FI55184B - Foerfarande foer framstaellning av terapeutiskt verksamma fenyl-2-pyrrolidinoner samt deras isomerer - Google Patents

Foerfarande foer framstaellning av terapeutiskt verksamma fenyl-2-pyrrolidinoner samt deras isomerer

Info

Publication number
FI55184B
FI55184B FI2068/71A FI206871A FI55184B FI 55184 B FI55184 B FI 55184B FI 2068/71 A FI2068/71 A FI 2068/71A FI 206871 A FI206871 A FI 206871A FI 55184 B FI55184 B FI 55184B
Authority
FI
Finland
Prior art keywords
verksamy
pyrrolidinoner
isomerer
framework
therapeutic
Prior art date
Application number
FI2068/71A
Other languages
English (en)
Other versions
FI55184C (fi
Inventor
Joseph Strubbe
Raymond Linz
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of FI55184B publication Critical patent/FI55184B/fi
Application granted granted Critical
Publication of FI55184C publication Critical patent/FI55184C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
FI2068/71A 1970-07-24 1971-07-21 Foerfarande foer framstaellning av terapeutiskt verksamma fenyl-2-pyrrolidinoner samt deras isomerer FI55184C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3594870 1970-07-24

Publications (2)

Publication Number Publication Date
FI55184B true FI55184B (fi) 1979-02-28
FI55184C FI55184C (fi) 1979-06-11

Family

ID=10383283

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2068/71A FI55184C (fi) 1970-07-24 1971-07-21 Foerfarande foer framstaellning av terapeutiskt verksamma fenyl-2-pyrrolidinoner samt deras isomerer

Country Status (26)

Country Link
JP (1) JPS5417734B1 (fi)
AT (2) AT304530B (fi)
AU (1) AU461836B2 (fi)
BE (1) BE770308A (fi)
BG (2) BG21025A3 (fi)
CA (1) CA954870A (fi)
CH (2) CH538474A (fi)
CS (2) CS174849B2 (fi)
DE (1) DE2136571C2 (fi)
DK (1) DK135584B (fi)
ES (1) ES393496A1 (fi)
FI (1) FI55184C (fi)
FR (1) FR2100946B1 (fi)
GB (1) GB1350582A (fi)
HU (1) HU162344B (fi)
IL (1) IL37147A (fi)
IN (1) IN132195B (fi)
IT (1) IT1046928B (fi)
MY (1) MY7500123A (fi)
NL (1) NL7109930A (fi)
PL (1) PL82184B1 (fi)
RO (2) RO61127A (fi)
SE (1) SE379347B (fi)
SU (2) SU479293A3 (fi)
YU (1) YU34671B (fi)
ZA (1) ZA714911B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2413935A1 (de) * 1974-03-20 1975-10-16 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone
NL7412694A (nl) * 1974-09-26 1976-03-30 Stamicarbon Werkwijze voor de bereiding van een pyrrolidon- -2.
DE2541855A1 (de) * 1975-09-18 1977-03-31 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone ii
AU518986B2 (en) * 1977-10-11 1981-10-29 Takeda Chemical Industries Ltd. Lactams
IL57266A (en) * 1978-06-12 1982-12-31 Mundipharma Ag Production of pyrrolidin-2-ones and of 3-pyrrolin-2-ones
US4548947A (en) * 1984-05-07 1985-10-22 Warner-Lambert Company 1-(Substituted-aryl)-dihydro-1H-pyrrolizine-3,5-[2H,6H-]diones and use for reversing amnesia
DE3823299A1 (de) * 1988-07-07 1990-01-11 Schering Ag Substituierte phenyl-pyrrolidin-2-one, -oxazolidin-2-one und -imidazolidin-2-one, ihre herstellung sowie verwendung in arzneimitteln
YU162789A (en) * 1988-09-01 1990-12-31 Lonza Ag 2-aza-4-(alcoxycarbonyl) spiro/4,5/decan-3-ones
JP2833817B2 (ja) * 1989-03-15 1998-12-09 三井化学株式会社 ４―エチル―３―（置換フェニル）―１―（３―トリフルオロメチルフェニル）―２―ピロリジノン誘導体、その製造法およびこれらを有効成分とする除草剤
PT100441A (pt) * 1991-05-02 1993-09-30 Smithkline Beecham Corp Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
AU2869092A (en) * 1991-10-11 1993-05-03 Smithkline Beecham Corporation Heterocyclic 3-phenylpyrrolidin-2-ones, their preparation and use for the manufacture of a medicament for inhibiting tumor necrosis factor production
US5665754A (en) * 1993-09-20 1997-09-09 Glaxo Wellcome Inc. Substituted pyrrolidines
US5747516A (en) * 1993-11-19 1998-05-05 E. I. Du Pont De Nemours And Company Dihydroazole compounds and their use for controlling fungal plant diseases
US6022870A (en) * 1998-01-14 2000-02-08 E. I. Du Pont De Nemours And Company Fungicidal cyclic amides
DE10205862A1 (de) * 2002-02-13 2003-08-21 Bayer Cropscience Ag DELTA1-Pyrroline

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR67024E (fr) * 1954-10-22 1957-11-04 Anciens Ets Barbier Appareil d'éclairage
US2984672A (en) * 1958-05-14 1961-05-16 Rohm & Haas Method for the preparation of pyrrolinones

Also Published As

Publication number Publication date
SE379347B (fi) 1975-10-06
AU461836B2 (en) 1975-06-05
ZA714911B (en) 1972-04-26
MY7500123A (en) 1975-12-31
JPS5417734B1 (fi) 1979-07-02
GB1350582A (en) 1974-04-18
BE770308A (fr) 1972-01-24
ES393496A1 (es) 1973-08-16
YU191271A (en) 1979-07-10
IL37147A (en) 1974-06-30
IN132195B (fi) 1975-08-02
DE2136571A1 (de) 1972-01-27
IT1046928B (it) 1980-07-31
BG21025A3 (bg) 1976-01-20
FR2100946A1 (fi) 1972-03-24
BG20582A3 (bg) 1975-12-05
RO61127A (fi) 1976-11-15
CH538474A (fr) 1973-06-30
FI55184C (fi) 1979-06-11
DK135584B (da) 1977-05-23
CS174849B2 (fi) 1977-04-29
SU488410A3 (ru) 1975-10-15
CH537921A (fr) 1973-07-31
CS174822B2 (fi) 1977-04-29
AT304530B (de) 1973-01-10
HU162344B (fi) 1973-01-29
AT310150B (de) 1973-09-25
NL7109930A (fi) 1972-01-26
CA954870A (en) 1974-09-17
AU3157571A (en) 1973-01-25
DE2136571C2 (de) 1982-03-25
FR2100946B1 (fi) 1975-06-06
SU479293A3 (ru) 1975-07-30
DK135584C (fi) 1977-10-31
PL82184B1 (fi) 1975-10-31
YU34671B (en) 1979-12-31
RO71354A (ro) 1982-02-26
IL37147A0 (en) 1971-08-25

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