FI113863B - Indolijohdannaiset 5-HT1-tyyppisinä agonisteina - Google Patents
Indolijohdannaiset 5-HT1-tyyppisinä agonisteina Download PDFInfo
- Publication number
- FI113863B FI113863B FI971492A FI971492A FI113863B FI 113863 B FI113863 B FI 113863B FI 971492 A FI971492 A FI 971492A FI 971492 A FI971492 A FI 971492A FI 113863 B FI113863 B FI 113863B
- Authority
- FI
- Finland
- Prior art keywords
- pharmaceutically acceptable
- formula
- compound
- pyrrolidinylmethyl
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9420503A GB9420503D0 (en) | 1994-10-11 | 1994-10-11 | Therapeutic agents |
GB9420503 | 1994-10-11 | ||
EP9503884 | 1995-09-29 | ||
PCT/EP1995/003884 WO1996011195A1 (en) | 1994-10-11 | 1995-09-29 | Indole derivatives as 5ht1-like agonists |
Publications (3)
Publication Number | Publication Date |
---|---|
FI971492A0 FI971492A0 (fi) | 1997-04-10 |
FI971492A FI971492A (fi) | 1997-04-10 |
FI113863B true FI113863B (fi) | 2004-06-30 |
Family
ID=10762688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI971492A FI113863B (fi) | 1994-10-11 | 1997-04-10 | Indolijohdannaiset 5-HT1-tyyppisinä agonisteina |
Country Status (11)
Country | Link |
---|---|
US (1) | US5770611A (ja) |
EP (1) | EP0785933B1 (ja) |
JP (1) | JP2902484B2 (ja) |
AT (1) | ATE163934T1 (ja) |
DE (1) | DE69501791T2 (ja) |
DK (1) | DK0785933T3 (ja) |
ES (1) | ES2113213T3 (ja) |
FI (1) | FI113863B (ja) |
GB (1) | GB9420503D0 (ja) |
GR (1) | GR3026532T3 (ja) |
WO (1) | WO1996011195A1 (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9420529D0 (en) | 1994-10-12 | 1994-11-30 | Pfizer Ltd | Indoles |
KR100540046B1 (ko) | 1997-11-12 | 2006-01-10 | 미쓰비시 가가꾸 가부시키가이샤 | 퓨린유도체 및 이를 유효성분으로 함유하는 의약 |
KR20010052503A (ko) | 1998-06-03 | 2001-06-25 | 다니엘 피. 맥컬럼 | N-헤테로사이클릭 카복실산 또는 카복실산 등입체의n-결합된 설폰아미드 |
ES2206227T3 (es) * | 1999-05-11 | 2004-05-16 | Mitsubishi Chemical Corporation | Dihidrato de un derivado de purina, farmacos que lo contienen como ingrediente activo, e intermedio en su preparacion. |
WO2011158149A1 (en) | 2010-06-18 | 2011-12-22 | Pfizer Inc. | 2-(3,5-disubstitutedphenyl)pyrimidin-4(3h)-one derivatives |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5559246A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc. | Indole derivatives |
US5578612A (en) * | 1990-10-15 | 1996-11-26 | Pfizer Inc. | Indole derivatives |
US5607951A (en) * | 1990-10-15 | 1997-03-04 | Pfizer Inc | Indole derivatives |
US5545644A (en) * | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
US5559129A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc | Indole derivatives |
ES2143992T3 (es) * | 1991-11-25 | 2000-06-01 | Pfizer | Derivados de 5-(hetero- o carbociclilamino)-indol, su preparacion y uso como 5-ht1 agonistas. |
US5409941A (en) * | 1992-02-03 | 1995-04-25 | Pfizer Inc. | 5-heteroyl indole derivatives |
TW288010B (ja) * | 1992-03-05 | 1996-10-11 | Pfizer | |
GB9207930D0 (en) * | 1992-04-10 | 1992-05-27 | Pfizer Ltd | Indoles |
KR0179074B1 (ko) * | 1992-04-10 | 1999-03-20 | 알렌 제이. 스피겔 | 5-ht1 작용물질로서의 아실아미노인돌 유도체 |
GB9208161D0 (en) * | 1992-04-14 | 1992-05-27 | Pfizer Ltd | Indoles |
CN1121348A (zh) * | 1993-04-22 | 1996-04-24 | 辉瑞研究及发展公司 | 吲哚衍生物作为5-ht1类激动剂用于治疗周期性偏头痛 |
GB9424471D0 (en) * | 1994-12-03 | 1995-01-18 | Pfizer Ltd | Treatment of emesis |
-
1994
- 1994-10-11 GB GB9420503A patent/GB9420503D0/en active Pending
-
1995
- 1995-09-29 WO PCT/EP1995/003884 patent/WO1996011195A1/en active IP Right Grant
- 1995-09-29 DE DE69501791T patent/DE69501791T2/de not_active Expired - Fee Related
- 1995-09-29 US US08/809,600 patent/US5770611A/en not_active Expired - Fee Related
- 1995-09-29 EP EP95934124A patent/EP0785933B1/en not_active Expired - Lifetime
- 1995-09-29 ES ES95934124T patent/ES2113213T3/es not_active Expired - Lifetime
- 1995-09-29 AT AT95934124T patent/ATE163934T1/de not_active IP Right Cessation
- 1995-09-29 DK DK95934124.9T patent/DK0785933T3/da active
- 1995-09-29 JP JP8512312A patent/JP2902484B2/ja not_active Expired - Fee Related
-
1997
- 1997-04-10 FI FI971492A patent/FI113863B/fi active
-
1998
- 1998-04-03 GR GR980400716T patent/GR3026532T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
MX9702643A (es) | 1997-07-31 |
US5770611A (en) | 1998-06-23 |
DE69501791T2 (de) | 1998-07-02 |
WO1996011195A1 (en) | 1996-04-18 |
DK0785933T3 (da) | 1998-05-11 |
EP0785933B1 (en) | 1998-03-11 |
ATE163934T1 (de) | 1998-03-15 |
GB9420503D0 (en) | 1994-11-23 |
DE69501791D1 (de) | 1998-04-16 |
GR3026532T3 (en) | 1998-07-31 |
FI971492A0 (fi) | 1997-04-10 |
JPH09512034A (ja) | 1997-12-02 |
JP2902484B2 (ja) | 1999-06-07 |
ES2113213T3 (es) | 1998-04-16 |
EP0785933A1 (en) | 1997-07-30 |
FI971492A (fi) | 1997-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer of assignment of patent |
Owner name: PFEIZER IRELAND PHARMACEUTICALS Free format text: PFEIZER IRELAND PHARMACEUTICALS |