ATE375334T1 - Harnstoff derivate als entzündungshemmende mittel - Google Patents

Harnstoff derivate als entzündungshemmende mittel

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Publication number
ATE375334T1
ATE375334T1 AT00978751T AT00978751T ATE375334T1 AT E375334 T1 ATE375334 T1 AT E375334T1 AT 00978751 T AT00978751 T AT 00978751T AT 00978751 T AT00978751 T AT 00978751T AT E375334 T1 ATE375334 T1 AT E375334T1
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AT
Austria
Prior art keywords
inflammatory agents
urea derivatives
compounds
disclosed
useful
Prior art date
Application number
AT00978751T
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English (en)
Inventor
Steffen Breitfelder
Pier Cirillo
Ming-Hong Hao
Eugene Hickey
Rajiv Sharma
Sanxing Sun
Hidenori Takahashi
Original Assignee
Boehringer Ingelheim Pharma
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Publication of ATE375334T1 publication Critical patent/ATE375334T1/de

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
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    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
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    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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AT00978751T 1999-11-16 2000-11-16 Harnstoff derivate als entzündungshemmende mittel ATE375334T1 (de)

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CA2389360A1 (en) 2001-05-25
DE60036726D1 (de) 2007-11-22
EP1232150B1 (de) 2007-10-10
US20030125354A1 (en) 2003-07-03
EP1232150A1 (de) 2002-08-21
ES2292488T3 (es) 2008-03-16
DE60036726T2 (de) 2008-02-07
JP4955171B2 (ja) 2012-06-20
CA2389360C (en) 2008-06-03
US6492393B1 (en) 2002-12-10
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