FI118472B - Autoantigeenistä johdettuja uusia peptidejä autoimmuunitautien immunoterapiassa käyttöä varten - Google Patents

Autoantigeenistä johdettuja uusia peptidejä autoimmuunitautien immunoterapiassa käyttöä varten Download PDF

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Publication number
FI118472B
FI118472B FI962619A FI962619A FI118472B FI 118472 B FI118472 B FI 118472B FI 962619 A FI962619 A FI 962619A FI 962619 A FI962619 A FI 962619A FI 118472 B FI118472 B FI 118472B
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FI
Finland
Prior art keywords
seq
peptides
peptide
amino acid
cells
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FI962619A
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English (en)
Finnish (fi)
Swedish (sv)
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FI962619A0 (fi
FI962619A (fi
Inventor
Anna Maria Helena Boots
Gijsbertus Francisc Verheijden
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Organon Nv
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Publication of FI962619A0 publication Critical patent/FI962619A0/fi
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Rehabilitation Therapy (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI962619A 1994-10-27 1996-06-25 Autoantigeenistä johdettuja uusia peptidejä autoimmuunitautien immunoterapiassa käyttöä varten FI118472B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP94203128 1994-10-27
EP94203128 1994-10-27
EP95200886 1995-04-07
EP95200886 1995-04-07
EP9504201 1995-10-25
PCT/EP1995/004201 WO1996013517A1 (en) 1994-10-27 1995-10-25 Novel peptides derived from autoantigen for use in immunotherapy of autoimmune diseases

Publications (3)

Publication Number Publication Date
FI962619A0 FI962619A0 (fi) 1996-06-25
FI962619A FI962619A (fi) 1996-06-25
FI118472B true FI118472B (fi) 2007-11-30

Family

ID=26136688

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962619A FI118472B (fi) 1994-10-27 1996-06-25 Autoantigeenistä johdettuja uusia peptidejä autoimmuunitautien immunoterapiassa käyttöä varten

Country Status (24)

Country Link
US (1) US5736507A (es)
EP (1) EP0733065B1 (es)
JP (1) JP3755894B2 (es)
KR (1) KR100485979B1 (es)
CN (1) CN1161379C (es)
AT (1) ATE177756T1 (es)
AU (1) AU696827B2 (es)
BR (1) BR9506377A (es)
CA (1) CA2173874A1 (es)
DE (1) DE69508380T2 (es)
DK (1) DK0733065T3 (es)
ES (1) ES2130672T3 (es)
FI (1) FI118472B (es)
GR (1) GR3030296T3 (es)
HK (1) HK1002012A1 (es)
HU (1) HU218027B (es)
IL (1) IL115744A (es)
MX (1) MX9602495A (es)
NO (1) NO316703B1 (es)
NZ (1) NZ295659A (es)
PL (1) PL183761B1 (es)
RU (1) RU2178797C2 (es)
TR (1) TR199501326A2 (es)
WO (1) WO1996013517A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843449A (en) * 1996-03-25 1998-12-01 Akzo Nobel N.V. Proteins and novel peptides derived from autoantigen for use in immunotherapy of autoimmune diseases
US6881824B1 (en) 1996-04-24 2005-04-19 Akzo Nobel N.V. Peptides suitable for use in antigen specific immunosuppressive therapy
IL120561A0 (en) * 1996-04-24 1997-07-13 Akzo Nobel Nv Peptides suitable for use in immunosuppressive therapy
EP0947524A1 (en) * 1998-03-30 1999-10-06 Upither B.V. Novel peptides for the treatment of autoimmune diseases
CN1310724A (zh) * 1998-07-23 2001-08-29 阿克佐诺贝尔公司 用于自身免疫疾病的免疫疗法中的新型肽
WO2000004917A2 (en) * 1998-07-23 2000-02-03 Akzo Nobel N.V. USE OF HC gp-39 IN IMMUNE DISEASES
MXPA02003520A (es) * 1999-10-18 2002-08-20 Akzo Nobel Nv Imitaciones de peptido y peptidos modificados para utilizarse en inmunoterapia.
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
WO2003009808A2 (en) 2001-07-24 2003-02-06 Yale University Methods, compositions and kits relating to chitinases and chitinase-like molecules and inflammatory disease
EP1729805A4 (en) * 2004-02-25 2008-11-26 Medimmune Inc METHODS AND COMPOSITIONS RELATED TO CHITINASES AND CHITINASE-MOLECULARS AND MODULATION OF OSTEOCLASTS
WO2007027748A2 (en) * 2005-08-31 2007-03-08 Medimmune, Inc. C/clp antagonists and methods of use thereof
RU2302872C9 (ru) * 2006-06-22 2008-12-20 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Средство, нормализующее функции хрящевой ткани, и способ его получения
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
DK2190473T3 (da) 2007-08-15 2013-03-25 Circassia Ltd Peptid med reduceret dimerdannelse
WO2010018384A1 (en) * 2008-08-15 2010-02-18 Circassia Limited T-cell antigen peptide from allergen for stimulation of il-10 production
PT2153841E (pt) 2008-08-15 2012-03-21 Circassia Ltd Vacina compreendendo péptidos amb a 1 para utilização no tratamento de alergia a ambrósia
US8753644B2 (en) 2009-02-05 2014-06-17 Circassia Limited Grass peptides for vaccine
HUE029150T2 (hu) * 2009-10-27 2017-02-28 Erytech Pharma Készítmény specifikus immuntolerancia indukálására
WO2017041051A1 (en) 2015-09-04 2017-03-09 Sqz Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6323898A (ja) * 1986-07-16 1988-02-01 Dainippon Pharmaceut Co Ltd 新規ポリペプチド及びそれをコ−ドするdna並びにそれらの製法
IL92629A0 (en) * 1989-12-10 1990-08-31 Yeda Res & Dev Direct binding of t-cell epitopes to mhc gene products on intact living antigen presenting cells and the use thereof for identifying epitopes causing autoimmune diseases and pharmaceutical compositions for treating such diseases
CA2164498C (en) * 1993-07-09 2007-09-11 Paul A. Price Assay for ykl-40 as a marker for degradation of mammalian connective tissue matrices

Also Published As

Publication number Publication date
KR100485979B1 (ko) 2006-01-27
DE69508380D1 (de) 1999-04-22
PL183761B1 (pl) 2002-07-31
CN1168677A (zh) 1997-12-24
GR3030296T3 (en) 1999-09-30
HK1002012A1 (en) 1998-07-24
NO962695L (no) 1996-06-26
ES2130672T3 (es) 1999-07-01
FI962619A0 (fi) 1996-06-25
AU696827B2 (en) 1998-09-17
HU9601401D0 (en) 1996-07-29
HUT74847A (en) 1997-02-28
IL115744A0 (en) 1996-01-19
JPH09507861A (ja) 1997-08-12
KR960705848A (ko) 1996-11-08
WO1996013517A1 (en) 1996-05-09
CA2173874A1 (en) 1996-05-09
DE69508380T2 (de) 1999-09-09
EP0733065A1 (en) 1996-09-25
RU2178797C2 (ru) 2002-01-27
NO316703B1 (no) 2004-04-13
TR199501326A2 (tr) 1996-06-21
IL115744A (en) 2000-07-16
AU3925295A (en) 1996-05-23
EP0733065B1 (en) 1999-03-17
NO962695D0 (no) 1996-06-26
MX9602495A (es) 1997-05-31
PL315198A1 (en) 1996-10-14
ATE177756T1 (de) 1999-04-15
US5736507A (en) 1998-04-07
JP3755894B2 (ja) 2006-03-15
HU218027B (hu) 2000-05-28
NZ295659A (en) 1998-02-26
DK0733065T3 (da) 1999-10-11
FI962619A (fi) 1996-06-25
BR9506377A (pt) 1997-09-16
CN1161379C (zh) 2004-08-11

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