FI109019B - Menetelmä (S)-alfa-fenyyli-2-pyridiinietaaniamiinibentsoaatin valmistamiseksi - Google Patents

Menetelmä (S)-alfa-fenyyli-2-pyridiinietaaniamiinibentsoaatin valmistamiseksi Download PDF

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Publication number
FI109019B
FI109019B FI954646A FI954646A FI109019B FI 109019 B FI109019 B FI 109019B FI 954646 A FI954646 A FI 954646A FI 954646 A FI954646 A FI 954646A FI 109019 B FI109019 B FI 109019B
Authority
FI
Finland
Prior art keywords
phenyl
benzoate
compound
pyridine
ethanamine
Prior art date
Application number
FI954646A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI954646A (fi
FI954646A0 (fi
Inventor
Robert John Murray
Donald Mathisen
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB1993/000689 external-priority patent/WO1993020052A1/en
Application filed by Astra Ab filed Critical Astra Ab
Publication of FI954646A0 publication Critical patent/FI954646A0/fi
Publication of FI954646A publication Critical patent/FI954646A/fi
Application granted granted Critical
Publication of FI109019B publication Critical patent/FI109019B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI954646A 1993-04-01 1995-09-29 Menetelmä (S)-alfa-fenyyli-2-pyridiinietaaniamiinibentsoaatin valmistamiseksi FI109019B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/GB1993/000689 WO1993020052A1 (en) 1992-04-03 1993-04-01 Enantiomeric 1-phenyl-2-(2-pyridinyl)ethylamine for the treatment of neurodegenerative disorders
GB9300689 1993-04-01
GB9400716 1994-04-05
PCT/GB1994/000716 WO1994022832A1 (en) 1993-04-01 1994-04-05 (s)-alpha-phenyl-2-pyridineethanamine benzoate and its use as a medicament

Publications (3)

Publication Number Publication Date
FI954646A0 FI954646A0 (fi) 1995-09-29
FI954646A FI954646A (fi) 1995-11-29
FI109019B true FI109019B (fi) 2002-05-15

Family

ID=10728731

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954646A FI109019B (fi) 1993-04-01 1995-09-29 Menetelmä (S)-alfa-fenyyli-2-pyridiinietaaniamiinibentsoaatin valmistamiseksi

Country Status (13)

Country Link
EP (1) EP0691958B1 (ja)
JP (1) JP3023988B2 (ja)
AT (1) ATE156814T1 (ja)
AU (1) AU682350B2 (ja)
CA (1) CA2159480C (ja)
DE (1) DE69404975T2 (ja)
DK (1) DK0691958T3 (ja)
ES (1) ES2105679T3 (ja)
FI (1) FI109019B (ja)
GR (1) GR3025082T3 (ja)
NO (1) NO304648B1 (ja)
WO (1) WO1994022832A1 (ja)
ZA (1) ZA942140B (ja)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422191A (en) * 1965-01-21 1969-01-14 Synergistics Inc Compositions and methods for tranquilization employing salts of n-morpholine ethanol
GB9320273D0 (en) * 1993-04-01 1993-11-17 Fisons Corp Compound useful in therapy
EP0648489A1 (en) * 1988-08-12 1995-04-19 Fisons Corporation Arylalkylamides having neuroprotective properties
JP2514855B2 (ja) * 1990-08-08 1996-07-10 キッセイ薬品工業株式会社 光学活性なアラニンアニリド誘導体の酸付加塩
CA2133427C (en) * 1992-04-03 2003-06-10 Ronald Conrad Griffith Enantiomeric 1-phenyl-2-(2-pyridinyl) ethylamine for the treatment of neurodegenerative disorders

Also Published As

Publication number Publication date
ZA942140B (en) 1994-10-03
JP3023988B2 (ja) 2000-03-21
JPH08508475A (ja) 1996-09-10
DK0691958T3 (da) 1997-12-08
ES2105679T3 (es) 1997-10-16
NO953847L (no) 1995-11-22
DE69404975D1 (de) 1997-09-18
AU6433794A (en) 1994-10-24
EP0691958B1 (en) 1997-08-13
ATE156814T1 (de) 1997-08-15
NO953847D0 (no) 1995-09-28
DE69404975T2 (de) 1997-12-18
AU682350B2 (en) 1997-10-02
CA2159480C (en) 2005-01-25
CA2159480A1 (en) 1994-10-13
WO1994022832A1 (en) 1994-10-13
FI954646A (fi) 1995-11-29
NO304648B1 (no) 1999-01-25
FI954646A0 (fi) 1995-09-29
GR3025082T3 (en) 1998-01-30
EP0691958A1 (en) 1996-01-17

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Legal Events

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MA Patent expired