FI101541B1 - Menetelmä trisakkaridiyksikön sisältävien terapeuttisesti käyttökelpoisten hiilihydraattijohdannaisten valmistamiseksi - Google Patents

Menetelmä trisakkaridiyksikön sisältävien terapeuttisesti käyttökelpoisten hiilihydraattijohdannaisten valmistamiseksi

Info

Publication number
FI101541B1
FI101541B1 FI911942A FI911942A FI101541B1 FI 101541 B1 FI101541 B1 FI 101541B1 FI 911942 A FI911942 A FI 911942A FI 911942 A FI911942 A FI 911942A FI 101541 B1 FI101541 B1 FI 101541B1
Authority
FI
Finland
Prior art keywords
preparation
therapeutically useful
derivatives containing
carbohydrate derivatives
trisaccharide unit
Prior art date
Application number
FI911942A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI911942A0 (fi
FI101541B (fi
FI911942A (fi
Inventor
Boeckel Constant Adriaan A Van
Maurice Petitou
Original Assignee
Akzo Nv
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv, Sanofi Sa filed Critical Akzo Nv
Publication of FI911942A0 publication Critical patent/FI911942A0/fi
Publication of FI911942A publication Critical patent/FI911942A/fi
Application granted granted Critical
Publication of FI101541B1 publication Critical patent/FI101541B1/fi
Publication of FI101541B publication Critical patent/FI101541B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FI911942A 1990-04-23 1991-04-22 Menetelmä trisakkaridiyksikön sisältävien terapeuttisesti käyttökelpoi sten hiilihydraattijohdannaisten valmistamiseksi FI101541B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90201006 1990-04-23
EP90201006 1990-08-23

Publications (4)

Publication Number Publication Date
FI911942A0 FI911942A0 (fi) 1991-04-22
FI911942A FI911942A (fi) 1991-10-24
FI101541B1 true FI101541B1 (fi) 1998-07-15
FI101541B FI101541B (fi) 1998-07-15

Family

ID=8205000

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911942A FI101541B (fi) 1990-04-23 1991-04-22 Menetelmä trisakkaridiyksikön sisältävien terapeuttisesti käyttökelpoi sten hiilihydraattijohdannaisten valmistamiseksi

Country Status (16)

Country Link
EP (1) EP0454220B1 (pt)
KR (1) KR0185991B1 (pt)
AU (1) AU644429B2 (pt)
BR (1) BR1100979A (pt)
CA (1) CA2040905C (pt)
DE (1) DE69100275T2 (pt)
DK (1) DK0454220T3 (pt)
ES (1) ES2060284T3 (pt)
FI (1) FI101541B (pt)
HK (1) HK1002319A1 (pt)
HU (2) HU215152B (pt)
IE (1) IE64378B1 (pt)
IL (1) IL97904A (pt)
NZ (1) NZ237909A (pt)
PT (1) PT97437B (pt)
ZA (1) ZA912951B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
US5696100A (en) * 1992-12-22 1997-12-09 Glycomed Incorporated Method for controlling O-desulfation of heparin and compositions produced thereby
DE69418322D1 (de) * 1993-03-01 1999-06-10 Glycan Pharm Inc Analoge für spezifische oligosaccharid-protein-wechselwirkungen und ihre verwendungen
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
NZ264340A (en) * 1993-09-01 1995-04-27 Akzo Nobel Nv Bisconjugate comprising two saccharides and a spacer, use in pharmaceutical compositions
US5498775A (en) * 1994-11-07 1996-03-12 American Home Products Corporation Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
US5565432A (en) * 1994-11-07 1996-10-15 American Home Products Corporation Smooth muscle cell proliferation inhibitors
IL115745A (en) * 1994-11-07 2000-11-21 American Home Prod Acylated benzylglycosides and pharmaceutical compositions containing them
IL120722A (en) * 1996-05-08 1999-07-14 Akzo Nobel Nv Polysulfated tetrasaccharide derivatives and pharmaceutical compositions containing them
IL126893A (en) * 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en) 1998-11-24 2002-09-17 Wyeth Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en) 1998-11-24 2001-09-18 American Home Products Corp. Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US7081448B2 (en) 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en) 1998-11-24 2001-02-13 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
SE9904483D0 (sv) * 1999-12-08 1999-12-08 Astra Ab New use
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
WO2009155108A1 (en) 2008-05-30 2009-12-23 Momenta Pharmaceuticals, Inc. Saccharide structures and methods of making and using such structures
US9873712B2 (en) 2014-10-03 2018-01-23 Amphastar Pharmaceuticals, Inc. Method of purifying idraparinux sodium

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
DE3734815A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
EP0333243A3 (en) * 1988-03-10 1989-09-27 Akzo N.V. Sulphated k5 antigen and sulphated k5 antigen fragments
JPH0296588A (ja) * 1988-09-29 1990-04-09 Rikagaku Kenkyusho 硫酸化オリゴ糖及びその関連物質

Also Published As

Publication number Publication date
ZA912951B (en) 1992-01-29
CA2040905A1 (en) 1991-10-24
FI911942A0 (fi) 1991-04-22
KR0185991B1 (ko) 1999-04-01
DE69100275D1 (de) 1993-09-23
EP0454220B1 (en) 1993-08-18
EP0454220A1 (en) 1991-10-30
NZ237909A (en) 1993-03-26
AU7525591A (en) 1991-10-24
KR910018398A (ko) 1991-11-30
DK0454220T3 (da) 1993-11-22
HUT57223A (en) 1991-11-28
CA2040905C (en) 2001-11-20
PT97437B (pt) 1998-08-31
BR1100979A (pt) 1999-12-07
DE69100275T2 (de) 1993-12-02
AU644429B2 (en) 1993-12-09
FI101541B (fi) 1998-07-15
PT97437A (pt) 1992-01-31
ES2060284T3 (es) 1994-11-16
IL97904A (en) 1995-07-31
HU911346D0 (en) 1991-10-28
IE64378B1 (en) 1995-07-26
IL97904A0 (en) 1992-06-21
FI911942A (fi) 1991-10-24
HU215152B (hu) 2000-11-28
IE911277A1 (en) 1991-10-23
HU211506A9 (en) 1995-11-28
HK1002319A1 (en) 1998-08-14

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Owner name: SANOFI-AVENTIS