FI127024B - Multivalentteja yhdisteitä käytettäväksi aivovaurion hoidossa ja estämisessä - Google Patents

Multivalentteja yhdisteitä käytettäväksi aivovaurion hoidossa ja estämisessä Download PDF

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Publication number
FI127024B
FI127024B FI20145861A FI20145861A FI127024B FI 127024 B FI127024 B FI 127024B FI 20145861 A FI20145861 A FI 20145861A FI 20145861 A FI20145861 A FI 20145861A FI 127024 B FI127024 B FI 127024B
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FI
Finland
Prior art keywords
tai
suola
joukosta
yes
yhdiste
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Application number
FI20145861A
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English (en)
Icelandic (is)
Swedish (sv)
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FI20145861A (fi
Inventor
Adrian Harel
Original Assignee
Adrian Harel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adrian Harel filed Critical Adrian Harel
Priority to FI20145861A priority Critical patent/FI127024B/fi
Priority to US15/516,192 priority patent/US9975846B2/en
Priority to EP15784732.8A priority patent/EP3201173B1/en
Priority to ES15784732T priority patent/ES2830386T3/es
Priority to DK15784732.8T priority patent/DK3201173T3/da
Priority to PCT/FI2015/050659 priority patent/WO2016051024A1/en
Publication of FI20145861A publication Critical patent/FI20145861A/fi
Priority to IL25140717A priority patent/IL251407B/en
Application granted granted Critical
Publication of FI127024B publication Critical patent/FI127024B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/64—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/27—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/44—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI20145861A 2014-10-03 2014-10-03 Multivalentteja yhdisteitä käytettäväksi aivovaurion hoidossa ja estämisessä FI127024B (fi)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FI20145861A FI127024B (fi) 2014-10-03 2014-10-03 Multivalentteja yhdisteitä käytettäväksi aivovaurion hoidossa ja estämisessä
US15/516,192 US9975846B2 (en) 2014-10-03 2015-10-02 Multivalent compounds for use in the treatment and prevention of brain damage
EP15784732.8A EP3201173B1 (en) 2014-10-03 2015-10-02 Multivalent compounds for use in the treatment and prevention of brain damage
ES15784732T ES2830386T3 (es) 2014-10-03 2015-10-02 Compuestos multivalentes para el uso en el tratamiento y la prevención del daño cerebral
DK15784732.8T DK3201173T3 (da) 2014-10-03 2015-10-02 Multivalente forbindelser til anvendelse i behandlingen og forebyggelsen af hjerneskade
PCT/FI2015/050659 WO2016051024A1 (en) 2014-10-03 2015-10-02 Multivalent compounds for use in the treatment and prevention of brain damage
IL25140717A IL251407B (en) 2014-10-03 2017-03-27 A multivalent compound for the treatment and prevention of brain damage

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20145861A FI127024B (fi) 2014-10-03 2014-10-03 Multivalentteja yhdisteitä käytettäväksi aivovaurion hoidossa ja estämisessä

Publications (2)

Publication Number Publication Date
FI20145861A FI20145861A (fi) 2016-04-04
FI127024B true FI127024B (fi) 2017-09-29

Family

ID=54347566

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20145861A FI127024B (fi) 2014-10-03 2014-10-03 Multivalentteja yhdisteitä käytettäväksi aivovaurion hoidossa ja estämisessä

Country Status (7)

Country Link
US (1) US9975846B2 (fi)
EP (1) EP3201173B1 (fi)
DK (1) DK3201173T3 (fi)
ES (1) ES2830386T3 (fi)
FI (1) FI127024B (fi)
IL (1) IL251407B (fi)
WO (1) WO2016051024A1 (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI130262B (fi) 2019-08-30 2023-05-17 Medicortex Finland Oy Koostumuksia ja koostumuksia käytettäväksi aivovaurion ja neurodegeneratiivisten sairauksien ennaltaehkäisemisessä tai hoitamisessa
FR3123129B1 (fr) 2021-05-22 2023-11-10 Dreamtronic Cadre a eclairage infrarouge d’ecran tactile, dote de diodes uvc

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH501037A (de) * 1968-01-10 1970-12-31 Ciba Geigy Ag Verfahren zur Herstellung neuer wasserunlöslicher Azoverbindungen
JP4342952B2 (ja) 2002-04-03 2009-10-14 プレバ、バイオテック、ソシエダッド、アノニマ 神経変性疾患の防御のための天然フェノール系産物およびその誘導体
US8227643B2 (en) 2002-05-31 2012-07-24 Proteotech, Inc. Sirtuin 1 and the treatment of neurodegenerative diseases
US9422308B2 (en) 2012-04-16 2016-08-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Derivatives of docosahexaenoylethanolamide and uses thereof

Also Published As

Publication number Publication date
IL251407A0 (en) 2017-05-29
EP3201173B1 (en) 2020-10-14
WO2016051024A1 (en) 2016-04-07
EP3201173A1 (en) 2017-08-09
IL251407B (en) 2019-10-31
FI20145861A (fi) 2016-04-04
DK3201173T3 (da) 2020-11-16
US9975846B2 (en) 2018-05-22
ES2830386T3 (es) 2021-06-03
US20170298010A1 (en) 2017-10-19

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