FI102902B1 - Förfarande för framställning av terapeutiskt användbara 14 ,17 -tvärbundna estratriener - Google Patents

Förfarande för framställning av terapeutiskt användbara 14 ,17 -tvärbundna estratriener

Info

Publication number
FI102902B1
FI102902B1 FI920843A FI920843A FI102902B1 FI 102902 B1 FI102902 B1 FI 102902B1 FI 920843 A FI920843 A FI 920843A FI 920843 A FI920843 A FI 920843A FI 102902 B1 FI102902 B1 FI 102902B1
Authority
FI
Finland
Prior art keywords
14alpha
17alpha
oestratriene
16alpha
17beta
Prior art date
Application number
FI920843A
Other languages
English (en)
Finnish (fi)
Other versions
FI920843A0 (fi
FI102902B (sv
Inventor
Gerald Kirsch
Guenter Neef
Henry Laurent
Rudolf Wiechert
James R Bull
Peter Esperling
Walter Elger
Sybille Beier
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3939894A external-priority patent/DE3939894A1/de
Priority claimed from DE3939893A external-priority patent/DE3939893A1/de
Priority claimed from DE4033871A external-priority patent/DE4033871A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI920843A0 publication Critical patent/FI920843A0/fi
Application granted granted Critical
Publication of FI102902B publication Critical patent/FI102902B/sv
Publication of FI102902B1 publication Critical patent/FI102902B1/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Fats And Perfumes (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicinal Preparation (AREA)
FI920843A 1989-11-29 1992-02-26 Förfarande för framställning av terapeutiskt användbara 14 ,17 -tvärbundna estratriener FI102902B1 (sv)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE3939894A DE3939894A1 (de) 1989-11-29 1989-11-29 14(alpha),17(alpha)-ethano-16(alpha)-hydroxy-estratriene
DE3939893A DE3939893A1 (de) 1989-11-29 1989-11-29 14(alpha),17(alpha)-etha(e)no-16ss-hydroxy-estratriene
DE3939894 1989-11-29
DE3939893 1989-11-29
DE4033871A DE4033871A1 (de) 1990-10-22 1990-10-22 Verfahren zur herstellung von 14(alpha), 17(alpha)-etheno- und ethano-estriolen
DE4033871 1990-10-22
PCT/DE1990/000924 WO1991008219A1 (de) 1989-11-29 1990-11-29 14α,17α-ÜBERBRÜCKTE 16-HYDROXYESTRATRIENE
DE9000924 1990-11-29

Publications (3)

Publication Number Publication Date
FI920843A0 FI920843A0 (fi) 1992-02-26
FI102902B FI102902B (sv) 1999-03-15
FI102902B1 true FI102902B1 (sv) 1999-03-15

Family

ID=27200525

Family Applications (1)

Application Number Title Priority Date Filing Date
FI920843A FI102902B1 (sv) 1989-11-29 1992-02-26 Förfarande för framställning av terapeutiskt användbara 14 ,17 -tvärbundna estratriener

Country Status (21)

Country Link
US (1) US5529993A (sv)
EP (1) EP0430386B1 (sv)
JP (1) JP2996723B2 (sv)
KR (1) KR100203003B1 (sv)
CN (2) CN1031061C (sv)
AT (1) ATE122053T1 (sv)
AU (1) AU649239B2 (sv)
CA (1) CA2069880A1 (sv)
CZ (1) CZ286259B6 (sv)
DE (1) DE59009011D1 (sv)
DK (1) DK0430386T3 (sv)
ES (1) ES2074531T3 (sv)
FI (1) FI102902B1 (sv)
HU (1) HU220217B (sv)
IE (1) IE67321B1 (sv)
IL (1) IL96501A (sv)
NO (1) NO301232B1 (sv)
PH (1) PH31668A (sv)
PT (1) PT96035B (sv)
RU (1) RU2087479C1 (sv)
WO (1) WO1991008219A1 (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132182A1 (de) * 1991-09-24 1993-03-25 Schering Ag 11(beta)-substituierte 14, 17-ethanoestratriene, verfahren zur herstellung dieser verbindungen, sowie ihre verwendung zur herstellung von arzneimitteln
DE4222316A1 (de) * 1992-07-03 1994-01-05 Schering Ag Verfahren zur Herstellung von Etheno- und Ethano-16â,17µ-Steroiddiolen und deren Derivaten
DE4447714C2 (de) * 1994-08-09 1998-02-05 Jenapharm Gmbh Verwendung von Estra-1,3,5(10)-trien-Derivaten zur Hormonsubstitutions-Therapie
DE4429397C2 (de) * 1994-08-09 2003-11-20 Jenapharm Gmbh Estra-1,3,5(10)-trien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
CN113999276B (zh) * 2020-07-28 2023-08-15 威智医药股份有限公司 一种去乙酰毛花苷中间体的提纯方法以及制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE808679C (de) * 1948-10-19 1951-07-19 Hansen Neuerburg & Co Mit Leitflaechen versehene Propelleranordnung fuer Schiffe
DE3628189A1 (de) * 1986-08-20 1988-02-25 Schering Ag Oestrogen wirksame mittel und 14,17ss-ethano-14ss-estratriene
DE3808679A1 (de) * 1988-03-11 1989-09-21 Schering Ag Verfahren zur herstellung von 14,17(alpha)-etheno-1,3,5(10)-estratrienen

Also Published As

Publication number Publication date
JPH05503080A (ja) 1993-05-27
DK0430386T3 (da) 1995-09-04
ES2074531T3 (es) 1995-09-16
AU649239B2 (en) 1994-05-19
DE59009011D1 (de) 1995-06-08
ATE122053T1 (de) 1995-05-15
EP0430386A1 (de) 1991-06-05
EP0430386B1 (de) 1995-05-03
NO921910D0 (no) 1992-05-14
CN1057769C (zh) 2000-10-25
CZ286259B6 (cs) 2000-02-16
FI920843A0 (fi) 1992-02-26
JP2996723B2 (ja) 2000-01-11
IL96501A (en) 1997-07-13
HU220217B (hu) 2001-11-28
NO921910L (no) 1992-05-14
HUT67420A (en) 1995-04-28
WO1991008219A1 (de) 1991-06-13
PT96035A (pt) 1991-09-13
KR100203003B1 (ko) 1999-06-15
NO301232B1 (no) 1997-09-29
CN1052677A (zh) 1991-07-03
KR927003620A (ko) 1992-12-18
RU2087479C1 (ru) 1997-08-20
IE904316A1 (en) 1991-06-05
AU6884191A (en) 1991-06-26
HU9201805D0 (en) 1992-08-28
CZ594390A3 (cs) 1999-11-17
US5529993A (en) 1996-06-25
PH31668A (en) 1999-01-18
IL96501A0 (en) 1991-08-16
CA2069880A1 (en) 1991-05-30
CN1117050A (zh) 1996-02-21
PT96035B (pt) 1998-01-30
CN1031061C (zh) 1996-02-21
FI102902B (sv) 1999-03-15
IE67321B1 (en) 1996-03-20

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