FI117288B - Menetelmä virusten inaktivoimiseksi - Google Patents

Menetelmä virusten inaktivoimiseksi Download PDF

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Publication number
FI117288B
FI117288B FI955690A FI955690A FI117288B FI 117288 B FI117288 B FI 117288B FI 955690 A FI955690 A FI 955690A FI 955690 A FI955690 A FI 955690A FI 117288 B FI117288 B FI 117288B
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FI
Finland
Prior art keywords
virus
type
radiation
compound
treatment
Prior art date
Application number
FI955690A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI955690A0 (fi
FI955690A (fi
Inventor
Bernard Horowitz
Bolanle Williams
Henrietta Margolis-Nunno
Sing N Chin
Original Assignee
New York Blood Ct Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by New York Blood Ct Inc filed Critical New York Blood Ct Inc
Publication of FI955690A0 publication Critical patent/FI955690A0/fi
Publication of FI955690A publication Critical patent/FI955690A/fi
Application granted granted Critical
Publication of FI117288B publication Critical patent/FI117288B/fi

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0023—Agression treatment or altering
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0066—Psoralene-activated UV-A photochemotherapy (PUVA-therapy), e.g. for treatment of psoriasis or eczema, extracorporeal photopheresis with psoralens or fucocoumarins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261—Methods of inactivation or attenuation
    • C12N2760/20263—Methods of inactivation or attenuation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32661—Methods of inactivation or attenuation
    • C12N2770/32663—Methods of inactivation or attenuation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10161—Methods of inactivation or attenuation
    • C12N2795/10163—Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
FI955690A 1993-05-28 1995-11-24 Menetelmä virusten inaktivoimiseksi FI117288B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6923593A 1993-05-28 1993-05-28
US6923593 1993-05-28
PCT/US1994/006077 WO1994028120A1 (fr) 1991-05-10 1994-05-27 Procede de sterilisation de compositions biologiques et produit ainsi obtenu
US9406077 1994-05-27

Publications (3)

Publication Number Publication Date
FI955690A0 FI955690A0 (fi) 1995-11-24
FI955690A FI955690A (fi) 1996-01-22
FI117288B true FI117288B (fi) 2006-08-31

Family

ID=22087612

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955690A FI117288B (fi) 1993-05-28 1995-11-24 Menetelmä virusten inaktivoimiseksi

Country Status (12)

Country Link
EP (1) EP0702719B1 (fr)
JP (1) JP3426237B2 (fr)
KR (1) KR100258377B1 (fr)
AT (1) ATE301186T1 (fr)
AU (1) AU696246B2 (fr)
CA (1) CA2163636C (fr)
DE (1) DE69434445T2 (fr)
ES (1) ES2247587T3 (fr)
FI (1) FI117288B (fr)
NO (1) NO954815L (fr)
WO (1) WO1994028120A1 (fr)
ZA (1) ZA943754B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077659A (en) * 1990-05-15 2000-06-20 New York Blood Center, Inc. Vitamin E and derivatives thereof prevent potassium ion leakage and other types of damage in red cells that are virus sterilized by phthalocyanines and light
DE69637181T2 (de) 1995-07-14 2008-04-17 Caf - Dcf Cvba - Scrl Vorrichtung zur inaktivierung von viralen verunreinigungen in blutprodukten
US6329136B1 (en) 1998-10-30 2001-12-11 The Regents Of The University Of California Method for laser inactivation of infectious agents
US7655252B2 (en) 1999-04-28 2010-02-02 The Regents Of The University Of Michigan Antimicrobial nanoemulsion compositions and methods
US6635676B2 (en) * 1999-04-28 2003-10-21 Regents Of The University Of Michigan Non-toxic antimicrobial compositions and methods of use
WO2001087357A2 (fr) * 2000-05-17 2001-11-22 The American National Red Cross Irradiation gamma de produits pharmaceutiques a base de proteine
JP2010209109A (ja) * 2001-06-25 2010-09-24 Regents Of The Univ Of Michigan 抗微生物ナノエマルジョンの組成物および方法
WO2003063902A2 (fr) * 2002-02-01 2003-08-07 Gambro, Inc. Inactivation du virus west nile et de l'agent pathogene de la malaria au moyen de photosensibilisants
AU2004216476B2 (en) 2003-02-27 2009-01-08 Takeda Pharmaceutical Company Limited Method for the validatable inactivation of pathogens in a biological fluid by irradiation
WO2009131606A2 (fr) * 2008-02-01 2009-10-29 Belanger Julie M Inactivation virale employant des agents réticulants et des détergents
US8613934B2 (en) 2004-03-22 2013-12-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cellular and viral inactivation
SI1737492T1 (sl) 2004-04-16 2013-04-30 Bredent Medical Gmbh & Co. Kg Pripravek za fotodinamično zatiranje mikroorganizmov in uporaba pripravka
PL1737492T3 (pl) 2004-04-16 2013-05-31 Bredent Medical Gmbh & Co Kg Preparat do fotodynamicznego zwalczania mikroorganizmów i zastosowanie preparatu
DE102006008613A1 (de) 2006-02-24 2007-08-30 Dade Behring Marburg Gmbh Stabilisierte Zubereitungen von Serin-Endopeptidasen, deren Herstellung und Verwendung
US8580192B2 (en) 2006-10-31 2013-11-12 Ethicon, Inc. Sterilization of polymeric materials
US8747872B2 (en) 2007-05-02 2014-06-10 The Regents Of The University Of Michigan Nanoemulsion therapeutic compositions and methods of using the same
EP2008669A1 (fr) * 2007-06-22 2008-12-31 Maco Pharma S.A. Appareil d'irradiation pour rendre inactif les pathogènes et/ou leucocytes dans un liquide biologique et processus correspondant
EP2376089B1 (fr) 2008-11-17 2018-03-14 The Regents of the University of Michigan Compositions de vaccins contre le cancer et leurs méthodes d' utilisation
US20130039943A1 (en) * 2010-05-03 2013-02-14 Bruno Rene Andre Novel method
EP2771038B1 (fr) * 2011-10-26 2018-10-10 Amgen Inc. Procédés de réduction ou d'élimination de la modification protéique et de la dégradation protéique générées à partir de l'exposition à la lumière uv
KR101936559B1 (ko) * 2016-07-13 2019-01-09 국립암센터 분해가능 연결자를 포함하는 광증감제-펩타이드 결합체 및 그를 포함하는 광역학 진단 또는 치료용 조성물
EP3986499A2 (fr) 2019-06-22 2022-04-27 Cerus Corporation Systèmes de traitement de fluides biologiques
EP3991179A1 (fr) 2019-06-28 2022-05-04 Cerus Corporation Système et procédés permettant de mettre en oeuvre un dispositif de traitement de fluide biologique
EP4268849A1 (fr) 2020-12-24 2023-11-01 National University Corporation Kobe University Procédé d'inactivation de virus utilisant une exposition ultraviolette

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049798A (en) * 1974-12-11 1977-09-20 William K. Bottomley Method for the treatment of Herpes Simplex
US4693981A (en) * 1983-12-20 1987-09-15 Advanced Genetics Research Institute Preparation of inactivated viral vaccines
JPS61275228A (ja) * 1985-03-14 1986-12-05 バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド 治療用タンパク組成物中のビ−ルスの光動的不活性化
JPH01175942A (ja) * 1987-12-28 1989-07-12 Sanyo Kokusaku Pulp Co Ltd 抗ウイルス性医薬用組成物
GB8817240D0 (en) * 1988-07-20 1988-08-24 Univ Salford Business Services Sterilising methods
US5232844A (en) * 1990-05-15 1993-08-03 New York Blood Center Photodynamic inactivation of viruses in cell-containing compositions
US5120649A (en) * 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
US5211944A (en) * 1990-10-12 1993-05-18 Shaman Pharmaceuticals, Inc. Proanthocyanidin polymers having antiviral activity and methods of obtaining same

Also Published As

Publication number Publication date
JPH11503601A (ja) 1999-03-30
NO954815D0 (no) 1995-11-27
WO1994028120A1 (fr) 1994-12-08
EP0702719A1 (fr) 1996-03-27
KR100258377B1 (ko) 2000-06-01
AU7048594A (en) 1994-12-20
ES2247587T3 (es) 2006-03-01
ATE301186T1 (de) 2005-08-15
NO954815L (no) 1996-01-26
DE69434445D1 (de) 2005-09-08
ZA943754B (en) 1995-02-09
KR960702864A (ko) 1996-05-23
DE69434445T2 (de) 2006-05-18
EP0702719B1 (fr) 2005-08-03
JP3426237B2 (ja) 2003-07-14
FI955690A0 (fi) 1995-11-24
FI955690A (fi) 1996-01-22
CA2163636C (fr) 2002-01-08
AU696246B2 (en) 1998-09-03
EP0702719A4 (fr) 1996-08-14
CA2163636A1 (fr) 1994-12-08

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