FI57110C - Foerfarande foer framstaellning av trifluormetylmerkaptoacetamidocefalosporiner med antibakteriell verkan - Google Patents
Foerfarande foer framstaellning av trifluormetylmerkaptoacetamidocefalosporiner med antibakteriell verkan Download PDFInfo
- Publication number
- FI57110C FI57110C FI2252/73A FI225273A FI57110C FI 57110 C FI57110 C FI 57110C FI 2252/73 A FI2252/73 A FI 2252/73A FI 225273 A FI225273 A FI 225273A FI 57110 C FI57110 C FI 57110C
- Authority
- FI
- Finland
- Prior art keywords
- acid
- cephem
- trifluoromethyl
- carboxylic acid
- ylthiomethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/28—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00273571A US3828037A (en) | 1972-07-20 | 1972-07-20 | Trifluoromethylmercaptoacetamidocephalosporins |
| US27357172 | 1972-07-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI57110B FI57110B (fi) | 1980-02-29 |
| FI57110C true FI57110C (fi) | 1980-06-10 |
Family
ID=23044497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI2252/73A FI57110C (fi) | 1972-07-20 | 1973-07-16 | Foerfarande foer framstaellning av trifluormetylmerkaptoacetamidocefalosporiner med antibakteriell verkan |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US3828037A (es) |
| JP (1) | JPS5919959B2 (es) |
| AR (1) | AR197514A1 (es) |
| AT (1) | AT324562B (es) |
| AU (1) | AU467469B2 (es) |
| BE (1) | BE802199A (es) |
| CA (1) | CA1023347A (es) |
| CH (1) | CH584227A5 (es) |
| CS (1) | CS168037B2 (es) |
| DD (1) | DD114088A5 (es) |
| DE (1) | DE2336345C2 (es) |
| ES (1) | ES416980A1 (es) |
| FI (1) | FI57110C (es) |
| FR (1) | FR2193574B1 (es) |
| GB (1) | GB1393348A (es) |
| HU (1) | HU169129B (es) |
| IE (1) | IE37916B1 (es) |
| IL (1) | IL42737A (es) |
| LU (1) | LU68041A1 (es) |
| NL (1) | NL7309869A (es) |
| PH (1) | PH9532A (es) |
| PL (1) | PL85513B1 (es) |
| SE (1) | SE416205B (es) |
| ZA (1) | ZA734129B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793448A (fr) * | 1971-12-31 | 1973-06-28 | Roussel Uclaf | Procede de preparation de nouveaux derives des cephalosporines et produits obtenus |
| US3898220A (en) * | 1972-07-20 | 1975-08-05 | Smithkline Corp | Trifluoromethylmercaptoacetamidocephalosporins |
| US3898221A (en) * | 1972-07-20 | 1975-08-05 | Smithkline Corp | Trifluoromethylmercaptoacetamidocephalosporins |
| US3943128A (en) * | 1973-06-18 | 1976-03-09 | Smithkline Corporation | 7-Trifluoromethylsulfinylacetamido cephalosporins |
| US3943127A (en) * | 1973-06-18 | 1976-03-09 | Smithkline Corporation | 7-Trifluoromethylsulfinylacetamido cephalosporins |
| US3880848A (en) * | 1973-06-18 | 1975-04-29 | Smithkline Corp | 7-Trifluorome thylsulfinylacetamido cephalosporins |
| US3998818A (en) * | 1973-12-26 | 1976-12-21 | Smithkline Corporation | Trifluoroethylmercapto, -sulfinyl or -sulfonyl acetamidocephalosporins |
| US3957770A (en) * | 1973-12-26 | 1976-05-18 | Smithkline Corporation | Substituted acetamidocephalosporins |
| US4013765A (en) * | 1973-12-26 | 1977-03-22 | Smithkline Corporation | Compositions and methods for treating bacterial infections with substituted acetamidocephalosporins |
| US3998819A (en) * | 1973-12-26 | 1976-12-21 | Smithkline Corporation | Trifluoroethyl-mercapto, -sulfinyl or -sulfonyl acetamidocephalosporins |
| US3907788A (en) * | 1974-03-01 | 1975-09-23 | American Home Prod | Sulfenyl derivatives of 7-aminocephalosporanic acid |
| US3965099A (en) * | 1974-06-26 | 1976-06-22 | Smithkline Corporation | Cephalosporin esters with antibacterial activity |
| US4286089A (en) * | 1974-12-27 | 1981-08-25 | Smithkline Corporation | 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins |
| DK586175A (da) * | 1974-12-28 | 1976-06-29 | Asahi Chemical Ind | Cephalosporin-forbindelser |
| US4093723A (en) * | 1976-05-19 | 1978-06-06 | Smithkline Corporation | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins |
| US4020057A (en) * | 1975-06-18 | 1977-04-26 | Smithkline Corporation | 7β-Acyloxy cephalosporins |
| US4025626A (en) * | 1975-12-09 | 1977-05-24 | Smithkline Corporation | 7-Acyl-3-(ureidoalkyl substituted tetrazolylthiomethyl)-cephalosporins |
| US4075338A (en) * | 1975-12-29 | 1978-02-21 | Smithkline Corporation | Substituted acetamidocephalosporins |
| US4041162A (en) * | 1976-03-11 | 1977-08-09 | Smithkline Corporation | 7-Acyl-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins |
| US4034092A (en) * | 1976-05-03 | 1977-07-05 | Smithkline Corporation | 7-Acyl-3-(carboxyalkyl and carbamoylalkyl substituted oxadiazolylthiomethyl) cephalosporins |
| US4058609A (en) * | 1976-06-28 | 1977-11-15 | Smithkline Corporation | 7-Dithioacetamido cephalosporins |
| US4223135A (en) * | 1979-03-19 | 1980-09-16 | Bristol-Myers Company | Production of cephalosporins |
| US4316016A (en) * | 1979-03-19 | 1982-02-16 | Bristol-Myers Company | Cephalosporin intermediates |
| US4316017A (en) * | 1979-03-19 | 1982-02-16 | Bristol-Myers Company | Cephalosporin intermediates |
| JPS57109761A (en) * | 1980-12-26 | 1982-07-08 | Shionogi & Co Ltd | Fluoromethylthioacetic acid compound and its preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3641021A (en) * | 1969-04-18 | 1972-02-08 | Lilly Co Eli | 3 7-(ring-substituted) cephalosporin compounds |
-
1972
- 1972-07-20 US US00273571A patent/US3828037A/en not_active Expired - Lifetime
-
1973
- 1973-06-19 ZA ZA734129A patent/ZA734129B/xx unknown
- 1973-07-06 GB GB3226173A patent/GB1393348A/en not_active Expired
- 1973-07-11 BE BE133356A patent/BE802199A/xx not_active IP Right Cessation
- 1973-07-13 IL IL42737A patent/IL42737A/en unknown
- 1973-07-13 SE SE7309853A patent/SE416205B/sv unknown
- 1973-07-16 PH PH14825*UA patent/PH9532A/en unknown
- 1973-07-16 NL NL7309869A patent/NL7309869A/xx not_active Application Discontinuation
- 1973-07-16 IE IE1197/73A patent/IE37916B1/xx unknown
- 1973-07-16 FI FI2252/73A patent/FI57110C/fi active
- 1973-07-17 DE DE2336345A patent/DE2336345C2/de not_active Expired
- 1973-07-17 ES ES416980A patent/ES416980A1/es not_active Expired
- 1973-07-18 FR FR7326268A patent/FR2193574B1/fr not_active Expired
- 1973-07-18 PL PL1973164143A patent/PL85513B1/pl unknown
- 1973-07-18 LU LU68041A patent/LU68041A1/xx unknown
- 1973-07-18 CA CA176,785A patent/CA1023347A/en not_active Expired
- 1973-07-18 JP JP48082606A patent/JPS5919959B2/ja not_active Expired
- 1973-07-19 HU HUSI1327A patent/HU169129B/hu unknown
- 1973-07-19 CH CH1060873A patent/CH584227A5/xx not_active IP Right Cessation
- 1973-07-19 AU AU58314/73A patent/AU467469B2/en not_active Expired
- 1973-07-20 DD DD172415A patent/DD114088A5/xx unknown
- 1973-07-20 AR AR249204A patent/AR197514A1/es active
- 1973-07-20 CS CS5237A patent/CS168037B2/cs unknown
- 1973-07-20 AT AT646873A patent/AT324562B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI57110B (fi) | 1980-02-29 |
| US3828037A (en) | 1974-08-06 |
| DE2336345C2 (de) | 1982-05-13 |
| PL85513B1 (es) | 1976-04-30 |
| DE2336345A1 (de) | 1974-02-07 |
| ES416980A1 (es) | 1976-03-01 |
| AU5831473A (en) | 1975-01-23 |
| LU68041A1 (es) | 1973-09-26 |
| IE37916L (en) | 1974-01-20 |
| BE802199A (fr) | 1974-01-11 |
| AR197514A1 (es) | 1974-04-15 |
| CA1023347A (en) | 1977-12-27 |
| CH584227A5 (es) | 1977-01-31 |
| IL42737A0 (en) | 1973-10-25 |
| PH9532A (en) | 1976-01-09 |
| GB1393348A (en) | 1975-05-07 |
| IE37916B1 (en) | 1977-11-09 |
| FR2193574A1 (es) | 1974-02-22 |
| FR2193574B1 (es) | 1977-07-15 |
| CS168037B2 (es) | 1976-05-28 |
| ZA734129B (en) | 1974-05-29 |
| JPS5919959B2 (ja) | 1984-05-09 |
| AU467469B2 (en) | 1975-12-04 |
| AT324562B (de) | 1975-09-10 |
| SE416205B (sv) | 1980-12-08 |
| JPS4943997A (es) | 1974-04-25 |
| NL7309869A (es) | 1974-01-22 |
| IL42737A (en) | 1977-03-31 |
| DD114088A5 (es) | 1975-07-12 |
| HU169129B (es) | 1976-09-28 |
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