ES8705908A1 - Procedimiento para producir derivados quitosanicos en forma de complejos coordinados con iones ferrosos - Google Patents

Procedimiento para producir derivados quitosanicos en forma de complejos coordinados con iones ferrosos

Info

Publication number
ES8705908A1
ES8705908A1 ES552951A ES552951A ES8705908A1 ES 8705908 A1 ES8705908 A1 ES 8705908A1 ES 552951 A ES552951 A ES 552951A ES 552951 A ES552951 A ES 552951A ES 8705908 A1 ES8705908 A1 ES 8705908A1
Authority
ES
Spain
Prior art keywords
chitosan derivatives
ferrous ions
coordinated
coordinated complexes
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552951A
Other languages
English (en)
Other versions
ES552951A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmhispania SA
Original Assignee
Farmhispania SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmhispania SA filed Critical Farmhispania SA
Publication of ES552951A0 publication Critical patent/ES552951A0/es
Publication of ES8705908A1 publication Critical patent/ES8705908A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

PROCEDIMIENTO PARA PRODUCIR DERIVADOS SOLUBLES DE QUITOSANO. COMPRENDE: A) DISOLVER AL QUITOSANO CON ACIDO ACETICO DILUIDO; B) TRATAR A LA DISOLUCION DE A) CON UNA SOLUCION ACUOSA DE SULFATO FERROSO DE PH ENTRE 2 Y 7, A UNA TEMPERATURA DE 10 A 25JC Y DURANTE 2 A 16 HORAS, PARA PRECIPITAR UN COMPLEJO FERROSO EN SOLUCION; C) FILTRAR LA MEZCLA DE B); D) LAVAR CON AGUA/METANOL AL PRECIPITADO SEPARADO EN C); E) SECAR AL PRECIPITADO ENTRE 40 Y 50JC Y CON VACIO; F) SULFATAR AL PRECIPITADO CON UNA MEZCLA DE TRIOXIDO DE AZUFRE/PIRIDINA; G) TRATAR AL PRECIPITADO SULFATADO CON UNA BASE ORGANICA; H) DIALIZAR LA MEZCLA DE G) CON AGUA, PARA OBTENER DERIVADOS QUITOSANICOS EN FORMA DE COMPLEJOS COORDENADOS CON IONES FERROSOS QUE TIENEN QUITOSANOS 6-0-SULFATO. SE UTILIZA PARA TRATAR ENFERMEDADES GASTROINTESTINALES.
ES552951A 1985-03-14 1986-03-13 Procedimiento para producir derivados quitosanicos en forma de complejos coordinados con iones ferrosos Expired ES8705908A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19916/85A IT1184161B (it) 1985-03-14 1985-03-14 Derivati del chitosano costituiti da complessi di coordinazione con ioni ferrosi

Publications (2)

Publication Number Publication Date
ES552951A0 ES552951A0 (es) 1987-05-16
ES8705908A1 true ES8705908A1 (es) 1987-05-16

Family

ID=11162310

Family Applications (1)

Application Number Title Priority Date Filing Date
ES552951A Expired ES8705908A1 (es) 1985-03-14 1986-03-13 Procedimiento para producir derivados quitosanicos en forma de complejos coordinados con iones ferrosos

Country Status (4)

Country Link
US (1) US4810695A (es)
EP (1) EP0194497A3 (es)
ES (1) ES8705908A1 (es)
IT (1) IT1184161B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01238161A (ja) * 1988-03-18 1989-09-22 Fujitsu Ltd 半導体装置及びその製造方法
IT1229167B (it) * 1989-04-10 1991-07-22 Texcontor Ets Complessi del ferro o di altri metalli con derivati solfonati del chitosano
JPH04117401A (ja) * 1990-09-07 1992-04-17 Dic Hercules Chem Inc スルフォン化キトサンの製造法
US5912000A (en) * 1994-09-23 1999-06-15 Zonagen, Inc. Chitosan induced immunopotentiation
WO1997047323A2 (en) * 1996-06-11 1997-12-18 Zonagen, Inc. Chitosan drug delivery system
US5906978A (en) * 1996-08-14 1999-05-25 Hemocleanse, Inc. Method for iron delivery to a patient by transfer from dialysate
IT1303738B1 (it) * 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
US20050281891A1 (en) * 2004-06-03 2005-12-22 Ecobio, Inc. Testosterone stimulant
RU2309740C1 (ru) 2006-08-03 2007-11-10 Исаак Григорьевич Гитлин Антиоксидант для профилактики заболеваний, связанных с окислительным стрессом, способ его получения, содержащий его гранулят и таблетированная или капсулированная форма на его основе
FR2950252B1 (fr) 2009-09-23 2012-01-20 Centre Nat Rech Scient Forme galenique capable d'adsorber de maniere specifique les molecules indesirables

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE24642E (en) 1959-04-28 Therapeutic preparations of iron
US24642A (en) * 1859-07-05 Joshua i r v ix g
US2755275A (en) * 1952-08-29 1956-07-17 Abbott Lab Process for sulfating chitin
GB746870A (en) * 1952-10-15 1956-03-21 Upjohn Co Preparation of sulphated chitosan
US2893916A (en) * 1956-05-28 1959-07-07 Rubin Martin Iron containing compositions
US2955981A (en) * 1957-12-31 1960-10-11 American Cyanamid Co Prevention of iron-deficiency anemias in suckling mammals
US3102844A (en) * 1960-02-02 1963-09-03 American Cyanamid Co Oral iron-glucosamine hematinic composition and therapy
ES360433A1 (es) * 1968-11-20 1970-11-16 Rocador Sa Procedimiento para la fabricacion de un compuesto de hierrotrivalente apropiado para administracion por via oral.
US3908004A (en) * 1970-05-20 1975-09-23 C L Basingstoke Limited Process for making injectable iron compositions for treating iron-deficiency anemia
JPS6039681B2 (ja) * 1976-01-01 1985-09-07 日本臓器製薬株式会社 デキストリン・クエン酸・第二鉄多核複合体及び該複合体を含有する非経口用鉄剤
ES444380A1 (es) * 1976-01-16 1977-06-16 Gosalvez Mario Un procedimiento para preparar derivados metalicos antraci- clinicos.
US4337335A (en) * 1978-05-18 1982-06-29 Schering Corporation Transition metal salt complexes of polyamino organic compounds
IT1104351B (it) * 1978-06-14 1985-10-21 Muzzarelli Riccardo Il complesso glucano chitosano il metodo della sua produzione a partire da muffe funghi e lieviti e i suoi usi
DE3228231A1 (de) * 1982-07-28 1984-02-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München Arzneimittel, calciummischsalze von polymeren, anionischen carbonsaeuren und/oder schwefelsaeureestern, verfahren zu ihrer herstellung und ihre verwendung
FR2555993B1 (fr) * 1983-12-06 1986-11-07 Anic Spa Chitosanes 6-sulfates et procede pour leur preparation
US4623539A (en) * 1983-02-04 1986-11-18 Tunc Deger C Nutrient barrier polysaccharide compositions and method of use
US4659697A (en) * 1983-05-20 1987-04-21 Kentaro Tanaka Antianaemic composition and a process for producing the same
JPS60142923A (ja) * 1983-12-28 1985-07-29 Lion Corp 歯周病薬

Also Published As

Publication number Publication date
ES552951A0 (es) 1987-05-16
EP0194497A2 (en) 1986-09-17
US4810695A (en) 1989-03-07
IT8519916A0 (it) 1985-03-14
IT1184161B (it) 1987-10-22
EP0194497A3 (en) 1988-03-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203