FI20012143A - Itiötön Bacillus subtilis, sen valmistus ja käyttö - Google Patents

Itiötön Bacillus subtilis, sen valmistus ja käyttö Download PDF

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Publication number
FI20012143A
FI20012143A FI20012143A FI20012143A FI20012143A FI 20012143 A FI20012143 A FI 20012143A FI 20012143 A FI20012143 A FI 20012143A FI 20012143 A FI20012143 A FI 20012143A FI 20012143 A FI20012143 A FI 20012143A
Authority
FI
Finland
Prior art keywords
spore
preparation
bacillus subtilis
forming bacillus
forming
Prior art date
Application number
FI20012143A
Other languages
English (en)
Swedish (sv)
Other versions
FI20012143A0 (fi
FI112666B (fi
Inventor
Pertti Koski
Susanna Kaeaeriaeinen
Original Assignee
Ipsat Therapies Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsat Therapies Oy filed Critical Ipsat Therapies Oy
Publication of FI20012143A0 publication Critical patent/FI20012143A0/fi
Priority to FI20012143A priority Critical patent/FI112666B/fi
Priority to EP02774801.1A priority patent/EP1451292B1/en
Priority to JP2003542599A priority patent/JP5486142B2/ja
Priority to PL370064A priority patent/PL205348B1/pl
Priority to US10/494,411 priority patent/US7319030B2/en
Priority to HU0402070A priority patent/HUP0402070A3/hu
Priority to CA2465828A priority patent/CA2465828C/en
Priority to NZ532865A priority patent/NZ532865A/en
Priority to ES02774801.1T priority patent/ES2452292T3/es
Priority to AU2002340536A priority patent/AU2002340536C1/en
Priority to PCT/FI2002/000861 priority patent/WO2003040352A1/en
Publication of FI20012143A publication Critical patent/FI20012143A/fi
Application granted granted Critical
Publication of FI112666B publication Critical patent/FI112666B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus
    • C12R2001/125Bacillus subtilis ; Hay bacillus; Grass bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
FI20012143A 2001-11-06 2001-11-06 Itiöimätön Bacillus subtilis, sen valmistus ja käyttö FI112666B (fi)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FI20012143A FI112666B (fi) 2001-11-06 2001-11-06 Itiöimätön Bacillus subtilis, sen valmistus ja käyttö
CA2465828A CA2465828C (en) 2001-11-06 2002-11-05 Non-sporulating bacillus subtilis having parts of the gene encoding sigma g deleted
JP2003542599A JP5486142B2 (ja) 2001-11-06 2002-11-05 シグマgをコードする遺伝子の部分が欠失している非胞子形成枯草菌
PL370064A PL205348B1 (pl) 2001-11-06 2002-11-05 Nieprzetrwalnikujący szczep Bacillus subtilis, sposób wytwarzania nieprzetrwalnikującego szczepu Bacillus subtilis, zastosowanie nieprzetrwalnikującego szczepu Bacillus subtilis i sposób wytwarzania biologicznie przygotowanego preparatu
US10/494,411 US7319030B2 (en) 2001-11-06 2002-11-05 Non-sporulating Bacillus subtilis having parts of the gene encoding sigma G deleted
HU0402070A HUP0402070A3 (en) 2001-11-06 2002-11-05 Non-sporulating bacillus subtilis having parts of the gene encoding sigma g deleted
EP02774801.1A EP1451292B1 (en) 2001-11-06 2002-11-05 Non-sporulating bacillus subtilis having parts of the gene encoding sigma g deleted
NZ532865A NZ532865A (en) 2001-11-06 2002-11-05 Non-sporulating bacillus subtilis having parts of the gene encoding sigma G deleted
ES02774801.1T ES2452292T3 (es) 2001-11-06 2002-11-05 Bacillus subtilis no esporulante que tiene partes del gen que codifica Sigma G eliminadas
AU2002340536A AU2002340536C1 (en) 2001-11-06 2002-11-05 Non-sporulating bacillus subtilis having parts of the gene encoding sigma G deleted
PCT/FI2002/000861 WO2003040352A1 (en) 2001-11-06 2002-11-05 Non-sporulating bacillus subtilis having parts of the gene encoding sigma g deleted

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20012143A FI112666B (fi) 2001-11-06 2001-11-06 Itiöimätön Bacillus subtilis, sen valmistus ja käyttö
FI20012143 2001-11-06

Publications (3)

Publication Number Publication Date
FI20012143A0 FI20012143A0 (fi) 2001-11-06
FI20012143A true FI20012143A (fi) 2003-05-07
FI112666B FI112666B (fi) 2003-12-31

Family

ID=8562192

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20012143A FI112666B (fi) 2001-11-06 2001-11-06 Itiöimätön Bacillus subtilis, sen valmistus ja käyttö

Country Status (11)

Country Link
US (1) US7319030B2 (fi)
EP (1) EP1451292B1 (fi)
JP (1) JP5486142B2 (fi)
AU (1) AU2002340536C1 (fi)
CA (1) CA2465828C (fi)
ES (1) ES2452292T3 (fi)
FI (1) FI112666B (fi)
HU (1) HUP0402070A3 (fi)
NZ (1) NZ532865A (fi)
PL (1) PL205348B1 (fi)
WO (1) WO2003040352A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004113510A2 (en) * 2003-06-18 2004-12-29 Dsm Ip Assets B.V. Production of pantothenate using microorganisms incapable of sporulation
DE10344200A1 (de) * 2003-09-22 2005-05-04 Basf Ag Verfahren zur Herstellung eines D-Pantothensäure und/oder deren Salze enthaltendes Tierfuttersupplement
FI119190B (fi) * 2006-06-21 2008-08-29 Ipsat Therapies Oy Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi
FI20105572A0 (fi) 2010-05-24 2010-05-24 Prevab R Lcc Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt
BR112016023360B1 (pt) 2014-04-17 2023-03-07 Synthetic Biologics, Inc Beta-lactamase e seu uso
AU2015308897B2 (en) 2014-08-28 2021-03-04 Theriva Biologics, Inc. E. coli-based production of beta-lactamase
AU2015330937B2 (en) 2014-10-08 2021-07-15 Theriva Biologics, Inc. Beta-lactamase formulations and uses thereof
WO2016105498A1 (en) 2014-12-23 2016-06-30 Synthetic Biologics, Inc. Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics
AU2016222936B2 (en) 2015-02-23 2022-01-06 Theriva Biologics, Inc. Carbapenemases for use with antibiotics for the protection of the intestinal microbiome
WO2016144856A1 (en) 2015-03-06 2016-09-15 Synthetic Biologics, Inc. Safe and effective beta-lactamase dosing for microbiome protection
CN105200076A (zh) * 2015-09-23 2015-12-30 江南大学 一株重组表达γ-内酰胺酶的枯草芽孢杆菌、固定化及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2003078A1 (en) * 1988-11-18 1990-05-18 Alan Sloma Protease deletion
JPH11509096A (ja) 1995-07-07 1999-08-17 ノボ ノルディスク アクティーゼルスカブ 胞子形成できないバチルスを用いるタンパク質の生産
DK1391502T3 (da) * 2001-05-29 2012-05-21 Kao Corp Værtsmikroorganismer

Also Published As

Publication number Publication date
EP1451292B1 (en) 2014-01-29
PL205348B1 (pl) 2010-04-30
WO2003040352A9 (en) 2003-08-14
WO2003040352A1 (en) 2003-05-15
JP5486142B2 (ja) 2014-05-07
EP1451292A1 (en) 2004-09-01
US7319030B2 (en) 2008-01-15
AU2002340536C1 (en) 2008-05-08
HUP0402070A2 (hu) 2005-01-28
AU2002340536B2 (en) 2007-05-24
NZ532865A (en) 2005-09-30
CA2465828C (en) 2014-05-13
PL370064A1 (en) 2005-05-16
FI20012143A0 (fi) 2001-11-06
JP2005508184A (ja) 2005-03-31
US20050158843A1 (en) 2005-07-21
HUP0402070A3 (en) 2010-01-28
FI112666B (fi) 2003-12-31
CA2465828A1 (en) 2003-05-15
ES2452292T3 (es) 2014-03-31

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