FI20140266A7 - Menetelmä ja laite nanopartikkeleiden valmistamiseksi - Google Patents

Menetelmä ja laite nanopartikkeleiden valmistamiseksi Download PDF

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Publication number
FI20140266A7
FI20140266A7 FI20140266A FI20140266A FI20140266A7 FI 20140266 A7 FI20140266 A7 FI 20140266A7 FI 20140266 A FI20140266 A FI 20140266A FI 20140266 A FI20140266 A FI 20140266A FI 20140266 A7 FI20140266 A7 FI 20140266A7
Authority
FI
Finland
Prior art keywords
producing nanoparticles
nanoparticles
producing
controlled
relates
Prior art date
Application number
FI20140266A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Inventor
Jouko Yliruusi
Heikki Räikkönen
Edward Haeggström
Kai Falk
Jenni Pessi
Ilkka Lassila
Antti Meriläinen
Original Assignee
Nanoform Finland Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanoform Finland Oy filed Critical Nanoform Finland Oy
Priority to FI20140266A priority Critical patent/FI20140266A7/fi
Priority to US15/512,070 priority patent/US10098842B2/en
Priority to PT157938572T priority patent/PT3204150T/pt
Priority to ES15793857T priority patent/ES2969055T3/es
Priority to FIEP15793857.2T priority patent/FI3204150T3/fi
Priority to CA2961107A priority patent/CA2961107C/en
Priority to JP2017537021A priority patent/JP6599995B2/ja
Priority to DK15793857.2T priority patent/DK3204150T3/da
Priority to EP15793857.2A priority patent/EP3204150B1/en
Priority to PL15793857.2T priority patent/PL3204150T3/pl
Priority to PCT/FI2015/050664 priority patent/WO2016055696A1/en
Publication of FI20140266A7 publication Critical patent/FI20140266A7/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/02—Crystallisation from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
    • B01J3/008—Processes carried out under supercritical conditions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Nanotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Optics & Photonics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Steroid Compounds (AREA)
FI20140266A 2014-10-06 2014-10-06 Menetelmä ja laite nanopartikkeleiden valmistamiseksi FI20140266A7 (fi)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FI20140266A FI20140266A7 (fi) 2014-10-06 2014-10-06 Menetelmä ja laite nanopartikkeleiden valmistamiseksi
US15/512,070 US10098842B2 (en) 2014-10-06 2015-10-05 Method and a device for producing nanoparticles
PT157938572T PT3204150T (pt) 2014-10-06 2015-10-05 Método para produzir nanopartículas
ES15793857T ES2969055T3 (es) 2014-10-06 2015-10-05 Un método para la producción de nanopartículas
FIEP15793857.2T FI3204150T3 (fi) 2014-10-06 2015-10-05 Menetelmä nanopartikkeleiden tuottamiseksi
CA2961107A CA2961107C (en) 2014-10-06 2015-10-05 A method and a device for producing nanoparticles
JP2017537021A JP6599995B2 (ja) 2014-10-06 2015-10-05 ナノ粒子を製造するための方法及び装置
DK15793857.2T DK3204150T3 (da) 2014-10-06 2015-10-05 Fremgangsmåde til at producere nanopartikler
EP15793857.2A EP3204150B1 (en) 2014-10-06 2015-10-05 A method for producing nanoparticles
PL15793857.2T PL3204150T3 (pl) 2014-10-06 2015-10-05 Sposób wytwarzania nanocząstek
PCT/FI2015/050664 WO2016055696A1 (en) 2014-10-06 2015-10-05 A method and a device for producing nanoparticles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20140266A FI20140266A7 (fi) 2014-10-06 2014-10-06 Menetelmä ja laite nanopartikkeleiden valmistamiseksi

Publications (1)

Publication Number Publication Date
FI20140266A7 true FI20140266A7 (fi) 2016-04-07

Family

ID=54540113

Family Applications (2)

Application Number Title Priority Date Filing Date
FI20140266A FI20140266A7 (fi) 2014-10-06 2014-10-06 Menetelmä ja laite nanopartikkeleiden valmistamiseksi
FIEP15793857.2T FI3204150T3 (fi) 2014-10-06 2015-10-05 Menetelmä nanopartikkeleiden tuottamiseksi

Family Applications After (1)

Application Number Title Priority Date Filing Date
FIEP15793857.2T FI3204150T3 (fi) 2014-10-06 2015-10-05 Menetelmä nanopartikkeleiden tuottamiseksi

Country Status (10)

Country Link
US (1) US10098842B2 (enExample)
EP (1) EP3204150B1 (enExample)
JP (1) JP6599995B2 (enExample)
CA (1) CA2961107C (enExample)
DK (1) DK3204150T3 (enExample)
ES (1) ES2969055T3 (enExample)
FI (2) FI20140266A7 (enExample)
PL (1) PL3204150T3 (enExample)
PT (1) PT3204150T (enExample)
WO (1) WO2016055696A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105641968B (zh) * 2016-01-07 2018-04-17 中国原子能科学研究院 一种具有在线光谱监测功能的超临界流体络合反应装置
FI127408B (en) 2016-09-29 2018-05-15 Nanoform Finland Oy Device, method and equipment for solubility testing
US11298668B2 (en) 2017-11-09 2022-04-12 Blh Ecology Concepts, Llc Process to produce nanoparticles
CN111012671B (zh) * 2019-11-25 2022-07-05 上海强德食品科技有限公司 一种微胶囊的物理制备方法
CN111215002B (zh) * 2020-01-20 2021-08-10 中南大学 高温高压超临界二氧化碳反应釜
FI129026B (en) 2020-01-29 2021-05-31 Nanoform Finland Oy System and method for producing particles of organic substances
EP3884930A1 (en) 2020-03-23 2021-09-29 Bayer AG Nano-dry-melting
CN111721495B (zh) * 2020-06-16 2022-02-08 中国人民解放军国防科技大学 一种新型纳米粒子平面激光散射实验的粒子生成装置
WO2024153733A1 (en) 2023-01-18 2024-07-25 Helm Ag Crystalline nanoparticles comprising enzalutamide
US12303845B2 (en) 2023-01-18 2025-05-20 Nanoform Finland Oyj Method for crystallization of active pharmaceutical ingredients
WO2025125509A1 (en) 2023-12-12 2025-06-19 Targtex S.A. Chemotherapeutic agent and compositions
WO2025153768A1 (en) 2024-01-18 2025-07-24 Nanoform Finland Oyj Composition comprising crystalline nanosized apalutamide

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102124B2 (ja) * 1985-12-27 1994-12-14 日本分光工業株式会社 超臨界流体による試料の分離回収方法
JP2774349B2 (ja) * 1990-03-17 1998-07-09 株式会社神戸製鋼所 微粒の製造方法
WO1997014407A1 (en) 1995-10-17 1997-04-24 Research Triangle Pharmaceuticals Insoluble drug delivery
JP3986086B2 (ja) 1996-03-01 2007-10-03 ザ ユニバーシティ オブ カンザス 近臨界および超臨界反溶媒を用いる粒子析出方法および被覆方法
CA2294367A1 (en) * 1997-06-20 1998-12-30 Smithkline Beecham P.L.C. Treatment of a substance with a dense fluid (e.g. with a supercritical fluid)
US6177103B1 (en) 1998-06-19 2001-01-23 Rtp Pharma, Inc. Processes to generate submicron particles of water-insoluble compounds
FR2802445B1 (fr) * 1999-12-15 2002-02-15 Separex Sa Procede et dispositif de captage de fines particules par piegeage au sein d'un melange solide de type neige carbonique
US7279181B2 (en) 2003-06-03 2007-10-09 Ferro Corporation Method for preparation of particles from solution-in-supercritical fluid or compressed gas emulsions
US7754243B2 (en) 2004-08-03 2010-07-13 Clemson University Research Foundation Aqueous suspension of nanoscale drug particles from supercritical fluid processing
GB0525852D0 (en) * 2005-12-20 2006-02-01 Accentus Plc Crystallisation apparatus and process
JP2007301534A (ja) 2006-05-15 2007-11-22 Ebara Corp 微細化装置
US8585943B2 (en) * 2007-12-07 2013-11-19 Xspray Microparticles Ab Method and arrangement for the production of particles
JP5933234B2 (ja) * 2011-11-24 2016-06-08 国立大学法人東北大学 微粒子作製装置

Also Published As

Publication number Publication date
CA2961107A1 (en) 2016-04-14
EP3204150B1 (en) 2023-11-29
FI3204150T3 (fi) 2023-12-04
PL3204150T3 (pl) 2024-05-13
US10098842B2 (en) 2018-10-16
PT3204150T (pt) 2024-03-04
CA2961107C (en) 2023-01-03
US20170231914A1 (en) 2017-08-17
JP6599995B2 (ja) 2019-10-30
EP3204150A1 (en) 2017-08-16
ES2969055T3 (es) 2024-05-16
JP2017536983A (ja) 2017-12-14
WO2016055696A1 (en) 2016-04-14
DK3204150T3 (da) 2024-03-04

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Owner name: NANOFORM FINLAND OY

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