FI103116B1 - Menetelmä uusien, terapeuttisesti käyttökelpoisten, N-substituoitujen atsaheterosyklisten karboksyylihappojohdannaisten valmistamiseksi - Google Patents

Menetelmä uusien, terapeuttisesti käyttökelpoisten, N-substituoitujen atsaheterosyklisten karboksyylihappojohdannaisten valmistamiseksi

Info

Publication number
FI103116B1
FI103116B1 FI935064A FI935064A FI103116B1 FI 103116 B1 FI103116 B1 FI 103116B1 FI 935064 A FI935064 A FI 935064A FI 935064 A FI935064 A FI 935064A FI 103116 B1 FI103116 B1 FI 103116B1
Authority
FI
Finland
Prior art keywords
preparation
carboxylic acid
acid derivatives
therapeutically useful
novel therapeutically
Prior art date
Application number
FI935064A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI935064A (fi
FI935064A0 (fi
FI103116B (fi
Inventor
Knud Erik Andersen
Lars Jacob Stray Knutsen
Per Olav Soerensen
Behrend Friedrich Lundt
Jesper Lau
Hans Petersen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI935064A publication Critical patent/FI935064A/fi
Publication of FI935064A0 publication Critical patent/FI935064A0/fi
Application granted granted Critical
Publication of FI103116B publication Critical patent/FI103116B/fi
Publication of FI103116B1 publication Critical patent/FI103116B1/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI935064A 1991-05-17 1993-11-16 Menetelmä uusien, terapeuttisesti käyttökelpoisten, N-substituoitujen atsaheterosyklisten karboksyylihappojohdannaisten valmistamiseksi FI103116B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK93791 1991-05-17
DK91937A DK93791D0 (da) 1991-05-17 1991-05-17 Nye heterocykliske carboxylsyrer
DK9200155 1992-05-14
PCT/DK1992/000155 WO1992020658A1 (en) 1991-05-17 1992-05-14 Novel heterocyclic carboxylic acids

Publications (4)

Publication Number Publication Date
FI935064A FI935064A (fi) 1993-11-16
FI935064A0 FI935064A0 (fi) 1993-11-16
FI103116B FI103116B (fi) 1999-04-30
FI103116B1 true FI103116B1 (fi) 1999-04-30

Family

ID=8099201

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935064A FI103116B1 (fi) 1991-05-17 1993-11-16 Menetelmä uusien, terapeuttisesti käyttökelpoisten, N-substituoitujen atsaheterosyklisten karboksyylihappojohdannaisten valmistamiseksi

Country Status (16)

Country Link
US (1) US5348965A (no)
EP (1) EP0585314B1 (no)
JP (1) JPH06507616A (no)
AT (1) ATE143009T1 (no)
AU (1) AU665761B2 (no)
CA (1) CA2102811A1 (no)
DE (1) DE69213935T2 (no)
DK (2) DK93791D0 (no)
ES (1) ES2094357T3 (no)
FI (1) FI103116B1 (no)
GR (1) GR3021822T3 (no)
IL (1) IL101887A (no)
NO (1) NO300211B1 (no)
NZ (1) NZ242759A (no)
WO (1) WO1992020658A1 (no)
ZA (1) ZA923556B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK74493D0 (da) * 1993-06-23 1993-06-23 Novo Nordisk As Novel heterocyclic chemistry
DK74693D0 (da) * 1993-06-23 1993-06-23 Novo Nordisk As Novel heterocyclic chemistry
DK74393D0 (da) * 1993-06-23 1993-06-23 Novo Nordisk As Novel heterocyclic chemistry
IL112223A0 (en) * 1994-01-04 1995-03-30 Novo Nordisk As Pharmaceutical compositions for the treatment of neurological inflammatory conditions
US5698551A (en) * 1995-04-07 1997-12-16 Novo Nordisk A/S Heterocyclic compounds
US5962449A (en) 1995-04-07 1999-10-05 Novo Nordisk A/S Tricyclic compounds in treating hyperalgesic conditions and NIDDM
AU1138397A (en) * 1995-12-15 1997-07-14 Novo Nordisk A/S Novel method
WO1999000376A1 (en) * 1997-06-25 1999-01-07 Novo Nordisk A/S Novel heterocyclic compounds
IE970588A1 (en) 1997-08-01 2000-08-23 Elan Corp Plc Controlled release pharmaceutical compositions containing tiagabine
US6468996B1 (en) * 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
CN1382441A (zh) * 2002-05-21 2002-12-04 中国科学院上海生命科学研究院 γ-氨基丁酸转运蛋白抑制剂在制备镇痛药物中的应用
US7417040B2 (en) * 2004-03-01 2008-08-26 Bristol-Myers Squibb Company Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
US7378426B2 (en) * 2004-03-01 2008-05-27 Bristol-Myers Squibb Company Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL99690C (no) * 1956-11-15
BE560750A (no) * 1957-07-26
CH368178A (de) * 1958-09-10 1963-03-31 Geigy Ag J R Verfahren zur Herstellung von neuen basisch substituierten heterocyclischen Verbindungen
DK704488D0 (da) * 1988-12-19 1988-12-19 Novo Industri As Nye n-substituerede azaheterocykliske carboxylsyrer
FI864246A (fi) * 1985-11-08 1987-05-09 Warner Lambert Co N-substituerade 3-piperidin- eller 3-pyridinkarboxylsyror samt deras derivat.
US4910312A (en) * 1985-11-08 1990-03-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
DK270488D0 (da) * 1988-05-18 1988-05-18 Novo Industri As Hidtil ukendte o-substituerede ketoximer

Also Published As

Publication number Publication date
EP0585314B1 (en) 1996-09-18
NO934159L (no) 1993-11-17
NO300211B1 (no) 1997-04-28
JPH06507616A (ja) 1994-09-01
DK93791D0 (da) 1991-05-17
DK0585314T3 (no) 1997-05-05
FI935064A (fi) 1993-11-16
FI935064A0 (fi) 1993-11-16
GR3021822T3 (en) 1997-02-28
NZ242759A (en) 1995-03-28
AU1783792A (en) 1992-12-30
ATE143009T1 (de) 1996-10-15
EP0585314A1 (en) 1994-03-09
DE69213935T2 (de) 1997-03-27
US5348965A (en) 1994-09-20
FI103116B (fi) 1999-04-30
DE69213935D1 (en) 1996-10-24
AU665761B2 (en) 1996-01-18
ES2094357T3 (es) 1997-01-16
IL101887A0 (en) 1992-12-30
WO1992020658A1 (en) 1992-11-26
ZA923556B (en) 1993-01-27
CA2102811A1 (en) 1992-11-26
NO934159D0 (no) 1993-11-17
IL101887A (en) 1996-10-16

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