ES8706640A1 - Procedimiento para preparar una antra (1,9-cd)priazol-6-(2h)-ona sustituida - Google Patents

Procedimiento para preparar una antra (1,9-cd)priazol-6-(2h)-ona sustituida

Info

Publication number
ES8706640A1
ES8706640A1 ES554394A ES554394A ES8706640A1 ES 8706640 A1 ES8706640 A1 ES 8706640A1 ES 554394 A ES554394 A ES 554394A ES 554394 A ES554394 A ES 554394A ES 8706640 A1 ES8706640 A1 ES 8706640A1
Authority
ES
Spain
Prior art keywords
pyrazol
ones
preparing substituted
anthra
substituted anthra
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554394A
Other languages
English (en)
Other versions
ES554394A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES554394A0 publication Critical patent/ES554394A0/es
Publication of ES8706640A1 publication Critical patent/ES8706640A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA ANTRA (1,9-CD)PIRAZOL-6-(2H)-ONA SUSTITUIDA. COMPRENDE: A) HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON UNA HIDRAZINA DE FORMULA (H2NNHDNHR''), PARA OBTENER EN COMPUESTO DE FORMULA (III); B) TRATAR A (III) CON HALURO DE BENCILO, EN PRESENCIA DE CARBONATO ALCALINO, PARA FORMAR UN COMPUESTO DE FORMULA (IV); C) COMBINAR A (IV) CON UNA DIAMINA DE FORMULA (HRND''NR4R5), PARA PRODUCIR UN COMPUESTO DE FORMULA (I). SIENDO: A, Q'' Y Q'''', H, BENCILOXI Y OTROS; D Y D'', ALQUILENO RECTO DE C 2 A 8; R, H O ALQUILO DE C 1 A 6; R'' ALQUILO DE C 2 A 8; R4, H; Y R5, BENCILO. SE UTILIZAN COMO ANTIFUNGALES. *FORMULA*
ES554394A 1985-04-26 1986-04-25 Procedimiento para preparar una antra (1,9-cd)priazol-6-(2h)-ona sustituida Expired ES8706640A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/727,637 US4608439A (en) 1985-04-26 1985-04-26 Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones

Publications (2)

Publication Number Publication Date
ES554394A0 ES554394A0 (es) 1987-07-01
ES8706640A1 true ES8706640A1 (es) 1987-07-01

Family

ID=24923408

Family Applications (1)

Application Number Title Priority Date Filing Date
ES554394A Expired ES8706640A1 (es) 1985-04-26 1986-04-25 Procedimiento para preparar una antra (1,9-cd)priazol-6-(2h)-ona sustituida

Country Status (10)

Country Link
US (1) US4608439A (es)
EP (1) EP0203697B1 (es)
JP (1) JPH0730033B2 (es)
AT (1) ATE53578T1 (es)
AU (1) AU578526B2 (es)
CA (1) CA1261828A (es)
DE (1) DE3671893D1 (es)
DK (1) DK165446C (es)
ES (1) ES8706640A1 (es)
ZA (1) ZA862392B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672129A (en) * 1986-05-05 1987-06-09 Warner-Lambert Company Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones
US5393886A (en) * 1993-05-05 1995-02-28 The Du Pont Merck Pharmaceutical Company Intermediates for the synthesis of anthrapyrazolone anticancer agents
DE19714799C2 (de) * 1997-04-10 2001-08-02 Kristian Dicke Vorrichtung zum Lagern von Wareneinheiten
AU6508899A (en) 1998-10-13 2000-05-01 Du Pont Pharmaceuticals Company Selective eradication of virally-infected cells by combined use of a cytotoxic agent and an antiviral agent
CN102603785B (zh) * 2012-02-27 2014-08-13 上海大学 萘并或蒽并吡唑衍生物及其合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB470475A (en) * 1936-02-14 1937-08-16 Of Chemical Industry Soc Manufacture of dyestuffs and intermediate products
US2518150A (en) * 1946-02-01 1950-08-08 Ciba Ltd Vat dyestuffs
IL69211A (en) * 1982-07-23 1987-01-30 Warner Lambert Co Substituted anthra(1,9-cd)pyrazol-6(2h)-ones,their preparation and pharmaceutical compositions containing them
US4556654A (en) * 1983-06-28 1985-12-03 Warner-Lambert Company Antimicrobial substituted anthra[1,9-cd]pyrazol-6(2H)-ones

Also Published As

Publication number Publication date
DK186186A (da) 1986-10-27
US4608439A (en) 1986-08-26
ZA862392B (en) 1987-11-25
CA1261828A (en) 1989-09-26
ATE53578T1 (de) 1990-06-15
DK165446C (da) 1993-04-13
DK165446B (da) 1992-11-30
AU5575186A (en) 1986-10-30
EP0203697A1 (en) 1986-12-03
DE3671893D1 (de) 1990-07-19
ES554394A0 (es) 1987-07-01
JPH0730033B2 (ja) 1995-04-05
DK186186D0 (da) 1986-04-23
JPS61254568A (ja) 1986-11-12
AU578526B2 (en) 1988-10-27
EP0203697B1 (en) 1990-06-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060424