ES8306099A1 - Un procedimiento para la preparacion de derivados de acido 2-(2-cianoetil)-2-benzoilamino-alcanoicos. - Google Patents

Un procedimiento para la preparacion de derivados de acido 2-(2-cianoetil)-2-benzoilamino-alcanoicos.

Info

Publication number
ES8306099A1
ES8306099A1 ES500585A ES500585A ES8306099A1 ES 8306099 A1 ES8306099 A1 ES 8306099A1 ES 500585 A ES500585 A ES 500585A ES 500585 A ES500585 A ES 500585A ES 8306099 A1 ES8306099 A1 ES 8306099A1
Authority
ES
Spain
Prior art keywords
group
alkyl
amino
substituted
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES500585A
Other languages
English (en)
Other versions
ES500585A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES500585A0 publication Critical patent/ES500585A0/es
Publication of ES8306099A1 publication Critical patent/ES8306099A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL ACIDO 2-(2-CIANOETIL)-2-BENZOILAMINO-ALCANOICOS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R Y R SON HIDROGENO O ALQUILO; R , R Y A PUEDEN SER VARIOS TIPOS DE RADICALES; Y N VALE 1-5. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE HAL ES HALOGENO, M ES ALQUILO Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA ENTRE -20 C Y 100 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD INMUNORREGULADORA Y ANTITUMORAL.
ES500585A 1980-03-22 1981-03-20 Un procedimiento para la preparacion de derivados de acido 2-(2-cianoetil)-2-benzoilamino-alcanoicos. Expired ES8306099A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3656280A JPS56147753A (en) 1980-03-22 1980-03-22 Amino acid derivative

Publications (2)

Publication Number Publication Date
ES500585A0 ES500585A0 (es) 1983-05-01
ES8306099A1 true ES8306099A1 (es) 1983-05-01

Family

ID=12473192

Family Applications (1)

Application Number Title Priority Date Filing Date
ES500585A Expired ES8306099A1 (es) 1980-03-22 1981-03-20 Un procedimiento para la preparacion de derivados de acido 2-(2-cianoetil)-2-benzoilamino-alcanoicos.

Country Status (11)

Country Link
US (1) US4545942A (es)
JP (1) JPS56147753A (es)
BE (1) BE888057A (es)
CA (1) CA1165328A (es)
CH (1) CH651820A5 (es)
DE (1) DE3111025A1 (es)
ES (1) ES8306099A1 (es)
FR (1) FR2478629A1 (es)
GB (1) GB2072173B (es)
IT (1) IT1172237B (es)
NL (1) NL8101439A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3416120A1 (de) * 1984-04-30 1985-10-31 Henkel KGaA, 4000 Düsseldorf Benzoylalanine und ihre verwendung als korrosionsinhibitoren fuer waessrige systeme
CN104803876B (zh) * 2014-01-28 2018-02-02 杭州民生药业有限公司 一种o‑肉桂酰‑(4‑三氟甲基)水杨酰胺类化合物及其应用
CN104800228B (zh) * 2014-01-28 2019-04-12 杭州民生药物研究院有限公司 一种o-苯甲酰-(4-三氟甲基)水杨酰胺类化合物在制备治疗肠癌药物中的应用
CN104800225B (zh) * 2014-01-28 2018-12-18 杭州民生药物研究院有限公司 一种o-苯乙酰-(4-三氟甲基)水杨酰胺类化合物在制备治疗肺癌药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125583A (en) * 1964-03-17 Hjnc oxchaxohxchc o oh
US2553737A (en) * 1945-06-16 1951-05-22 Winthrop Stearns Inc Lower alkyl (beta-cyanoalkyl)-(lower acyl) aminomalonates
US2847451A (en) * 1954-10-01 1958-08-12 Nat Distillers Chem Corp Growth accelerator
US2891053A (en) * 1955-12-20 1959-06-16 Bayer Ag Therapeutically valuable calcium salts
JPS5569552A (en) * 1978-11-20 1980-05-26 Dai Ichi Pure Chem Co Ltd Optically active alpha-acylamino-gamma-cyanobutyric acid ester

Also Published As

Publication number Publication date
IT1172237B (it) 1987-06-18
DE3111025C2 (es) 1989-12-07
FR2478629A1 (fr) 1981-09-25
ES500585A0 (es) 1983-05-01
IT8167391A0 (it) 1981-03-20
CA1165328A (en) 1984-04-10
GB2072173A (en) 1981-09-30
US4545942A (en) 1985-10-08
DE3111025A1 (de) 1982-01-14
JPS6332780B2 (es) 1988-07-01
FR2478629B1 (es) 1983-06-24
JPS56147753A (en) 1981-11-16
CH651820A5 (de) 1985-10-15
GB2072173B (en) 1984-07-25
NL8101439A (nl) 1981-10-16
BE888057A (fr) 1981-09-21

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519