (1) IE40409B1 (xx)
NL (1) NL7315350A (xx)
SE (1) SE420720B (xx)
ZA (1) ZA746701B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141992A (en) * 1975-08-22 1979-02-27 American Cyanamid Company Cycloalkylcarboxyamidines and halobenzamidines as anti-amebic agents
US4113776A (en) * 1976-04-15 1978-09-12 Hoffmann-La Roche Inc. 1-(2-Aminoethyl)-3-(2,6-dihalophenyl)guanidines
JPS5930330A (ja) * 1982-08-12 1984-02-17 Yaesu Musen Co Ltd デジタル周波数表示方式
HU190639B (en) * 1983-12-12 1986-09-29 Gyogyszerkutato Intezet Kv,Hu Process for production of new aminoguanidin derivatives
ZA857153B (en) * 1984-09-19 1986-05-28 Ciba Geigy Ag Substituted carbodiimides
DE3581029D1 (de) * 1984-09-19 1991-02-07 Ciba Geigy Ag Substituierte carbodiimide.
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
ES2181668T3 (es) 1990-03-02 2003-03-01 Oregon State Guanidinas tri- y tetra-substituidas y su uso como antagonistas de aminoacido excitador.
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
KR100246083B1 (ko) * 1991-02-08 2000-03-15 버틀러 그레고리 비. 신경전달물질의 방출조절물질인 치환 구아니딘류 및 그것의 유도체와 그들을 함유하는 약학 조성물
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
ATE245977T1 (de) * 1993-05-27 2003-08-15 Cenes Ltd Therapeutische substituierte guanidine
CA2177081A1 (en) * 1993-11-23 1995-06-01 Graham J. Durant Therapeutic substituted guanidines
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
CA2182302A1 (en) 1994-02-03 1995-08-10 Stanley M. Goldin Therapeutic guanidines
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
JP4564786B2 (ja) * 2004-06-07 2010-10-20 株式会社日本ファインケム 1−置換―1―アミノグアニジン又はその塩、及びこれらの製造方法
JP4739695B2 (ja) * 2004-06-07 2011-08-03 株式会社日本ファインケム 5−アミノ―1―置換―1,2,4―トリアゾールの製造方法、及び該製造方法で得られるトリアゾール誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB800869A (en) * 1955-09-28 1958-09-03 Ici Ltd Substituted amino-guanidines
NL7011683A (xx) * 1970-08-07 1972-02-09

Also Published As

Publication number Publication date
JPS5546389B2 (xx) 1980-11-22
HU171856B (hu) 1978-04-28
FR2250521B1 (xx) 1979-03-16
US3972932A (en) 1976-08-03
JPS5077328A (xx) 1975-06-24
ZA746701B (en) 1975-11-26
IE40409L (en) 1975-05-09
DE2452691A1 (de) 1975-05-15
IE40409B1 (en) 1979-05-23
CH616656A5 (xx) 1980-04-15
NL7315350A (nl) 1975-05-13
SE7414045L (xx) 1975-05-12
DK138791C (xx) 1979-04-09
CA1032962A (en) 1978-06-13
DK579774A (xx) 1975-07-07
FR2250521A1 (xx) 1975-06-06
FI324374A (xx) 1975-05-10
ES431775A1 (es) 1976-12-16
FI62064B (fi) 1982-07-30
BE822019A (fr) 1975-05-09
DK138791B (da) 1978-10-30
AR205358A1 (es) 1976-04-30
GB1487852A (en) 1977-10-05
SE420720B (sv) 1981-10-26

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