FI57933C - Foerfarande foer framstaellning av terapeutiskt aktiva olefina arylketoner - Google Patents

Foerfarande foer framstaellning av terapeutiskt aktiva olefina arylketoner Download PDF

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Publication number
FI57933C
FI57933C FI3573/72A FI357372A FI57933C FI 57933 C FI57933 C FI 57933C FI 3573/72 A FI3573/72 A FI 3573/72A FI 357372 A FI357372 A FI 357372A FI 57933 C FI57933 C FI 57933C
Authority
FI
Finland
Prior art keywords
fluorophenyl
hydroxypiperidine
hydroxy
halogen
butynyl
Prior art date
Application number
FI3573/72A
Other languages
English (en)
Finnish (fi)
Other versions
FI57933B (fi
Inventor
Junki Katsube
Masaru Nakao
Kikuo Sasajima
Isamu Maruyama
Masaharu Takayama
Keiichi Ono
Shigenari Katayama
Yoshihiro Tanaka
Shigeho Inaba
Hisao Yamamoto
Izumi Yanagihara
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP46102855A external-priority patent/JPS5812273B2/ja
Priority claimed from JP46102854A external-priority patent/JPS5820956B2/ja
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Application granted granted Critical
Publication of FI57933B publication Critical patent/FI57933B/fi
Publication of FI57933C publication Critical patent/FI57933C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
FI3573/72A 1971-12-18 1972-12-15 Foerfarande foer framstaellning av terapeutiskt aktiva olefina arylketoner FI57933C (fi)

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
JP10285471 1971-12-18
JP10285571 1971-12-18
JP46102855A JPS5812273B2 (ja) 1971-12-18 1971-12-18 シンキ アセチレンアルコ−ルユウドウタイ ノ シンキセイゾウホウ
JP46102854A JPS5820956B2 (ja) 1971-12-18 1971-12-18 シンキナル アセチレンケトンユウドウタイ ノ シンキセイゾウホウ
JP1616972A JPS5544749B2 (ja) 1971-12-18 1972-02-15
JP1616972 1972-02-15
JP1675272 1972-02-17
JP1675272A JPS5535390B2 (ja) 1971-12-18 1972-02-17
JP47043125A JPS491530A (ja) 1971-12-18 1972-04-28
JP4312572 1972-04-28
JP6520872 1972-06-28
JP47065208A JPS4924932A (ja) 1971-12-18 1972-06-28
JP7026572 1972-07-12
JP47070265A JPS5820957B2 (ja) 1971-12-18 1972-07-12 シンキ ナル ブテノ−ルアミンユウドウタイ ノ シンキセイゾウホウ
JP7026672 1972-07-12
JP47070266A JPS5839826B2 (ja) 1971-12-18 1972-07-12 シンキナルオレフイニツクアミノケトンユウドウタイ ノ シンキセイゾウホウ
JP9572072 1972-09-22
JP47095720A JPS4961130A (ja) 1971-12-18 1972-09-22

Publications (2)

Publication Number Publication Date
FI57933B FI57933B (fi) 1980-07-31
FI57933C true FI57933C (fi) 1980-11-10

Family

ID=27576674

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3573/72A FI57933C (fi) 1971-12-18 1972-12-15 Foerfarande foer framstaellning av terapeutiskt aktiva olefina arylketoner

Country Status (9)

Country Link
JP (7) JPS5544749B2 (ja)
AU (1) AU470861B2 (ja)
BE (1) BE792906A (ja)
CH (2) CH589661A5 (ja)
FI (1) FI57933C (ja)
FR (1) FR2163717B1 (ja)
GB (1) GB1407706A (ja)
NL (1) NL7217236A (ja)
SE (1) SE399707B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50140451A (ja) * 1974-04-16 1975-11-11
JPS5116677A (ja) * 1974-07-29 1976-02-10 Sumitomo Chemical Co Shinkinabuchirofuenonjudotai oyobi sonosanfukaennoseiho
JPS5283863U (ja) * 1975-12-13 1977-06-22
JPS5324020A (en) * 1976-08-14 1978-03-06 Kumiai Chem Ind Co Ltd Composition for herbicide
JPS5498755A (en) * 1978-01-13 1979-08-03 Sumitomo Chem Co Ltd Novel butenophenone derivative
CA1151164A (en) * 1978-01-13 1983-08-02 Atsuyuki Kojima Conjugated ketone compounds and their production and use
JPS55116000U (ja) * 1979-02-10 1980-08-15
US4728659A (en) * 1984-06-27 1988-03-01 Ss Pharmaceutical Co., Ltd. Aminomethyl derivatives and preparation process thereof as well as platelet aggregation inhibitors containing same
US5703088A (en) * 1989-08-21 1997-12-30 Beth Israel Deaconess Medical Center, Inc. Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses
US5244902A (en) * 1989-08-21 1993-09-14 Beth Israel Hospital Association Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses
DE69130216T2 (de) * 1990-03-16 1999-03-25 The Beth Israel Hospital Association, Boston, Mass. Verwendung von spiperon als immunsuppressivum und antiinflammatorisches mittel
US5693645A (en) * 1992-12-23 1997-12-02 Beth Israel Deaconess Medical Center, Inc. Use of spiperone or spiperone derivatives as immunosuppressant agents
US11707027B2 (en) 2019-12-02 2023-07-25 Fork Farms Holdings, Llc Hydroponic grow assembly

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK131147B (da) * 1969-10-27 1975-06-02 Sumitomo Chemical Co Fremgangsmåde til fremstilling af butyrophenonderivater eller syreadditionssalte deraf.
BE758380A (fr) * 1969-11-04 1971-04-16 Sumitomo Chemical Co Procede de preparation de derives d'aryl-cetones

Also Published As

Publication number Publication date
GB1407706A (en) 1975-09-24
JPS4885569A (ja) 1973-11-13
SE399707B (sv) 1978-02-27
JPS4881854A (ja) 1973-11-01
FR2163717A1 (ja) 1973-07-27
JPS5535390B2 (ja) 1980-09-12
JPS4961130A (ja) 1974-06-13
CH593296A5 (ja) 1977-11-30
JPS4924932A (ja) 1974-03-05
AU470861B2 (en) 1974-06-20
JPS4930335A (ja) 1974-03-18
FR2163717B1 (ja) 1977-07-15
FI57933B (fi) 1980-07-31
JPS491530A (ja) 1974-01-08
JPS5820957B2 (ja) 1983-04-26
JPS5544749B2 (ja) 1980-11-13
JPS4930336A (ja) 1974-03-18
JPS5839826B2 (ja) 1983-09-01
NL7217236A (ja) 1973-06-20
AU5023172A (en) 1974-06-20
BE792906A (fr) 1973-06-18
CH589661A5 (ja) 1977-07-15

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