FI126711B - Bedömning av en hälsorisk i samband med serotoninbrist - Google Patents

Bedömning av en hälsorisk i samband med serotoninbrist Download PDF

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Publication number
FI126711B
FI126711B FI20116007A FI20116007A FI126711B FI 126711 B FI126711 B FI 126711B FI 20116007 A FI20116007 A FI 20116007A FI 20116007 A FI20116007 A FI 20116007A FI 126711 B FI126711 B FI 126711B
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FI
Finland
Prior art keywords
bifidobacteria
serotonin
clostridia
health risk
relative proportion
Prior art date
Application number
FI20116007A
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English (en)
Finnish (fi)
Other versions
FI20116007A (sv
FI20116007A0 (sv
Inventor
Annika Mäyrä-Mäkinen
Eveliina Munukka
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Gut Guide Oy
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Application filed by Gut Guide Oy filed Critical Gut Guide Oy
Priority to FI20116007A priority Critical patent/FI126711B/sv
Publication of FI20116007A0 publication Critical patent/FI20116007A0/sv
Priority to US14/350,941 priority patent/US10087480B2/en
Priority to EP12840489.4A priority patent/EP2766027B1/en
Priority to PCT/FI2012/050978 priority patent/WO2013054001A1/en
Publication of FI20116007A publication Critical patent/FI20116007A/sv
Application granted granted Critical
Publication of FI126711B publication Critical patent/FI126711B/sv

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1234Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • G01N2800/301Anxiety or phobic disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • G01N2800/303Eating disorders, e.g. anorexia, bulimia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • G01N2800/304Mood disorders, e.g. bipolar, depression
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Polymers & Plastics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Physics & Mathematics (AREA)

Claims (2)

1. Menetelmä serotoniinivajeeseen liittyvän terveysriskin arvioimiseksi, tunnettu siitä, että menetelmässä määritetään in vitro bifidobaktee-rien osuus suoliston Erec-ryhmän klostrideihin nähden, jolloin bifidobakteerien mainittu osuus korreloi negatiivisesti terveysriskin kanssa. Patentkrav
1. Förfarande för bedömning av en hälsorisk i samband med sero-toninbrist, kännetecknat av att i förfarandet fastställs i n vitro andelen bi-fidobakterier i förhållande till klostridier i Erec-gruppen i mag-tarmkanalen, varvid bifidobakteriernas nämnda andel korrelerar negativt med hälsorisken.
FI20116007A 2011-10-12 2011-10-12 Bedömning av en hälsorisk i samband med serotoninbrist FI126711B (sv)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FI20116007A FI126711B (sv) 2011-10-12 2011-10-12 Bedömning av en hälsorisk i samband med serotoninbrist
US14/350,941 US10087480B2 (en) 2011-10-12 2012-10-12 Raising and diagnosing of serotonin level
EP12840489.4A EP2766027B1 (en) 2011-10-12 2012-10-12 Raising and diagnosing of serotonin level
PCT/FI2012/050978 WO2013054001A1 (en) 2011-10-12 2012-10-12 Raising and diagnosing of serotonin level

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20116007A FI126711B (sv) 2011-10-12 2011-10-12 Bedömning av en hälsorisk i samband med serotoninbrist

Publications (3)

Publication Number Publication Date
FI20116007A0 FI20116007A0 (sv) 2011-10-12
FI20116007A FI20116007A (sv) 2013-04-13
FI126711B true FI126711B (sv) 2017-04-13

Family

ID=44883675

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20116007A FI126711B (sv) 2011-10-12 2011-10-12 Bedömning av en hälsorisk i samband med serotoninbrist

Country Status (4)

Country Link
US (1) US10087480B2 (sv)
EP (1) EP2766027B1 (sv)
FI (1) FI126711B (sv)
WO (1) WO2013054001A1 (sv)

Families Citing this family (16)

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US20150105651A1 (en) * 2013-10-16 2015-04-16 ZBH Enterprises, LLC Systems and methods for mri-based health management
WO2016036615A1 (en) * 2014-09-03 2016-03-10 California Institute Of Technology Microbe-based modulation of serotonin biosynthesis
CN104392086B (zh) * 2014-09-09 2017-11-24 广东工业大学 一种基于皮尔逊秩次变量相关系数的信号检测电路及方法
CA3006044A1 (en) * 2015-09-09 2017-03-16 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with cerebro-craniofacial health
JP6353478B2 (ja) * 2016-03-28 2018-07-04 日清食品ホールディングス株式会社 セロトニン分泌促進能力を有するビフィズス菌
US11224605B2 (en) 2016-05-19 2022-01-18 Glycom A/S Synthetic composition
DK3600364T3 (da) 2017-06-14 2020-08-31 4D Pharma Res Ltd Sammensætninger omfattende en bakteriestamme af slægten megasphaera og anvendelser deraf
US10941433B2 (en) 2017-06-15 2021-03-09 Iowa State University Research Foundation, Inc. Neurotransmitter transport in probiotics
WO2019060661A1 (en) 2017-09-22 2019-03-28 Iowa State University Research Foundation, Inc. PROBIOTIC COMPOSITIONS FOR THE PRODUCTION OF DOPAMINE
AU2018361591A1 (en) * 2017-11-02 2020-06-18 Gc Corporation Intraoral examination method using information on bacterial group related to clinical indexes
TW202038979A (zh) * 2018-12-12 2020-11-01 英商4D製藥研究有限公司 包含細菌菌株之組成物
US20220249526A1 (en) * 2019-06-12 2022-08-11 Glycom A/S Human milk oligosaccharides and compositions thereof for use in preventing, managing or treating symptoms related to migraine
CA3144072A1 (en) * 2019-06-27 2020-12-30 Holobiome, Inc. Therapeutic compositions and methods of using serotonin modulating microbiome-based interventions to treat serotonin-related diseases or disorders
IT201900011193A1 (it) * 2019-07-08 2021-01-08 Sofar Spa Ceppo di batteri Bifidobacterium bifidum, sue composizioni e relativi usi
EP3897836B1 (en) * 2019-11-08 2023-08-16 Biogaia AB Serotonin producing bacteria
CN114947134B (zh) * 2022-05-06 2024-01-26 河北一然生物科技股份有限公司 嗜热链球菌s131在改善肠道健康及调节肠道菌群中的应用

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JP2826808B2 (ja) * 1995-07-14 1998-11-18 カルピス株式会社 脳機能改善、学習能力増強および記憶力増強作用を有する機能性食品
US20040005304A1 (en) * 2002-07-08 2004-01-08 Mak Wood, Inc. Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions
FI112504B (sv) 2002-08-07 2003-12-15 Cyflo Oy Förfarande för identifiering av bakterier
US20040265279A1 (en) 2003-05-08 2004-12-30 Timothy Dinan Probiotics in the treatment of atypical depression and other disorders characterized by hypothalamic pitiuitary-adrenal axis over-activity
BRPI0514903A (pt) * 2004-09-03 2008-06-24 Hansens Lab proteìnas vegetais ou leite fermentado compreendendo ligando de receptor e uso dos mesmos
EP1974734A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Probiotics for reduction of risk of obesity
US8669267B2 (en) * 2008-08-21 2014-03-11 Suntory Holdings Limited Pharmaceutical, food or beverage having inhibitory activity on serotonin transporter
WO2011058535A1 (en) 2009-11-11 2011-05-19 Alimentary Health Limited Probiotic bifidobacterium strain
BR112012011294B1 (pt) * 2009-11-12 2018-03-20 Nestec S.A. Composição nutricional para administração a um indivíduo
KR101143997B1 (ko) 2010-03-04 2012-05-09 한미사이언스 주식회사 유산균 제제 및 5-ht4 수용체 효능제를 함유하는 경구 투여용 복합 제제 및 이의 제조방법

Also Published As

Publication number Publication date
EP2766027A4 (en) 2015-03-25
FI20116007A (sv) 2013-04-13
US20140301995A1 (en) 2014-10-09
EP2766027B1 (en) 2019-09-04
WO2013054001A1 (en) 2013-04-18
US10087480B2 (en) 2018-10-02
EP2766027A1 (en) 2014-08-20
FI20116007A0 (sv) 2011-10-12

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