DK0667856T3 - Nye D-vitaminanaloger - Google Patents

Nye D-vitaminanaloger

Info

Publication number
DK0667856T3
DK0667856T3 DK93924535T DK93924535T DK0667856T3 DK 0667856 T3 DK0667856 T3 DK 0667856T3 DK 93924535 T DK93924535 T DK 93924535T DK 93924535 T DK93924535 T DK 93924535T DK 0667856 T3 DK0667856 T3 DK 0667856T3
Authority
DK
Denmark
Prior art keywords
pct
date
analogs
sec
compounds
Prior art date
Application number
DK93924535T
Other languages
English (en)
Inventor
Martin John Calverley
Henrik Pedersen
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Application granted granted Critical
Publication of DK0667856T3 publication Critical patent/DK0667856T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK93924535T 1992-11-04 1993-11-01 Nye D-vitaminanaloger DK0667856T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929223061A GB9223061D0 (en) 1992-11-04 1992-11-04 Chemical compounds
PCT/DK1993/000351 WO1994010139A1 (en) 1992-11-04 1993-11-01 Novel vitamin d analogues

Publications (1)

Publication Number Publication Date
DK0667856T3 true DK0667856T3 (da) 1998-09-28

Family

ID=10724491

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93924535T DK0667856T3 (da) 1992-11-04 1993-11-01 Nye D-vitaminanaloger

Country Status (16)

Country Link
US (1) US5710142A (da)
EP (1) EP0667856B1 (da)
JP (1) JPH08503700A (da)
KR (1) KR100301214B1 (da)
AT (1) ATE163007T1 (da)
AU (1) AU671326B2 (da)
CA (1) CA2144161A1 (da)
DE (1) DE69316910T2 (da)
DK (1) DK0667856T3 (da)
ES (1) ES2114619T3 (da)
FI (1) FI109687B (da)
GB (1) GB9223061D0 (da)
GR (1) GR3026647T3 (da)
NZ (1) NZ257533A (da)
RU (1) RU2128168C1 (da)
WO (1) WO1994010139A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9314400D0 (en) * 1993-07-12 1993-08-25 Leo Pharm Prod Ltd Produktionsaktieselskab) chemical compounds
US6103709A (en) * 1993-12-23 2000-08-15 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs and methods for treatment of vitamin D diseases
US6121469A (en) 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
GB9611603D0 (en) 1996-06-04 1996-08-07 Leo Pharm Prod Ltd Chemical compounds
GB9622590D0 (en) * 1996-10-30 1997-01-08 Leo Pharm Prod Ltd Chemical compounds
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
CA2458415C (en) * 2001-08-22 2010-09-21 Johns Hopkins University 24-sulfur-substituted analogs of 1.alpha.,25-dihydroxy vitamin d3
JP4490262B2 (ja) 2002-06-13 2010-06-23 ジョンズ ホプキンス ユニバーシティ 24−スルホキシイミンビタミンd3化合物
US8106035B2 (en) 2002-12-18 2012-01-31 Cytochroma Inc. 25-SO2-substituted analogs of 1μ,25-dihydroxyvitamin D3
US8404667B2 (en) * 2006-12-29 2013-03-26 Wisconsin Alumni Research Foundation Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
US8425784B2 (en) * 2007-11-05 2013-04-23 University Of Kansas Ozonolysis reactions in liquid CO2 and CO2-expanded solvents
SG173119A1 (en) * 2009-01-27 2011-08-29 Berg Biosystems Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
BR112012003372A2 (pt) 2009-08-14 2019-09-24 Berg Biosystems Llc vitamina d3 e análogos da mesma para o tratamento de alopecia.
EP3003497B1 (en) 2013-05-29 2024-02-14 BPGbio, Inc. Preventing or mitigating chemotherapy induced alopecia using vitamin d

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4617297A (en) * 1982-02-12 1986-10-14 Hoffmann-La Roche Inc. Method of treating disease states by the administration of 1α,25,26-trihydroxycholecalciferol
US4594432A (en) * 1983-01-28 1986-06-10 Hoffman-La Roche Inc. Process for the synthesis of 1α,23(S),25-trihydroxycholecalciferol and 1α,23(R),25-trihydroxycholecalciferol
US4719205A (en) * 1984-01-30 1988-01-12 Wisconsin Alumini Research Foundation Side-chain unsaturated 1-hydroxyvitamin D compounds
JPS6144860A (ja) * 1984-08-10 1986-03-04 Taisho Pharmaceut Co Ltd 1α.25−ジヒドロキシ−26.27−ジメチルビタミンD↓3
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
EP0205285B1 (en) * 1985-05-30 1989-08-09 Taisho Pharmaceutical Co. Ltd Vitamin d3 derivatives
US4832875A (en) * 1985-11-21 1989-05-23 Taisho Pharmaceutical Co., Ltd. Vitamin D3 derivative
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
US4851401A (en) * 1988-07-14 1989-07-25 Wisconsin Alumni Research Foundation Novel cyclopentano-vitamin D analogs
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
IL97158A (en) * 1990-02-06 1994-12-29 Schering Ag Homologous histories of vitamin D in the side chain, processes for their preparation and pharmaceutical preparations containing them
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
DE4011682A1 (de) * 1990-04-06 1991-10-10 Schering Ag 24-oxa-derivate in der vitamin d-reihe
US5200536A (en) * 1992-02-10 1993-04-06 Daikin Industries Ltd. Fluorine-containing vitamin D3 analogues
US5194431A (en) * 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives

Also Published As

Publication number Publication date
FI951968A (fi) 1995-04-25
WO1994010139A1 (en) 1994-05-11
ATE163007T1 (de) 1998-02-15
NZ257533A (en) 1997-06-24
RU2128168C1 (ru) 1999-03-27
CA2144161A1 (en) 1994-05-11
FI951968A0 (fi) 1995-04-25
AU5418194A (en) 1994-05-24
GB9223061D0 (en) 1992-12-16
JPH08503700A (ja) 1996-04-23
DE69316910D1 (de) 1998-03-12
EP0667856B1 (en) 1998-02-04
AU671326B2 (en) 1996-08-22
KR100301214B1 (ko) 2001-11-22
GR3026647T3 (en) 1998-07-31
DE69316910T2 (de) 1998-10-01
US5710142A (en) 1998-01-20
EP0667856A1 (en) 1995-08-23
RU95113157A (ru) 1996-11-20
ES2114619T3 (es) 1998-06-01
FI109687B (fi) 2002-09-30

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