FI20002525A - Tulehduksenvastaisia aineita - Google Patents

Tulehduksenvastaisia aineita

Info

Publication number
FI20002525A
FI20002525A FI20002525A FI20002525A FI20002525A FI 20002525 A FI20002525 A FI 20002525A FI 20002525 A FI20002525 A FI 20002525A FI 20002525 A FI20002525 A FI 20002525A FI 20002525 A FI20002525 A FI 20002525A
Authority
FI
Finland
Prior art keywords
inflammatory substances
inflammation
prevention
treatment
general formula
Prior art date
Application number
FI20002525A
Other languages
English (en)
Swedish (sv)
Other versions
FI20002525A0 (fi
Inventor
Heimo Haikala
Minja Hyttilae-Hopponen
Erkki Nissinen
Minna Ruotsalainen
Aino Pippuri
Kari Loennberg
Original Assignee
Orion Yhtymae Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oyj filed Critical Orion Yhtymae Oyj
Priority to FI20002525A priority Critical patent/FI20002525A/fi
Publication of FI20002525A0 publication Critical patent/FI20002525A0/fi
Priority to DK01996384T priority patent/DK1341539T3/da
Priority to EP01996384A priority patent/EP1341539B1/en
Priority to PCT/FI2001/001000 priority patent/WO2002040025A1/en
Priority to CA2429109A priority patent/CA2429109C/en
Priority to ES01996384T priority patent/ES2240564T3/es
Priority to PT01996384T priority patent/PT1341539E/pt
Priority to JP2002542398A priority patent/JP4309652B2/ja
Priority to SI200130371T priority patent/SI1341539T1/xx
Priority to US10/416,713 priority patent/US6878702B2/en
Priority to AU2002223708A priority patent/AU2002223708A1/en
Priority to AT01996384T priority patent/ATE294581T1/de
Priority to DE60110628T priority patent/DE60110628T2/de
Publication of FI20002525A publication Critical patent/FI20002525A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI20002525A 2000-11-17 2000-11-17 Tulehduksenvastaisia aineita FI20002525A (fi)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FI20002525A FI20002525A (fi) 2000-11-17 2000-11-17 Tulehduksenvastaisia aineita
DE60110628T DE60110628T2 (de) 2000-11-17 2001-11-16 Antiphlogistische mittel
PT01996384T PT1341539E (pt) 2000-11-17 2001-11-16 Agentes anti-inflamatorios
EP01996384A EP1341539B1 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
PCT/FI2001/001000 WO2002040025A1 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
CA2429109A CA2429109C (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
ES01996384T ES2240564T3 (es) 2000-11-17 2001-11-16 Agentes antinflamatorios.
DK01996384T DK1341539T3 (da) 2000-11-17 2001-11-16 Antiinflammatoriske midler
JP2002542398A JP4309652B2 (ja) 2000-11-17 2001-11-16 抗炎症剤
SI200130371T SI1341539T1 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
US10/416,713 US6878702B2 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
AU2002223708A AU2002223708A1 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
AT01996384T ATE294581T1 (de) 2000-11-17 2001-11-16 Antiphlogistische mittel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20002525A FI20002525A (fi) 2000-11-17 2000-11-17 Tulehduksenvastaisia aineita

Publications (2)

Publication Number Publication Date
FI20002525A0 FI20002525A0 (fi) 2000-11-17
FI20002525A true FI20002525A (fi) 2002-05-18

Family

ID=8559519

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20002525A FI20002525A (fi) 2000-11-17 2000-11-17 Tulehduksenvastaisia aineita

Country Status (11)

Country Link
US (1) US6878702B2 (fi)
EP (1) EP1341539B1 (fi)
JP (1) JP4309652B2 (fi)
AT (1) ATE294581T1 (fi)
AU (1) AU2002223708A1 (fi)
CA (1) CA2429109C (fi)
DE (1) DE60110628T2 (fi)
ES (1) ES2240564T3 (fi)
FI (1) FI20002525A (fi)
PT (1) PT1341539E (fi)
WO (1) WO2002040025A1 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1612204A4 (en) * 2003-03-31 2007-04-11 Daiichi Seiyaku Co HYDRAZONE DERIVATIVE
DE10337904A1 (de) * 2003-08-18 2005-03-24 Universität Duisburg-Essen Substanzen für die Apoptoseregulation, insbesondere Apoptosestimulation
BRPI0816767B8 (pt) 2007-09-14 2021-05-25 Addex Pharmaceuticals Sa composto 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridi¬nil-2'-onas 1',3'-dissubstituídas, composição farmacêutica e uso dos mesmos
CA3161960A1 (en) 2019-12-16 2021-06-24 Tenax Therapeutics, Inc. Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (ph-hfpef)
CN112500353B (zh) * 2020-12-08 2022-11-25 北京晨光同创医药研究院有限公司 一种左西孟旦的前药化合物、制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
US5185332A (en) * 1989-02-11 1993-02-09 Orion-Yhtyma Oy Thiadiazines and pharmaceutical compositions thereof as well as method of use
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
US6183948B1 (en) * 1998-04-15 2001-02-06 Johns Hopkins University Methods to identify compounds affecting mitochondria

Also Published As

Publication number Publication date
DE60110628D1 (de) 2005-06-09
CA2429109A1 (en) 2002-05-23
EP1341539A1 (en) 2003-09-10
ES2240564T3 (es) 2005-10-16
ATE294581T1 (de) 2005-05-15
DE60110628T2 (de) 2006-01-19
WO2002040025A1 (en) 2002-05-23
AU2002223708A1 (en) 2002-05-27
US6878702B2 (en) 2005-04-12
JP4309652B2 (ja) 2009-08-05
EP1341539B1 (en) 2005-05-04
FI20002525A0 (fi) 2000-11-17
JP2004520278A (ja) 2004-07-08
PT1341539E (pt) 2005-07-29
CA2429109C (en) 2010-02-16
US20040029870A1 (en) 2004-02-12

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