FI107432B - Användning av mikrokristallin kitosan - Google Patents

Användning av mikrokristallin kitosan Download PDF

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Publication number
FI107432B
FI107432B FI970499A FI970499A FI107432B FI 107432 B FI107432 B FI 107432B FI 970499 A FI970499 A FI 970499A FI 970499 A FI970499 A FI 970499A FI 107432 B FI107432 B FI 107432B
Authority
FI
Finland
Prior art keywords
chitosan
microcrystalline
microcrystalline chitosan
dispersion
weight
Prior art date
Application number
FI970499A
Other languages
English (en)
Finnish (fi)
Other versions
FI970499A (sv
FI970499A0 (fi
Inventor
Henryk Struszczyk
Olli Kivekaes
Elina Maekinen
Original Assignee
Novasso Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novasso Oy filed Critical Novasso Oy
Priority to FI970499A priority Critical patent/FI107432B/sv
Publication of FI970499A0 publication Critical patent/FI970499A0/fi
Priority to JP53381898A priority patent/JP2001512432A/ja
Priority to PCT/FI1998/000106 priority patent/WO1998034625A1/en
Priority to AU59890/98A priority patent/AU5989098A/en
Priority to EP98903026A priority patent/EP1014997A1/en
Priority to CA002280507A priority patent/CA2280507A1/en
Publication of FI970499A publication Critical patent/FI970499A/sv
Priority to US09/921,657 priority patent/US20030092673A1/en
Application granted granted Critical
Publication of FI107432B publication Critical patent/FI107432B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)

Claims (6)

12 Dt Λ 107432
1. Användning av mikrokristallin kitosan där man framställer ett farma-ceutiskt preparat eller näringsämne som skall givas oralt och är avsett 5 för minskning av absorption av lipider, varvid den mikrokristallina kitosanen är i pulverform, vars genomsnittliga partikelstorlek är under 100 pm och/eller i form av en geldispersion, vars genomsnittliga partikelstorlek är under 100 pm, varvid de kännetecknas av en genomsnittlig molekylvikt över lOOOOdalton, företrädesvis 50 000-10 700 000 dalton, och deacetyleringsgrad över 60%, företrädesvis 70- 95 %.
2. Användning enligt patentkravet 1, där det mikrokristallina kitosan-pulvret som är bildat genom spraytorkning i luft har vattenhällandevärde
15 WRV av minst 150 %, i synnerhet 200-300 %, och god direkt tabletter-barhet.
3. Användning enligt patentkravet 1, där det mikrokristallina kitosan-pulvret som är bildat genom köldtorkning har vattenhällandevärde WRV 20 av minst 200 %, i synnerhet 250-400 %.
4. Användning enligt patentkravet 1, där geldispersionen av mikro-kristallin kitosan innehällande över 0,1 vikt-% och företrädesvis 1-4 vikt-% mikrokristallin polymer har vattenhällandevärde WRV av minst 25 500 %, i synnerhet 800-5000 %.
5. Användning enligt patentkravet 1, när man framställer preparatet i form av pulver, geldispersion, tabletter och/eller kapslar som skall givas separat möjligtvis genom att förena den mikrokristallina kitosanen med 30 ett farmaceutiskt acceptabelt inert bärarmaterial.
6. Användning enligt patentkravet 1 genom att tillsätta den mikro- kristallina kitosanen tili ett näringsämne, säsom jogurt, smör eller ost. » 11 107432
FI970499A 1997-02-06 1997-02-06 Användning av mikrokristallin kitosan FI107432B (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FI970499A FI107432B (sv) 1997-02-06 1997-02-06 Användning av mikrokristallin kitosan
JP53381898A JP2001512432A (ja) 1997-02-06 1998-02-05 脂質およびコレステロールを減少させる物質および方法
PCT/FI1998/000106 WO1998034625A1 (en) 1997-02-06 1998-02-05 Substance and method for reduction of lipids and cholesterol
AU59890/98A AU5989098A (en) 1997-02-06 1998-02-05 Substance and method for reduction of lipids and cholesterol
EP98903026A EP1014997A1 (en) 1997-02-06 1998-02-05 Substance and method for reduction of lipids and cholesterol
CA002280507A CA2280507A1 (en) 1997-02-06 1998-02-05 Substance and method for reduction of lipids and cholesterol
US09/921,657 US20030092673A1 (en) 1997-02-06 2001-08-06 Substance and method for reduction of lipids and cholesterol

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI970499 1997-02-06
FI970499A FI107432B (sv) 1997-02-06 1997-02-06 Användning av mikrokristallin kitosan

Publications (3)

Publication Number Publication Date
FI970499A0 FI970499A0 (fi) 1997-02-06
FI970499A FI970499A (sv) 1998-08-07
FI107432B true FI107432B (sv) 2001-08-15

Family

ID=8548080

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970499A FI107432B (sv) 1997-02-06 1997-02-06 Användning av mikrokristallin kitosan

Country Status (6)

Country Link
EP (1) EP1014997A1 (sv)
JP (1) JP2001512432A (sv)
AU (1) AU5989098A (sv)
CA (1) CA2280507A1 (sv)
FI (1) FI107432B (sv)
WO (1) WO1998034625A1 (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9800912D0 (en) * 1998-01-17 1998-03-11 Danbiosyst Uk New composition
US6323189B1 (en) 1998-07-30 2001-11-27 E-Nutriceuticals, Inc. Chitosan-containing liquid compositions and methods for their preparation and use
FI982291A (sv) * 1998-10-23 2000-04-24 Novasso Oy Ämne för sänkning av halten av kolesterol samt lipider
FI113612B (sv) * 2001-04-25 2004-05-31 Moshe Meidan Funktionellt livsmedel och förfarande för dess framställning
KR20010085047A (ko) * 2001-07-25 2001-09-07 장태순 고분자 수용성 키토산의 고지방 식이에 의한 체 지방 증가억제 효과
KR20010085046A (ko) * 2001-07-25 2001-09-07 장태순 비만생쥐의 난소반응과 임신에서 고분자 수용성 키토산의효과
GB0302741D0 (en) * 2003-02-06 2003-03-12 Advanced Biopolymers As Use
DE10324548A1 (de) * 2003-05-28 2004-12-16 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Diätisches Lebensmittel bei einer gewichtskontrollierenden bzw. gewichtsreduzierenden Ernährung
US20060058261A1 (en) * 2004-09-15 2006-03-16 Andre Aube Chitin derivatives for hyperlipidemia
EP1960436A1 (en) * 2005-12-16 2008-08-27 Dnp Canada Inc. Chitin derivatives for hyperlipidemia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4223023A (en) * 1978-10-12 1980-09-16 Ivan Furda Nonabsorbable lipid binder
IT1207504B (it) * 1985-09-26 1989-05-25 Crinos Industria Farmaco Composizione moderatrice dell'appetito ed antigastrica.
FI83426C (sv) * 1989-06-30 1991-07-10 Firextra Oy Förfarande för kontinuerlig framställning av mikrokristallin kitosan
JP2667351B2 (ja) * 1992-03-24 1997-10-27 麒麟麦酒株式会社 食餌脂質消化吸収阻害剤および飲食品

Also Published As

Publication number Publication date
AU5989098A (en) 1998-08-26
CA2280507A1 (en) 1998-08-13
FI970499A (sv) 1998-08-07
FI970499A0 (fi) 1997-02-06
JP2001512432A (ja) 2001-08-21
WO1998034625A1 (en) 1998-08-13
EP1014997A1 (en) 2000-07-05

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