FI57413C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 3-(2-(4-(2-substituerad-10,11-dihydro-dibenso(b,f)tiepin-10-yl)-1-piperazinyl)-etyl)-2-oxazolidinoner - Google Patents
Foerfarande foer framstaellning av terapeutiskt anvaendbara 3-(2-(4-(2-substituerad-10,11-dihydro-dibenso(b,f)tiepin-10-yl)-1-piperazinyl)-etyl)-2-oxazolidinoner Download PDFInfo
- Publication number
- FI57413C FI57413C FI224873A FI224873A FI57413C FI 57413 C FI57413 C FI 57413C FI 224873 A FI224873 A FI 224873A FI 224873 A FI224873 A FI 224873A FI 57413 C FI57413 C FI 57413C
- Authority
- FI
- Finland
- Prior art keywords
- acid
- thiepin
- dihydro
- formula
- piperazinyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 7
- 230000001225 therapeutic effect Effects 0.000 title 2
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- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 229940071870 hydroiodic acid Drugs 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 150000002440 hydroxy compounds Chemical class 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 150000002688 maleic acid derivatives Chemical class 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 150000002763 monocarboxylic acids Chemical class 0.000 description 1
- 231100000189 neurotoxic Toxicity 0.000 description 1
- 230000002887 neurotoxic effect Effects 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- GEVPUGOOGXGPIO-UHFFFAOYSA-N oxalic acid;dihydrate Chemical compound O.O.OC(=O)C(O)=O GEVPUGOOGXGPIO-UHFFFAOYSA-N 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 229920000137 polyphosphoric acid Polymers 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- NNFCIKHAZHQZJG-UHFFFAOYSA-N potassium cyanide Chemical compound [K+].N#[C-] NNFCIKHAZHQZJG-UHFFFAOYSA-N 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 230000003578 releasing effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000010288 sodium nitrite Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 238000000967 suction filtration Methods 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- BISQTCXKVNCDDA-UHFFFAOYSA-N thiepine Chemical compound S1C=CC=CC=C1 BISQTCXKVNCDDA-UHFFFAOYSA-N 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1100172A CH569013A5 (en)) | 1972-07-21 | 1972-07-21 | |
| CH1100172 | 1972-07-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI57413B FI57413B (fi) | 1980-04-30 |
| FI57413C true FI57413C (fi) | 1980-08-11 |
Family
ID=4369013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI224873A FI57413C (fi) | 1972-07-21 | 1973-07-16 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 3-(2-(4-(2-substituerad-10,11-dihydro-dibenso(b,f)tiepin-10-yl)-1-piperazinyl)-etyl)-2-oxazolidinoner |
Country Status (8)
| Country | Link |
|---|---|
| DD (1) | DD111908A5 (en)) |
| FI (1) | FI57413C (en)) |
| HU (1) | HU168042B (en)) |
| IE (1) | IE37914B1 (en)) |
| IL (1) | IL42585A0 (en)) |
| NO (1) | NO138695C (en)) |
| SU (1) | SU490287A3 (en)) |
| ZA (1) | ZA734176B (en)) |
-
1973
- 1973-06-20 ZA ZA734176A patent/ZA734176B/xx unknown
- 1973-06-22 IL IL42585A patent/IL42585A0/xx unknown
- 1973-07-16 IE IE119373A patent/IE37914B1/xx unknown
- 1973-07-16 FI FI224873A patent/FI57413C/fi active
- 1973-07-19 DD DD17236773A patent/DD111908A5/xx unknown
- 1973-07-19 HU HUHO001596 patent/HU168042B/hu unknown
- 1973-07-20 NO NO296373A patent/NO138695C/no unknown
- 1973-07-20 SU SU1943851A patent/SU490287A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| SU490287A3 (ru) | 1975-10-30 |
| NO138695C (no) | 1978-10-25 |
| DD111908A5 (en)) | 1975-03-12 |
| FI57413B (fi) | 1980-04-30 |
| IL42585A0 (en) | 1973-08-29 |
| IE37914B1 (en) | 1977-11-09 |
| IE37914L (en) | 1974-01-21 |
| ZA734176B (en) | 1974-03-27 |
| NO138695B (no) | 1978-07-17 |
| HU168042B (en)) | 1976-02-28 |
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