FI109687B - Menetelmä uusien D-vitamiinianalogien valmistamiseksi - Google Patents

Menetelmä uusien D-vitamiinianalogien valmistamiseksi Download PDF

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Publication number
FI109687B
FI109687B FI951968A FI951968A FI109687B FI 109687 B FI109687 B FI 109687B FI 951968 A FI951968 A FI 951968A FI 951968 A FI951968 A FI 951968A FI 109687 B FI109687 B FI 109687B
Authority
FI
Finland
Prior art keywords
compound
triene
tert
pregna
seco
Prior art date
Application number
FI951968A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI951968A (fi
FI951968A0 (fi
Inventor
Martin John Calverley
Henrik Pedersen
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of FI951968A publication Critical patent/FI951968A/fi
Publication of FI951968A0 publication Critical patent/FI951968A0/fi
Application granted granted Critical
Publication of FI109687B publication Critical patent/FI109687B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI951968A 1992-11-04 1995-04-25 Menetelmä uusien D-vitamiinianalogien valmistamiseksi FI109687B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9223061 1992-11-04
GB929223061A GB9223061D0 (en) 1992-11-04 1992-11-04 Chemical compounds
DK9300351 1993-11-01
PCT/DK1993/000351 WO1994010139A1 (fr) 1992-11-04 1993-11-01 Nouveaux analogues de la vitamine d

Publications (3)

Publication Number Publication Date
FI951968A FI951968A (fi) 1995-04-25
FI951968A0 FI951968A0 (fi) 1995-04-25
FI109687B true FI109687B (fi) 2002-09-30

Family

ID=10724491

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951968A FI109687B (fi) 1992-11-04 1995-04-25 Menetelmä uusien D-vitamiinianalogien valmistamiseksi

Country Status (16)

Country Link
US (1) US5710142A (fr)
EP (1) EP0667856B1 (fr)
JP (1) JPH08503700A (fr)
KR (1) KR100301214B1 (fr)
AT (1) ATE163007T1 (fr)
AU (1) AU671326B2 (fr)
CA (1) CA2144161A1 (fr)
DE (1) DE69316910T2 (fr)
DK (1) DK0667856T3 (fr)
ES (1) ES2114619T3 (fr)
FI (1) FI109687B (fr)
GB (1) GB9223061D0 (fr)
GR (1) GR3026647T3 (fr)
NZ (1) NZ257533A (fr)
RU (1) RU2128168C1 (fr)
WO (1) WO1994010139A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9314400D0 (en) * 1993-07-12 1993-08-25 Leo Pharm Prod Ltd Produktionsaktieselskab) chemical compounds
US6103709A (en) * 1993-12-23 2000-08-15 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs and methods for treatment of vitamin D diseases
US6121469A (en) 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
GB9611603D0 (en) 1996-06-04 1996-08-07 Leo Pharm Prod Ltd Chemical compounds
GB9622590D0 (en) * 1996-10-30 1997-01-08 Leo Pharm Prod Ltd Chemical compounds
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
CA2458415C (fr) * 2001-08-22 2010-09-21 Johns Hopkins University Analogues substitues par le soufre 24 de la 1.alpha.,25 dihydroxy-vitamine d3
JP4490262B2 (ja) 2002-06-13 2010-06-23 ジョンズ ホプキンス ユニバーシティ ２４−スルホキシイミンビタミンｄ３化合物
US8106035B2 (en) 2002-12-18 2012-01-31 Cytochroma Inc. 25-SO2-substituted analogs of 1μ,25-dihydroxyvitamin D3
US8404667B2 (en) * 2006-12-29 2013-03-26 Wisconsin Alumni Research Foundation Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
WO2006051106A1 (fr) 2004-11-12 2006-05-18 Bioxell Spa Emploi combiné de dérivés de vitamine d et d'agents antiproliférants pour le traitement de cancers de la vessie
US8425784B2 (en) * 2007-11-05 2013-04-23 University Of Kansas Ozonolysis reactions in liquid CO2 and CO2-expanded solvents
SG173119A1 (en) * 2009-01-27 2011-08-29 Berg Biosystems Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
BR112012003372A2 (pt) 2009-08-14 2019-09-24 Berg Biosystems Llc vitamina d3 e análogos da mesma para o tratamento de alopecia.
EP3003497B1 (fr) 2013-05-29 2024-02-14 BPGbio, Inc. Prévention ou atténuation de l'alopécie induite par la chimiothérapie au moyen de vitamine d

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4617297A (en) * 1982-02-12 1986-10-14 Hoffmann-La Roche Inc. Method of treating disease states by the administration of 1α,25,26-trihydroxycholecalciferol
US4594432A (en) * 1983-01-28 1986-06-10 Hoffman-La Roche Inc. Process for the synthesis of 1α,23(S),25-trihydroxycholecalciferol and 1α,23(R),25-trihydroxycholecalciferol
US4719205A (en) * 1984-01-30 1988-01-12 Wisconsin Alumini Research Foundation Side-chain unsaturated 1-hydroxyvitamin D compounds
JPS6144860A (ja) * 1984-08-10 1986-03-04 Taisho Pharmaceut Co Ltd １α．２５−ジヒドロキシ−２６．２７−ジメチルビタミンＤ↓３
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
EP0205285B1 (fr) * 1985-05-30 1989-08-09 Taisho Pharmaceutical Co. Ltd Dérivés de vitamine D3
US4832875A (en) * 1985-11-21 1989-05-23 Taisho Pharmaceutical Co., Ltd. Vitamin D3 derivative
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
US4851401A (en) * 1988-07-14 1989-07-25 Wisconsin Alumni Research Foundation Novel cyclopentano-vitamin D analogs
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
IL97158A (en) * 1990-02-06 1994-12-29 Schering Ag Homologous histories of vitamin D in the side chain, processes for their preparation and pharmaceutical preparations containing them
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
DE4011682A1 (de) * 1990-04-06 1991-10-10 Schering Ag 24-oxa-derivate in der vitamin d-reihe
US5200536A (en) * 1992-02-10 1993-04-06 Daikin Industries Ltd. Fluorine-containing vitamin D3 analogues
US5194431A (en) * 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives

Also Published As

Publication number Publication date
FI951968A (fi) 1995-04-25
WO1994010139A1 (fr) 1994-05-11
ATE163007T1 (de) 1998-02-15
NZ257533A (en) 1997-06-24
RU2128168C1 (ru) 1999-03-27
CA2144161A1 (fr) 1994-05-11
FI951968A0 (fi) 1995-04-25
AU5418194A (en) 1994-05-24
GB9223061D0 (en) 1992-12-16
JPH08503700A (ja) 1996-04-23
DE69316910D1 (de) 1998-03-12
EP0667856B1 (fr) 1998-02-04
AU671326B2 (en) 1996-08-22
KR100301214B1 (ko) 2001-11-22
GR3026647T3 (en) 1998-07-31
DK0667856T3 (da) 1998-09-28
DE69316910T2 (de) 1998-10-01
US5710142A (en) 1998-01-20
EP0667856A1 (fr) 1995-08-23
RU95113157A (ru) 1996-11-20
ES2114619T3 (es) 1998-06-01

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