FI116793B - Menetelmä terapeuttisesti tehokkaan vasta-aineen, sen fragmentin tai johdannaisen tai peptidin, joka sitoutuu alfa4beta1:een, valitsemiseksi - Google Patents
Menetelmä terapeuttisesti tehokkaan vasta-aineen, sen fragmentin tai johdannaisen tai peptidin, joka sitoutuu alfa4beta1:een, valitsemiseksi Download PDFInfo
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- FI116793B FI116793B FI920899A FI920899A FI116793B FI 116793 B FI116793 B FI 116793B FI 920899 A FI920899 A FI 920899A FI 920899 A FI920899 A FI 920899A FI 116793 B FI116793 B FI 116793B
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US40238989A | 1989-09-01 | 1989-09-01 | |
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US9004978 | 1990-08-31 | ||
PCT/US1990/004978 WO1991003252A1 (en) | 1989-09-01 | 1990-08-31 | Inhibition of lymphocyte adherence to vascular endothelium utilizing a novel extracellular matrix receptor-ligand interaction |
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FI920899A0 FI920899A0 (fi) | 1992-02-28 |
FI116793B true FI116793B (fi) | 2006-02-28 |
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Application Number | Title | Priority Date | Filing Date |
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FI920899A FI116793B (fi) | 1989-09-01 | 1992-02-28 | Menetelmä terapeuttisesti tehokkaan vasta-aineen, sen fragmentin tai johdannaisen tai peptidin, joka sitoutuu alfa4beta1:een, valitsemiseksi |
FI20050941A FI118842B (fi) | 1989-09-01 | 2005-09-21 | Menetelmä terapeuttisesti tehokkaan aineen, joka sitoutuu alfa4beeta1:een, tai sen ligandin, valitsemiseksi käytettäväksi lymfosyyttien migraation inhiboimiseksi vaskulaaristen endoteelisolukerrosten |
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Application Number | Title | Priority Date | Filing Date |
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FI20050941A FI118842B (fi) | 1989-09-01 | 2005-09-21 | Menetelmä terapeuttisesti tehokkaan aineen, joka sitoutuu alfa4beeta1:een, tai sen ligandin, valitsemiseksi käytettäväksi lymfosyyttien migraation inhiboimiseksi vaskulaaristen endoteelisolukerrosten |
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EP (2) | EP1366769A1 (ko) |
JP (1) | JP3357359B2 (ko) |
KR (1) | KR100188459B1 (ko) |
AT (1) | ATE253642T1 (ko) |
AU (1) | AU654657B2 (ko) |
CA (1) | CA2065292C (ko) |
DD (1) | DD297562A5 (ko) |
DE (3) | DE122006000044I2 (ko) |
DK (1) | DK0489837T4 (ko) |
ES (1) | ES2210225T5 (ko) |
FI (2) | FI116793B (ko) |
GR (2) | GR1001372B (ko) |
IE (2) | IE20040028A1 (ko) |
IL (3) | IL95501A (ko) |
LU (1) | LU91273I2 (ko) |
NL (1) | NL300240I2 (ko) |
NZ (1) | NZ235131A (ko) |
PT (1) | PT95180A (ko) |
WO (1) | WO1991003252A1 (ko) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
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US5730978A (en) * | 1989-09-01 | 1998-03-24 | Fred Hutchinson Cancer Research Center | Inhibition of lymphocyte adherence with α4β1-specific antibodies |
US7238668B1 (en) | 1989-09-01 | 2007-07-03 | Fred Hutchinson Cancer Research Center | Inhibition of lymphocyte adherence with CS-1-peptides and fragments thereof |
US6033665A (en) * | 1989-09-27 | 2000-03-07 | Elan Pharmaceuticals, Inc. | Compositions and methods for modulating leukocyte adhesion to brain endothelial cells |
US5610148A (en) * | 1991-01-18 | 1997-03-11 | University College London | Macroscopically oriented cell adhesion protein for wound treatment |
US5629287A (en) * | 1991-01-18 | 1997-05-13 | University College London | Depot formulations |
AU3420693A (en) * | 1991-12-24 | 1993-07-28 | Fred Hutchinson Cancer Research Center | Competitive inhibition of high-avidity alpha4-beta1 receptor using tripeptide ldv |
ATE150319T1 (de) * | 1992-01-13 | 1997-04-15 | Biogen Inc | Behandlung von asthma |
US5871734A (en) * | 1992-01-13 | 1999-02-16 | Biogen, Inc. | Treatment for asthma with VLA-4 blocking agents |
US5932214A (en) * | 1994-08-11 | 1999-08-03 | Biogen, Inc. | Treatment for inflammatory bowel disease with VLA-4 blockers |
IL102646A (en) * | 1992-07-26 | 1996-05-14 | Yeda Res & Dev | Non-peptidic surrogates of the ldv sequence and pharmaceutical compositions comprising them |
USRE40811E1 (en) | 1992-11-13 | 2009-06-30 | Board Of Regents Of The University Of Washington | Peripheralization of hematopoietic stem cells |
NZ262615A (en) † | 1993-02-09 | 1996-02-27 | Biogen Inc | Treating insulin dependent diabetes (type i) with anti vla4 (very late antigen) antibodies |
EP0689609B2 (en) † | 1993-03-18 | 2005-04-13 | N.V. Innogenetics S.A. | Process for typing hla-b using specific primers and probes sets |
ZA947006B (en) * | 1993-09-15 | 1995-05-02 | Univ Emory | Method of inhibiting binding of reticulocytes to endothelium by interfering with vla-4/vcam-1 interactions |
US5821231A (en) * | 1993-12-06 | 1998-10-13 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using same |
US5770573A (en) * | 1993-12-06 | 1998-06-23 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using the same |
AU693143B2 (en) * | 1993-12-06 | 1998-06-25 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using the same |
US5936065A (en) * | 1993-12-06 | 1999-08-10 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using the same |
US7435802B2 (en) | 1994-01-25 | 2008-10-14 | Elan Pharaceuticals, Inc. | Humanized anti-VLA4 immunoglobulins |
DK1759709T3 (da) * | 1994-01-25 | 2013-06-10 | Elan Pharm Inc | Humaniserede antistoffer mod leukocytadhæsionsmolekyle VLA-4 |
US5840299A (en) * | 1994-01-25 | 1998-11-24 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
FR2724393A1 (fr) * | 1994-09-12 | 1996-03-15 | Inst Nat Sante Rech Med | Obtention d'un anticorps monoclonal recombinant humanise a partir d'un anticorps monoclonal murin, sa production en cellules d'insecte, et ses utilisations |
WO1997035557A1 (en) * | 1996-03-22 | 1997-10-02 | Kao Corporation | External skin-care composition |
US7147851B1 (en) | 1996-08-15 | 2006-12-12 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with α4β7 integrin |
MY157727A (en) | 2002-02-25 | 2016-07-15 | Biogen Idec Inc | Administration of agents for the treatment of inflamation |
US7125650B2 (en) | 2004-07-20 | 2006-10-24 | Roberts David H | Method for bump exposing relief image printing plates |
UA116189C2 (uk) | 2011-05-02 | 2018-02-26 | Мілленніум Фармасьютікалз, Інк. | КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА |
WO2012151247A2 (en) | 2011-05-02 | 2012-11-08 | Millennium Pharmaceuticals, Inc. | FORMULATION FOR ANTI-α4β7 ANTIBODY |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4578079A (en) * | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
WO1990008833A1 (en) * | 1989-02-02 | 1990-08-09 | Massachusetts Institute Of Technology | Expression of recombinant fibronectin in genetically engineered cells |
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1990
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- 1990-08-31 AT AT90913598T patent/ATE253642T1/de active
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- 1990-08-31 EP EP20030017578 patent/EP1366769A1/en not_active Withdrawn
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- 1990-08-31 EP EP90913598.0A patent/EP0489837B2/en not_active Expired - Lifetime
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1992
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