ES8704921A1 - Un procedimiento para preparar acidos (6,11-dihidro-11-oxodibenz b,c, oxepinil) pentanoicos - Google Patents

Un procedimiento para preparar acidos (6,11-dihidro-11-oxodibenz b,c, oxepinil) pentanoicos

Info

Publication number
ES8704921A1
ES8704921A1 ES551427A ES551427A ES8704921A1 ES 8704921 A1 ES8704921 A1 ES 8704921A1 ES 551427 A ES551427 A ES 551427A ES 551427 A ES551427 A ES 551427A ES 8704921 A1 ES8704921 A1 ES 8704921A1
Authority
ES
Spain
Prior art keywords
oxodibenz
oxepinyl
dihydro
intermediates
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551427A
Other languages
English (en)
Other versions
ES551427A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of ES551427A0 publication Critical patent/ES551427A0/es
Publication of ES8704921A1 publication Critical patent/ES8704921A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Epoxy Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE ACIDOS (6,11-DIHIDRO-11-OXODIBENZB,EOXEPINIL) PENTANOICOS, DE FORMULA GENERAL (I), Y SUS ANTIPODAS OPTICOS Y SUS SALES FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN CICLIZAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE X ES ALQUILO DE 1 A 5 ATOMOS DE CARBONO, ALCOXI DE 1 A 5 ATOMOS DE CARBONO, HALOGENO O TRIFLUOROMETILO; Y M ES 0, 1 O 2, EN PRESENCIA DE UN REACCIONANTE FRIEDEL-CRAFTS. EL COMPUESTO OBTENIDO SE HIDROLIZA Y OPCIONALMENTE SE ESTERIFICA. DE APLICACION EN EL TRATAMIENTO DE LA ARTRITIS.
ES551427A 1984-04-27 1986-01-30 Un procedimiento para preparar acidos (6,11-dihidro-11-oxodibenz b,c, oxepinil) pentanoicos Expired ES8704921A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60467284A 1984-04-27 1984-04-27

Publications (2)

Publication Number Publication Date
ES551427A0 ES551427A0 (es) 1987-04-16
ES8704921A1 true ES8704921A1 (es) 1987-04-16

Family

ID=24420536

Family Applications (2)

Application Number Title Priority Date Filing Date
ES542555A Expired ES8608505A1 (es) 1984-04-27 1985-04-25 Un procedimiento para preparar acidos (6,11-dihidro-11-oxo- dibenz(b,e,)oxepinil)pentanoicos
ES551427A Expired ES8704921A1 (es) 1984-04-27 1986-01-30 Un procedimiento para preparar acidos (6,11-dihidro-11-oxodibenz b,c, oxepinil) pentanoicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES542555A Expired ES8608505A1 (es) 1984-04-27 1985-04-25 Un procedimiento para preparar acidos (6,11-dihidro-11-oxo- dibenz(b,e,)oxepinil)pentanoicos

Country Status (8)

Country Link
EP (1) EP0159684B1 (es)
JP (1) JPS60243082A (es)
AT (1) ATE46692T1 (es)
DE (1) DE3573256D1 (es)
DK (1) DK189285A (es)
ES (2) ES8608505A1 (es)
GR (1) GR851016B (es)
PT (1) PT80359B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5139016B2 (ja) * 2006-10-02 2013-02-06 住友化学株式会社 オキソジベンゾオキセピン酢酸第３級アルキルエステルの製造方法
EP2072507A4 (en) * 2006-10-02 2009-11-04 Sumitomo Chemical Co ALKYL ESTER TERTIARY OF OXODIBENZOXEPINACETIC ACID

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2629569A1 (de) * 1975-07-30 1977-03-31 Hoechst Ag 6,11-dihydro-11-oxodibenz eckige klammer auf b,e eckige klammer zu oxepin-alkansaeuren und deren ester sowie verfahren zu ihrer herstellung
DE2716230A1 (de) * 1976-03-17 1977-10-27 Hoechst Ag Medikament zur behandlung von hautentzuendungen

Also Published As

Publication number Publication date
GR851016B (es) 1985-11-25
ATE46692T1 (de) 1989-10-15
PT80359B (en) 1987-02-11
ES551427A0 (es) 1987-04-16
PT80359A (en) 1985-05-01
ES8608505A1 (es) 1986-06-16
EP0159684A2 (en) 1985-10-30
JPS60243082A (ja) 1985-12-03
ES542555A0 (es) 1986-06-16
EP0159684B1 (en) 1989-09-27
EP0159684A3 (en) 1986-10-08
DE3573256D1 (en) 1989-11-02
DK189285D0 (da) 1985-04-26
DK189285A (da) 1985-10-28

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