ES8703873A1 - Un procedimiento para preparar 2-fenilipirano (2,3-b) piridinas. - Google Patents

Un procedimiento para preparar 2-fenilipirano (2,3-b) piridinas.

Info

Publication number
ES8703873A1
ES8703873A1 ES547983A ES547983A ES8703873A1 ES 8703873 A1 ES8703873 A1 ES 8703873A1 ES 547983 A ES547983 A ES 547983A ES 547983 A ES547983 A ES 547983A ES 8703873 A1 ES8703873 A1 ES 8703873A1
Authority
ES
Spain
Prior art keywords
phenylpyrano
pyridines
pyridyl
phenyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547983A
Other languages
English (en)
Other versions
ES547983A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of ES547983A0 publication Critical patent/ES547983A0/es
Publication of ES8703873A1 publication Critical patent/ES8703873A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR 2-FENILPIRANO2,3-BPIRIDINAS. CONSISTENTE EN CICLAR LOS ALCOHOLES APROPIADOS DE FORMULA GENERAL (II, III), UTILIZANDO COMO REACTIVO PARA DICHA CICLACION, ACIDO BROMHIDRICO Y ACIDO ACETICO CUANDO Q ES -OCH3 Y UNA BASE FUERTE CUANDO Q ES CLORO Y, OPCIONALMENTE, CUANDO LA LINEA DE PUNTOS REPRESENTA UN DOBLE ENLACE EN LA POSICION 3,4 EN EL COMPUESTO OBTENIDO, SOMETER DICHO COMPUESTO A REDUCCION CATALITICA CON HIDROGENO Y NIQUEL RANEY PARA DAR EL CORRESPONDIENTE COMPUESTO SATURADO, DANDO EL COMPUESTO DE FORMULA (I). SIENDO: R, R.. Y RL, HIDROGENO O ALQUILO INFERIOR; X ES HIDROGENO, CLORL, BROMO, ALQUILTIO U OTROS; Y, HIDROGENO, HALO, DI O TRI-CLORO, ALQUILO U OTROS; Y LA LINEA DE PUNTOS INDICA LA PRESENCIA OPCIONAL DE UN DOBLE ENLACE EN LAS POSICIONES 2,3 O 2,4. APLICACION EN MEDICINA FRENTE A VARIOS VIRUS.
ES547983A 1984-10-19 1985-10-17 Un procedimiento para preparar 2-fenilipirano (2,3-b) piridinas. Expired ES8703873A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/663,020 US4588733A (en) 1984-10-19 1984-10-19 2-phenylpyrano[2,3-b]pyridines and their use in inhibiting viruses

Publications (2)

Publication Number Publication Date
ES547983A0 ES547983A0 (es) 1987-03-01
ES8703873A1 true ES8703873A1 (es) 1987-03-01

Family

ID=24660185

Family Applications (2)

Application Number Title Priority Date Filing Date
ES547983A Expired ES8703873A1 (es) 1984-10-19 1985-10-17 Un procedimiento para preparar 2-fenilipirano (2,3-b) piridinas.
ES557062A Expired ES8801283A1 (es) 1984-10-19 1986-09-12 Un procedimiento para preparar 2-finilpirado(2,3-b)piridinas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES557062A Expired ES8801283A1 (es) 1984-10-19 1986-09-12 Un procedimiento para preparar 2-finilpirado(2,3-b)piridinas

Country Status (22)

Country Link
US (1) US4588733A (es)
EP (1) EP0178633B1 (es)
JP (1) JPH064633B2 (es)
KR (1) KR900004214B1 (es)
CN (1) CN1007249B (es)
AR (1) AR242956A1 (es)
AT (1) ATE71379T1 (es)
AU (1) AU576906B2 (es)
CA (1) CA1294282C (es)
DE (1) DE3585128D1 (es)
DK (1) DK161328C (es)
ES (2) ES8703873A1 (es)
FI (1) FI83520C (es)
GR (1) GR852532B (es)
HU (1) HU193350B (es)
IE (1) IE58145B1 (es)
IL (1) IL76776A (es)
NO (1) NO162908C (es)
NZ (1) NZ213814A (es)
PH (1) PH23586A (es)
PT (1) PT81329B (es)
ZA (1) ZA857872B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034531A (en) * 1988-12-23 1991-07-23 Schering Corporation Fused polycyclic pyranyl compounds as antiviral agents
WO1993017682A1 (en) * 1992-03-04 1993-09-16 Abbott Laboratories Angiotensin ii receptor antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3518273A (en) * 1966-08-03 1970-06-30 Warner Lambert Pharmaceutical Benzopyranquinolinol derivatives and process for their production
EP0004579B1 (en) * 1978-03-15 1982-08-18 The Wellcome Foundation Limited Flavans, process for their preparation and pharmaceutical compositions containing them
US4563468A (en) * 1979-09-13 1986-01-07 Burroughs Wellcome Co. Chemotherapeutic agents
US4801593A (en) * 1979-09-13 1989-01-31 Burroughs Wellcome Co. Chemotherapeutic agents
JPS5651470A (en) * 1979-09-13 1981-05-09 Wellcome Found Flavan derivative
US4371537A (en) * 1981-08-13 1983-02-01 The Dow Chemical Company Sulfur-substituted phenoxypyridines having antiviral activity

Also Published As

Publication number Publication date
EP0178633A2 (en) 1986-04-23
HUT38946A (en) 1986-07-28
IL76776A (en) 1989-08-15
IE58145B1 (en) 1993-07-14
ES8801283A1 (es) 1988-01-01
EP0178633B1 (en) 1992-01-08
AU576906B2 (en) 1988-09-08
KR860003261A (ko) 1986-05-21
CN85109303A (zh) 1986-08-20
NO162908C (no) 1990-03-07
FI854026A0 (fi) 1985-10-16
DK161328B (da) 1991-06-24
IE852590L (en) 1986-04-19
EP0178633A3 (en) 1988-06-22
DE3585128D1 (de) 1992-02-20
AU4858885A (en) 1986-04-24
HU193350B (en) 1987-09-28
ES557062A0 (es) 1988-01-01
US4588733A (en) 1986-05-13
ES547983A0 (es) 1987-03-01
FI83520C (fi) 1991-07-25
DK478685A (da) 1986-04-20
JPH064633B2 (ja) 1994-01-19
PT81329B (pt) 1987-10-20
NO854110L (no) 1986-04-21
JPS61112079A (ja) 1986-05-30
GR852532B (es) 1986-02-19
PH23586A (en) 1989-09-11
ZA857872B (en) 1986-05-28
NZ213814A (en) 1988-05-30
FI83520B (fi) 1991-04-15
ATE71379T1 (de) 1992-01-15
DK161328C (da) 1991-12-09
CA1294282C (en) 1992-01-14
KR900004214B1 (ko) 1990-06-18
CN1007249B (zh) 1990-03-21
PT81329A (en) 1985-11-01
NO162908B (no) 1989-11-27
IL76776A0 (en) 1986-02-28
AR242956A1 (es) 1993-06-30
DK478685D0 (da) 1985-10-18
FI854026L (fi) 1986-04-20

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