FI109577B - Kompositmembraner och förfarande för framställning av detta - Google Patents
Kompositmembraner och förfarande för framställning av detta Download PDFInfo
- Publication number
- FI109577B FI109577B FI942895A FI942895A FI109577B FI 109577 B FI109577 B FI 109577B FI 942895 A FI942895 A FI 942895A FI 942895 A FI942895 A FI 942895A FI 109577 B FI109577 B FI 109577B
- Authority
- FI
- Finland
- Prior art keywords
- hyaluronic acid
- ester
- acid ester
- hours
- groups
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/10—Hair or skin implants
- A61F2/105—Skin implants, e.g. artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/041—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
- Y10T428/24058—Structurally defined web or sheet [e.g., overall dimension, etc.] including grain, strips, or filamentary elements in respective layers or components in angular relation
- Y10T428/24124—Fibers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
- Y10T442/10—Scrim [e.g., open net or mesh, gauze, loose or open weave or knit, etc.]
- Y10T442/102—Woven scrim
- Y10T442/172—Coated or impregnated
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Materials Engineering (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Composite Materials (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Claims (6)
1. Ett kompositmembran, som omfattar ett förstärkningsnät infällt i en polymermatris, kännetecknat av att 5 förstärkningsnätet omfattar ätminstone ett fibermaterial, som är valt ur en grupp bestäende av hyaluronsyraesterfibrer samt en kombination av hyaluronester- och alginsyraesterfibrer och nämnda material omfattar ätminstone ett material som är valt ur en grupp, som omfattar hyaluronsyraester, alginsyra och 10 gelbildad polysackarid.
2. Ett kompositmembran enligt krav 1, kännetecknat av att kompositmembranet omfattar en blandning av hyaluron-syraestrar, alginsyraestrar och ätminstone en gelbildad 15 polysackarid, som är vald ur en grupp, som omfattar kitin, alginat, kitosan, gellan, och ett syntetiskt derivat därav eller ett halvsyntetiskt derivat därav. v.
3 Ett kompositmembran enligt krav 1, kännetecknat 20 av att dess basvikt är ca 8 - 50 g/cm2, tjocklek ca 0,08 - ; , 0,5 mm, minimidragbrottstyrka som torr ca 100 - 500 kg/cm2, töjning som torr ca 3 - 12 %, minimidragbrottstyrka som vät ’ ca 30 - 450 kg/cm2, töjning som vät 20 - 60 %, rivhällfasthet som torr ca 40 - 200 kg/cm2 och rivhällfasthet som vät ca 20 : 25 - 160 kg/cm2.
4. Ett kompositmembran enligt krav 1, kännetecknat >”; av att förstärkningsnätet omfattar ett multifilament-nät, som ,‘ , omfattar flerdubbla trädar, som har ca 30 - 120 tätar, vars 30 diameter är ca 18 - 35 mikroner, varvid trädens deniertal är ca 150 - 400, och multifilamenten är vridna ca 90 - 200 :Y: gänger per meter och nätet är bearbetat tili ett vävt tyg, vars densitet är ca 10 - 16. 35
5. Förfarande för framställning av kompositmembran enligt patentkrav 1 eller 2, kännetecknat av att ett förstärkningsnät formas, vilket omfattar en hyaluronsyraester eller en alginsyraester, som har en farmakologiskt aktiv 109577 49 eller inaktiv alkohol, och pä nämnda förstärkningsnät utbreds en matris, som innehäller en hyaluronsyraester eller en alginsyraester, som har en farmakologiskt aktiv eller inaktiv alkohol, och valbart ätminstone en gelbildad polysackarid. 5
6. Förfarande för framställning av en kompositmembran, kännetecknat av att ett förstärkningsnät formas, som omfattar ätminstone ett material som är vald ur en grupp, som bestär av hyaluronsyraestrar och alginsyraestrar, och pä 10 nämnda förstärkningsnät utbreds en matris som omfattar ätminstone ett material, som är valt ur en grupp som omfattar hyaluronsyraester, alginsyraester och gelbildad polysackarid.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITPD910228A IT1254170B (it) | 1991-12-18 | 1991-12-18 | Membrane composite per la rigenerazione guidata di tessuti |
ITPD910228 | 1991-12-18 | ||
EP9202959 | 1992-12-18 | ||
PCT/EP1992/002959 WO1993011805A1 (en) | 1991-12-18 | 1992-12-18 | Composite membranes for the guided regeneration of tissues |
Publications (3)
Publication Number | Publication Date |
---|---|
FI942895A0 FI942895A0 (sv) | 1994-06-16 |
FI942895A FI942895A (sv) | 1994-08-18 |
FI109577B true FI109577B (sv) | 2002-09-13 |
Family
ID=11389748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI942895A FI109577B (sv) | 1991-12-18 | 1994-06-16 | Kompositmembraner och förfarande för framställning av detta |
Country Status (20)
Country | Link |
---|---|
US (1) | US5622707A (sv) |
EP (1) | EP0625056B1 (sv) |
JP (1) | JP3277212B2 (sv) |
KR (1) | KR100252192B1 (sv) |
AT (1) | ATE185699T1 (sv) |
AU (1) | AU669148B2 (sv) |
BG (1) | BG61596B1 (sv) |
CA (1) | CA2126087C (sv) |
DE (1) | DE69230182T2 (sv) |
DK (1) | DK0625056T3 (sv) |
ES (1) | ES2141145T3 (sv) |
FI (1) | FI109577B (sv) |
GR (1) | GR3032451T3 (sv) |
HU (1) | HU217989B (sv) |
IT (1) | IT1254170B (sv) |
NO (1) | NO308724B1 (sv) |
NZ (1) | NZ246576A (sv) |
RO (1) | RO111200B1 (sv) |
RU (1) | RU2128057C1 (sv) |
WO (1) | WO1993011805A1 (sv) |
Families Citing this family (83)
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FR2679778B1 (fr) * | 1991-08-02 | 1995-07-07 | Coletica | Utilisation de collagene reticule par un agent de reticulation pour la fabrication d'une membrane suturable, biocompatible, a resorption lente, ainsi qu'une telle membrane. |
US5879359A (en) * | 1992-08-03 | 1999-03-09 | Fidia S.P.A. | Biodegradable guide channels comprised of esters of hyaluronic acid for use in tissue repair as surgical aids |
IT1259141B (it) * | 1992-08-03 | 1996-03-11 | Fidia Spa | Canali di guida biodegradabili e bioriassorbibili da impiegare per la riparazione tissutale come adiuvante in interventi chirurgici |
US5616568A (en) * | 1993-11-30 | 1997-04-01 | The Research Foundation Of State University Of New York | Functionalized derivatives of hyaluronic acid |
WO1997007833A2 (en) | 1995-08-29 | 1997-03-06 | Fidia Advanced Biopolymers, S.R.L. | Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives |
DE69836461T2 (de) * | 1997-04-04 | 2007-09-13 | KURARAY CO., LTD, Kurashiki | Therapeutisches material für periodontitis |
FR2766716B1 (fr) * | 1997-08-01 | 2000-02-18 | Cogent Sarl | Prothese composite pour la prevention des adherences post-chirurgicales et son procede d'obtention |
JP4234803B2 (ja) | 1997-10-27 | 2009-03-04 | 久光製薬株式会社 | 薬物放出速度が制御された医薬組成物 |
US6872819B1 (en) * | 1998-05-27 | 2005-03-29 | Fidia Advanced Biopolymers S.R.L. | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells |
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US4280954A (en) * | 1975-07-15 | 1981-07-28 | Massachusetts Institute Of Technology | Crosslinked collagen-mucopolysaccharide composite materials |
GB2103993B (en) * | 1981-08-18 | 1985-03-27 | David Philip Tong | Production of alginate fibre |
IN163192B (sv) * | 1983-10-11 | 1988-08-20 | Fidia Spa | |
US4851521A (en) * | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
IT1214658B (it) * | 1985-07-08 | 1990-01-18 | Fidia Farmaceutici | Esteri polisaccaridici e loro sali |
US5147861A (en) * | 1986-06-30 | 1992-09-15 | Fidia S.P.A. | Esters of alginic acid |
IT1203814B (it) * | 1986-06-30 | 1989-02-23 | Fidia Farmaceutici | Esteri dell'acido alginico |
IT1198449B (it) * | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
FR2616318A1 (fr) * | 1987-06-15 | 1988-12-16 | Centre Nat Rech Scient | Peau artificielle et son procede de preparation |
IT1219587B (it) * | 1988-05-13 | 1990-05-18 | Fidia Farmaceutici | Polisaccaridi carbossiilici autoreticolati |
JPH0622560B2 (ja) * | 1989-04-11 | 1994-03-30 | 株式会社紀文食品 | ヒアルロン酸塩シートの製造方法 |
WO1991017744A1 (en) * | 1990-05-14 | 1991-11-28 | Jernberg Gary R | Surgical implant and method incorporating chemotherapeutic agents |
IT1247157B (it) * | 1991-02-11 | 1994-12-12 | Fidia Spa | Canali di guida biodegradabili e bioassorbibili da impiegare per la rigenerazione nervosa. |
-
1991
- 1991-12-18 IT ITPD910228A patent/IT1254170B/it active
-
1992
- 1992-12-18 US US07/992,697 patent/US5622707A/en not_active Expired - Lifetime
- 1992-12-18 DK DK93902121T patent/DK0625056T3/da active
- 1992-12-18 AT AT93902121T patent/ATE185699T1/de active
- 1992-12-18 NZ NZ246576A patent/NZ246576A/en unknown
- 1992-12-18 CA CA002126087A patent/CA2126087C/en not_active Expired - Lifetime
- 1992-12-18 RU RU94030735A patent/RU2128057C1/ru active
- 1992-12-18 RO RO94-01046A patent/RO111200B1/ro unknown
- 1992-12-18 AU AU33467/93A patent/AU669148B2/en not_active Expired
- 1992-12-18 ES ES93902121T patent/ES2141145T3/es not_active Expired - Lifetime
- 1992-12-18 DE DE69230182T patent/DE69230182T2/de not_active Expired - Lifetime
- 1992-12-18 HU HU9401838A patent/HU217989B/hu unknown
- 1992-12-18 WO PCT/EP1992/002959 patent/WO1993011805A1/en active IP Right Grant
- 1992-12-18 JP JP51064293A patent/JP3277212B2/ja not_active Expired - Fee Related
- 1992-12-18 EP EP93902121A patent/EP0625056B1/en not_active Expired - Lifetime
- 1992-12-18 KR KR1019940702108A patent/KR100252192B1/ko not_active IP Right Cessation
-
1994
- 1994-06-16 FI FI942895A patent/FI109577B/sv not_active IP Right Cessation
- 1994-06-17 NO NO942329A patent/NO308724B1/no not_active IP Right Cessation
- 1994-06-17 BG BG98862A patent/BG61596B1/bg unknown
-
2000
- 2000-01-21 GR GR20000400146T patent/GR3032451T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0625056A1 (en) | 1994-11-23 |
WO1993011805A1 (en) | 1993-06-24 |
ATE185699T1 (de) | 1999-11-15 |
KR100252192B1 (ko) | 2000-06-01 |
ITPD910228A0 (it) | 1991-12-18 |
ES2141145T3 (es) | 2000-03-16 |
CA2126087A1 (en) | 1993-06-24 |
ITPD910228A1 (it) | 1993-06-18 |
JPH07502431A (ja) | 1995-03-16 |
BG61596B1 (bg) | 1998-01-30 |
DK0625056T3 (da) | 2000-03-27 |
US5622707A (en) | 1997-04-22 |
NO308724B1 (no) | 2000-10-23 |
RU2128057C1 (ru) | 1999-03-27 |
JP3277212B2 (ja) | 2002-04-22 |
DE69230182T2 (de) | 2000-08-31 |
AU669148B2 (en) | 1996-05-30 |
AU3346793A (en) | 1993-07-19 |
EP0625056B1 (en) | 1999-10-20 |
RO111200B1 (ro) | 1996-07-30 |
NZ246576A (en) | 1997-07-27 |
NO942329L (sv) | 1994-08-17 |
BG98862A (bg) | 1995-05-31 |
HU217989B (hu) | 2000-05-28 |
DE69230182D1 (de) | 1999-11-25 |
CA2126087C (en) | 2001-02-13 |
FI942895A (sv) | 1994-08-18 |
FI942895A0 (sv) | 1994-06-16 |
GR3032451T3 (en) | 2000-05-31 |
NO942329D0 (no) | 1994-06-17 |
HUT68706A (en) | 1995-07-28 |
IT1254170B (it) | 1995-09-11 |
HU9401838D0 (en) | 1994-09-28 |
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Legal Events
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MA | Patent expired |