ES8801224A1 - Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazazacicloalcadieno - Google Patents

Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazazacicloalcadieno

Info

Publication number
ES8801224A1
ES8801224A1 ES555533A ES555533A ES8801224A1 ES 8801224 A1 ES8801224 A1 ES 8801224A1 ES 555533 A ES555533 A ES 555533A ES 555533 A ES555533 A ES 555533A ES 8801224 A1 ES8801224 A1 ES 8801224A1
Authority
ES
Spain
Prior art keywords
denotes
mercapto
etherified
radicals
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555533A
Other languages
English (en)
Other versions
ES555533A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES555533A0 publication Critical patent/ES555533A0/es
Publication of ES8801224A1 publication Critical patent/ES8801224A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE 3-MERCAPTO-1,2,4-TRIAZACICLOALCADIENO. CONSISTE EN CALENTAR A UN COMPUESTO DE FORMULA (II), ENTRE 40 Y 200JC, EN PRESENCIA DE UN ACIDO SULFONICO ORGANICO Y EN BENCENO, PARA ELIMINAR AGUA Y OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: R1 Y R2 INDEPENDIENTES GRUPOS ARILO SUSTITUIDOS POR HIDROCARBURO ALIFATICOS, HIDROXI LIBRE Y OTROS; R3, UN RESTO HIDROCARBURO ALIFATICO SUSTITUIDO POR UN GRUPO CARBOXI; Y2, H; Y3 E Y4, UN ENLACE ADICIONAL; Y N, 0, 1 O 2. SE UTILIZAN COMO ANTIINFLAMATORIOS.
ES555533A 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazazacicloalcadieno Expired ES8801224A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH133084 1984-03-16

Publications (2)

Publication Number Publication Date
ES555533A0 ES555533A0 (es) 1987-12-16
ES8801224A1 true ES8801224A1 (es) 1987-12-16

Family

ID=4207944

Family Applications (7)

Application Number Title Priority Date Filing Date
ES541325A Expired ES8702377A1 (es) 1984-03-16 1985-03-15 Procedimiento para la obtencion de nuevos derivados de 3- mercapto-1,2,4-triazacicloalcadieno
ES555537A Expired ES8800914A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno
ES555536A Expired ES8801226A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno.
ES555533A Expired ES8801224A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazazacicloalcadieno
ES555534A Expired ES8800913A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno
ES555535A Expired ES8801225A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2-,4-triazacicloalcadieno.
ES557461A Expired ES8801804A1 (es) 1984-03-16 1987-03-18 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES541325A Expired ES8702377A1 (es) 1984-03-16 1985-03-15 Procedimiento para la obtencion de nuevos derivados de 3- mercapto-1,2,4-triazacicloalcadieno
ES555537A Expired ES8800914A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno
ES555536A Expired ES8801226A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES555534A Expired ES8800913A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno
ES555535A Expired ES8801225A1 (es) 1984-03-16 1986-05-30 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2-,4-triazacicloalcadieno.
ES557461A Expired ES8801804A1 (es) 1984-03-16 1987-03-18 Procedimiento para la obtencion de nuevos derivados de 3-mercapto-1,2,4-triazacicloalcadieno

Country Status (15)

Country Link
EP (1) EP0157259A1 (es)
JP (1) JPS60209574A (es)
KR (1) KR850006387A (es)
AU (1) AU4004085A (es)
DD (1) DD234006A5 (es)
DK (1) DK119685A (es)
ES (7) ES8702377A1 (es)
FI (1) FI850995L (es)
GR (1) GR850652B (es)
HU (1) HUT37408A (es)
IL (1) IL74596A0 (es)
NO (1) NO851036L (es)
PH (1) PH21777A (es)
PT (1) PT80105B (es)
ZA (1) ZA851952B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931083A (en) * 1985-11-12 1990-06-05 Eli Lilly And Company Plant growth regulating triazoles
PT83711B (en) * 1985-11-12 1988-12-06 Lilly Co Eli Process for preparing plant growth regulating triazoles
AUPR878201A0 (en) 2001-11-09 2001-12-06 Fujisawa Pharmaceutical Co., Ltd. New compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2558951A1 (de) * 1974-12-28 1976-07-08 Canon Kk Durch erwaermung entwickelbares, lichtempfindliches material
DK16778A (da) * 1977-02-09 1978-08-10 Du Pont Imidazolderivater deres anvendelser og fremstilling
DE2856909A1 (de) * 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
ES555533A0 (es) 1987-12-16
ES557461A0 (es) 1988-02-16
DK119685D0 (da) 1985-03-15
ES555537A0 (es) 1987-12-01
EP0157259A1 (de) 1985-10-09
ES8801226A1 (es) 1988-01-01
PT80105B (en) 1987-03-24
JPS60209574A (ja) 1985-10-22
NO851036L (no) 1985-09-17
ES8702377A1 (es) 1987-01-01
DK119685A (da) 1985-09-17
AU4004085A (en) 1985-09-19
ES8800914A1 (es) 1987-12-01
IL74596A0 (en) 1985-06-30
FI850995L (fi) 1985-09-17
FI850995A0 (fi) 1985-03-13
KR850006387A (ko) 1985-10-05
HUT37408A (en) 1985-12-28
ZA851952B (en) 1985-11-27
ES8801225A1 (es) 1988-01-01
PT80105A (en) 1985-04-01
ES541325A0 (es) 1987-01-01
ES555534A0 (es) 1987-12-01
ES8801804A1 (es) 1988-02-16
GR850652B (es) 1985-07-16
DD234006A5 (de) 1986-03-19
ES8800913A1 (es) 1987-12-01
PH21777A (en) 1988-02-24
ES555536A0 (es) 1988-01-01
ES555535A0 (es) 1988-01-01

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