FI49716B - - Google Patents

Info

Publication number
FI49716B
FI49716B FI2845/66A FI284566A FI49716B FI 49716 B FI49716 B FI 49716B FI 2845/66 A FI2845/66 A FI 2845/66A FI 284566 A FI284566 A FI 284566A FI 49716 B FI49716 B FI 49716B
Authority
FI
Finland
Application number
FI2845/66A
Other languages
Finnish (fi)
Other versions
FI49716C (fi
Inventor
Ronald Morton Cresswell
John William Mentha
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to FI281269A priority Critical patent/FI49155C/fi
Priority to FI101272A priority patent/FI55028C/fi
Publication of FI49716B publication Critical patent/FI49716B/fi
Application granted granted Critical
Publication of FI49716C publication Critical patent/FI49716C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
FI662845A 1965-10-28 1966-10-27 Menetelmä 2,4-diamino-5-bentsyyli-pyrimidiinien valmistamiseksi. FI49716C (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI281269A FI49155C (fi) 1965-10-28 1969-09-30 Uudet yhdisteet, joita käytetään välituotteina bakteerienvastaisten yh disteiden, 2,4-diamino-5-bentsyylipyrimidiinien valmistamiseksi, ja me netelmä niiden valmistamiseksi.
FI101272A FI55028C (fi) 1965-10-28 1972-04-11 Foerfarande foer framstaellning av alfa-bensyl-beta beta-dialkoxipropionitriler

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB45657/65A GB1142654A (en) 1965-10-28 1965-10-28 Cyano-acetals and their use in benzylpyrimidine synthesis

Publications (2)

Publication Number Publication Date
FI49716B true FI49716B (xx) 1975-06-02
FI49716C FI49716C (fi) 1975-09-10

Family

ID=10438067

Family Applications (1)

Application Number Title Priority Date Filing Date
FI662845A FI49716C (fi) 1965-10-28 1966-10-27 Menetelmä 2,4-diamino-5-bentsyyli-pyrimidiinien valmistamiseksi.

Country Status (16)

Country Link
US (2) US3513185A (xx)
JP (1) JPS50657B1 (xx)
AT (1) AT271479B (xx)
BE (1) BE689071A (xx)
BR (1) BR6684142D0 (xx)
CH (1) CH484875A (xx)
DE (2) DE1593723C3 (xx)
DK (3) DK120546B (xx)
ES (1) ES332806A1 (xx)
FI (1) FI49716C (xx)
GB (1) GB1142654A (xx)
IL (1) IL26755A (xx)
NL (1) NL150442B (xx)
NO (1) NO127616B (xx)
PL (1) PL69908B1 (xx)
SE (3) SE349580B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2065367C2 (de) * 1969-03-06 1985-04-04 The Wellcome Foundation Ltd., London Verfahren zur Herstellung von 2,4- Diamino-5-benzylpyrimidinen
GB1261455A (en) * 1969-03-06 1972-01-26 Burroughs Wellcome Co Improvements in or relating to substituted acrylonitriles
BE789904A (fr) * 1971-10-12 1973-04-10 Wellcome Found Procedes de synthese organique
USRE29467E (en) * 1971-12-20 1977-11-08 Plantex, Ltd. Benzylcyano-amides
US3910984A (en) * 1972-11-27 1975-10-07 Plantex Ltd Benzylcyano-amides
AR207561A1 (es) * 1973-03-17 1976-10-15 Heumann Ludwig & Co Gmbh Procedimiento para la sintesis de 2,4-diamino 5(3'-metoxi-5'-substituido o no-4'alquildioxial-quilen-bencil)pirimidina
DK397574A (xx) * 1973-08-24 1975-04-28 Ciba Geigy Ag
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
DE2623170C2 (de) * 1976-05-22 1982-03-11 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von α-Cyanzimtaldehyd-Derivaten und 3,4,5-Trimethoxy-α-Cyanzimtaldehyd
GB1582245A (en) * 1976-06-09 1981-01-07 Wellcome Found Benzyl cyanoacetal derivatives and their conversion to pyrimidine derivatives
US4659861A (en) * 1981-11-03 1987-04-21 The Dow Chemical Company Novel nitrile functional glycol ether acetals
DE3211679A1 (de) * 1982-03-30 1983-10-06 Dynamit Nobel Ag Verfahren zur herstellung von acetalen und enolaethern aus acyloxymethylenverbindungen
JPS59120U (ja) * 1982-06-22 1984-01-05 株式会社タカハベッド 歩行練習器を兼ねた身障者用椅子
FR2602507B1 (fr) * 1986-08-08 1989-06-09 Sanofi Pharma Procede de preparation de diamino-2,4 benzyl-5 pyrimidines
JPH07509215A (ja) * 1990-11-14 1995-10-12 カイロン　コーポレイション ジヒドロ葉酸還元酵素の特異的阻害およびそのための化合物
CN103570631B (zh) * 2013-11-21 2016-05-25 华中农业大学 氚标记二甲氧苄啶的制备方法
CN103601688A (zh) * 2013-11-25 2014-02-26 四川大学 一种甲氧苄啶杂质的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2755298A (en) * 1956-07-17 pwiiq
US3049544A (en) * 1962-08-14 Method for the preparation of
US2745866A (en) * 1953-01-22 1956-05-15 Searle & Co Alpha, beta-diaryl substitution products of alpha-alkenonitriles
US2951089A (en) * 1953-12-28 1960-08-30 Schering Corp Alkyl ethers of polyiodophenyl propionic acids
US3128300A (en) * 1960-12-09 1964-04-07 Monsanto Chemicals 3-phenoxyacrylonitriles prepared by cyanovinylation reaction
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes

Also Published As

Publication number Publication date
DE1793767C3 (de) 1980-07-10
DE1593723C3 (de) 1978-04-27
CH484875A (de) 1970-01-31
NO127616B (xx) 1973-07-23
DE1793767A1 (de) 1973-11-08
SE344746B (xx) 1972-05-02
ES332806A1 (es) 1967-10-01
DK127415B (da) 1973-11-05
DE1593723B2 (de) 1977-06-16
US3671564A (en) 1972-06-20
US3513185A (en) 1970-05-19
BE689071A (xx) 1967-04-28
DK125849B (da) 1973-05-14
SE390634B (sv) 1977-01-03
JPS50657B1 (xx) 1975-01-10
PL69908B1 (xx) 1973-10-31
DE1793767B2 (de) 1979-10-31
DE1593723A1 (de) 1972-04-13
NL6615287A (xx) 1967-05-02
IL26755A (en) 1970-10-30
SE349580B (xx) 1972-10-02
AT271479B (de) 1969-06-10
FI49716C (fi) 1975-09-10
GB1142654A (en) 1969-02-12
BR6684142D0 (pt) 1973-12-26
DK120546B (da) 1971-06-14
NL150442B (nl) 1976-08-16

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