ES8701228A1 - Un metodo para producir una propioxantina - Google Patents
Un metodo para producir una propioxantinaInfo
- Publication number
- ES8701228A1 ES8701228A1 ES547630A ES547630A ES8701228A1 ES 8701228 A1 ES8701228 A1 ES 8701228A1 ES 547630 A ES547630 A ES 547630A ES 547630 A ES547630 A ES 547630A ES 8701228 A1 ES8701228 A1 ES 8701228A1
- Authority
- ES
- Spain
- Prior art keywords
- enkephalinase
- inhibitors
- preparation
- same
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE PROPIOXATINA, DE FORMULA (I), Y DE SUS SALES. COMPRENDE EL CULTIVO DE UN ORGANISMO PRODUCTOR DE PROPIOXATINA, DEL GENERO KITASATOSPORIA EN UN MEDIO DE CULTIVO AGITADO O SUMERGIDO, QUE CONTIENE FUENTES NUTRIENTES DE CARBONO Y DE NITROGENO Y SALES INORGANICAS, A UN PH ENTRE 5,5 Y 8,0 Y A UNA TEMPERATURA COMPRENDIDA ENTRE 6JC Y 38JC. SEPARACION DE LAS PROPIOXATINAS DEL MEDIO DE CULTIVO Y PURIFICACION DE LAS MISMAS SIGUIENDO TECNICAS CONVENCIONALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD COMO ANALGESICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59208789A JPS6188884A (ja) | 1984-10-04 | 1984-10-04 | エンケフアリナ−ゼb阻害物質およびその製法 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES547630A0 ES547630A0 (es) | 1986-11-16 |
ES8701228A1 true ES8701228A1 (es) | 1986-11-16 |
Family
ID=16562134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES547630A Expired ES8701228A1 (es) | 1984-10-04 | 1985-10-04 | Un metodo para producir una propioxantina |
Country Status (7)
Country | Link |
---|---|
US (1) | US4804676A (es) |
EP (1) | EP0177366B1 (es) |
JP (1) | JPS6188884A (es) |
AT (1) | ATE84045T1 (es) |
CA (1) | CA1277623C (es) |
DE (1) | DE3586935T2 (es) |
ES (1) | ES8701228A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2746372B2 (ja) * | 1988-03-11 | 1998-05-06 | 科研製薬株式会社 | F−0368物質 |
US6939855B2 (en) | 1997-07-31 | 2005-09-06 | Elan Pharmaceuticals, Inc. | Anti-inflammatory compositions and method |
US7030114B1 (en) | 1997-07-31 | 2006-04-18 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US6492421B1 (en) | 1997-07-31 | 2002-12-10 | Athena Neurosciences, Inc. | Substituted phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US6362341B1 (en) | 1997-07-31 | 2002-03-26 | Athena Neurosciences, Inc. | Benzyl compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US6423688B1 (en) * | 1997-07-31 | 2002-07-23 | Athena Neurosciences, Inc. | Dipeptide and related compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US6559127B1 (en) | 1997-07-31 | 2003-05-06 | Athena Neurosciences, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US6583139B1 (en) * | 1997-07-31 | 2003-06-24 | Eugene D. Thorsett | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US6797820B2 (en) | 1999-12-17 | 2004-09-28 | Vicuron Pharmaceuticals Inc. | Succinate compounds, compositions and methods of use and preparation |
AU2268401A (en) * | 1999-12-17 | 2001-06-25 | Versicor Inc | Novel succinate compounds, compositions and methods of use and preparation |
US20040006093A1 (en) * | 2000-10-17 | 2004-01-08 | Thorsett Eugene D. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
ATE360014T1 (de) * | 2001-06-15 | 2007-05-15 | Vicuron Pharm Inc | Bicyclische pyrrolidinverbindungen |
AR036053A1 (es) * | 2001-06-15 | 2004-08-04 | Versicor Inc | Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas |
GB0509223D0 (en) | 2005-05-05 | 2005-06-15 | Chroma Therapeutics Ltd | Enzyme inhibitors |
CH713803B1 (de) | 2016-04-21 | 2023-08-15 | 4TEEN4 Pharmaceuticals GmbH | Verfahren zur Diagnose durch Bestimmung von DPP3, Hemmer der Aktivität von DPP3 und Zusammensetzung mit einem Hemmer. |
WO2019081595A2 (en) | 2017-10-25 | 2019-05-02 | Sphingotec Therapeutics Gmbh | DPP3 BINDER DIRECTED TO AND BINDING SPECIFIC DPP3 EPITOPES AND USE THEREOF IN THE PREVENTION OR TREATMENT OF OXIDATIVE STRESS ASSOCIATED DISEASES / CONDITIONS |
EP4121763A1 (en) | 2020-03-16 | 2023-01-25 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 in patients infected with coronavirus |
EP3922993A1 (en) | 2020-06-12 | 2021-12-15 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 in patients infected with coronavirus |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4284561A (en) * | 1979-12-03 | 1981-08-18 | E. R. Squibb & Sons, Inc. | Hydroxamic acid derivatives of mercaptoacyl amino acids |
JPS5697266A (en) * | 1979-12-28 | 1981-08-05 | Tanabe Seiyaku Co Ltd | Proline derivative and its preparation |
JPS56139455A (en) * | 1980-04-02 | 1981-10-30 | Santen Pharmaceut Co Ltd | Sulfur-containing acylaminoacid |
FR2518088B1 (fr) * | 1981-12-16 | 1987-11-27 | Roques Bernard | Nouveaux derives d'aminoacides, et leur application therapeutique |
JPS6115840A (ja) * | 1984-07-03 | 1986-01-23 | Microbial Chem Res Found | 免疫賦活剤 |
-
1984
- 1984-10-04 JP JP59208789A patent/JPS6188884A/ja active Granted
-
1985
- 1985-10-01 US US06/782,524 patent/US4804676A/en not_active Expired - Fee Related
- 1985-10-04 AT AT85307127T patent/ATE84045T1/de not_active IP Right Cessation
- 1985-10-04 CA CA000492328A patent/CA1277623C/en not_active Expired - Fee Related
- 1985-10-04 EP EP85307127A patent/EP0177366B1/en not_active Expired - Lifetime
- 1985-10-04 DE DE8585307127T patent/DE3586935T2/de not_active Expired - Fee Related
- 1985-10-04 ES ES547630A patent/ES8701228A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
US4804676A (en) | 1989-02-14 |
EP0177366B1 (en) | 1992-12-30 |
DE3586935T2 (de) | 1993-07-22 |
JPH0413358B2 (es) | 1992-03-09 |
ATE84045T1 (de) | 1993-01-15 |
CA1277623C (en) | 1990-12-11 |
JPS6188884A (ja) | 1986-05-07 |
DE3586935D1 (de) | 1993-02-11 |
ES547630A0 (es) | 1986-11-16 |
EP0177366A2 (en) | 1986-04-09 |
EP0177366A3 (en) | 1988-08-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970519 |