FI109019B - Förfarande för framställning av (S)-alfa-fenyl-2-pyridinetanaminbenzoat - Google Patents

Förfarande för framställning av (S)-alfa-fenyl-2-pyridinetanaminbenzoat Download PDF

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Publication number
FI109019B
FI109019B FI954646A FI954646A FI109019B FI 109019 B FI109019 B FI 109019B FI 954646 A FI954646 A FI 954646A FI 954646 A FI954646 A FI 954646A FI 109019 B FI109019 B FI 109019B
Authority
FI
Finland
Prior art keywords
phenyl
benzoate
compound
pyridine
ethanamine
Prior art date
Application number
FI954646A
Other languages
English (en)
Finnish (fi)
Other versions
FI954646A0 (sv
FI954646A (sv
Inventor
Robert John Murray
Donald Mathisen
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB1993/000689 external-priority patent/WO1993020052A1/en
Application filed by Astra Ab filed Critical Astra Ab
Publication of FI954646A0 publication Critical patent/FI954646A0/sv
Publication of FI954646A publication Critical patent/FI954646A/sv
Application granted granted Critical
Publication of FI109019B publication Critical patent/FI109019B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI954646A 1993-04-01 1995-09-29 Förfarande för framställning av (S)-alfa-fenyl-2-pyridinetanaminbenzoat FI109019B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9300689 1993-04-01
PCT/GB1993/000689 WO1993020052A1 (en) 1992-04-03 1993-04-01 Enantiomeric 1-phenyl-2-(2-pyridinyl)ethylamine for the treatment of neurodegenerative disorders
PCT/GB1994/000716 WO1994022832A1 (en) 1993-04-01 1994-04-05 (s)-alpha-phenyl-2-pyridineethanamine benzoate and its use as a medicament
GB9400716 1994-04-05

Publications (3)

Publication Number Publication Date
FI954646A0 FI954646A0 (sv) 1995-09-29
FI954646A FI954646A (sv) 1995-11-29
FI109019B true FI109019B (sv) 2002-05-15

Family

ID=10728731

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954646A FI109019B (sv) 1993-04-01 1995-09-29 Förfarande för framställning av (S)-alfa-fenyl-2-pyridinetanaminbenzoat

Country Status (13)

Country Link
EP (1) EP0691958B1 (sv)
JP (1) JP3023988B2 (sv)
AT (1) ATE156814T1 (sv)
AU (1) AU682350B2 (sv)
CA (1) CA2159480C (sv)
DE (1) DE69404975T2 (sv)
DK (1) DK0691958T3 (sv)
ES (1) ES2105679T3 (sv)
FI (1) FI109019B (sv)
GR (1) GR3025082T3 (sv)
NO (1) NO304648B1 (sv)
WO (1) WO1994022832A1 (sv)
ZA (1) ZA942140B (sv)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422191A (en) * 1965-01-21 1969-01-14 Synergistics Inc Compositions and methods for tranquilization employing salts of n-morpholine ethanol
GB9320273D0 (en) * 1993-04-01 1993-11-17 Fisons Corp Compound useful in therapy
ATE135206T1 (de) * 1988-08-12 1996-03-15 Astra Ab Arylalkylamine und -amide mit krampflösender und nervenschützender wirkung
JP2514855B2 (ja) * 1990-08-08 1996-07-10 キッセイ薬品工業株式会社 光学活性なアラニンアニリド誘導体の酸付加塩
DK0633879T3 (da) * 1992-04-03 1998-09-28 Astra Ab Enantiomert 1-phenyl-2(2-pyridinyl) ethylamin til behandling af neurodegenerative sygdomme

Also Published As

Publication number Publication date
DE69404975T2 (de) 1997-12-18
NO953847L (no) 1995-11-22
FI954646A0 (sv) 1995-09-29
NO304648B1 (no) 1999-01-25
NO953847D0 (no) 1995-09-28
EP0691958A1 (en) 1996-01-17
GR3025082T3 (en) 1998-01-30
AU6433794A (en) 1994-10-24
ZA942140B (en) 1994-10-03
DK0691958T3 (da) 1997-12-08
ATE156814T1 (de) 1997-08-15
JP3023988B2 (ja) 2000-03-21
CA2159480C (en) 2005-01-25
CA2159480A1 (en) 1994-10-13
EP0691958B1 (en) 1997-08-13
FI954646A (sv) 1995-11-29
ES2105679T3 (es) 1997-10-16
WO1994022832A1 (en) 1994-10-13
JPH08508475A (ja) 1996-09-10
AU682350B2 (en) 1997-10-02
DE69404975D1 (de) 1997-09-18

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Legal Events

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MA Patent expired