ES8701167A1 - Un procedimiento para preparar una quinolona - Google Patents

Un procedimiento para preparar una quinolona

Info

Publication number
ES8701167A1
ES8701167A1 ES535273A ES535273A ES8701167A1 ES 8701167 A1 ES8701167 A1 ES 8701167A1 ES 535273 A ES535273 A ES 535273A ES 535273 A ES535273 A ES 535273A ES 8701167 A1 ES8701167 A1 ES 8701167A1
Authority
ES
Spain
Prior art keywords
lower alkyl
hydrogen
lower alkoxy
quinolones
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535273A
Other languages
English (en)
Other versions
ES535273A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838322470A external-priority patent/GB8322470D0/en
Priority claimed from GB848413535A external-priority patent/GB8413535D0/en
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of ES8701167A1 publication Critical patent/ES8701167A1/es
Publication of ES535273A0 publication Critical patent/ES535273A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PREPARACION DE DERIVADOS DE QUINOLONA, DE FORMULA GENERAL (I), DONDE R ES 1-METILO O UN 2-ALQUILO DE 1-4C; R1 ES UN ALQUILO DE 1-4C; R2 ES H, HALO, ALQUILO DE 1-4C, ALCOXI DE 1-4C, TRIFLUOROMETILO, CIANO, DIFLUOROMETOXI, ALQUILSULFINILO DE 1-4C, FENILSULFINILO O -NR4R5 O N-OXIDO, DONDE R4 Y R5, QUE PUEDEN SER IGUALES O DIFERENTES, SON ALQUILO DE 1-4C O JUNTO CON EL N FORMAN UN RADICAL PIRROLIDINO, PIPERIDINO O MORFOLINO Y R3 ES H, F, ALQUILO DE 1-4C O ALCOXI DE 1-4C Y CUANDO R3 ES ALCOXI DE 1-4C R 2 NO LO ES. LOS COMPUESTOS SE PREPARAR POR ALCOHILACION DE UN COMPUESTO DE FORMULA (II), DONDE R ES H, 1-METILO O 2-ALQUILO DE 1-4C Y R2 Y R3 LOS MISMOS ANTES DEFINIDOS, CON UN AGENTE ALCOHILANTE, POR EJEMPLO SULFATO P HALOGENURO DE ALCOHILO Y LOS COMPUESTOS DE FORMULA (II) SE PREPARAN A PARTIR DE LOS DE FORMULA (III), DONDE R, R1 Y R2 SE DEFINEN COMO ANTES, POR REACCION CON UN ORTOFORMIATO DE TRIALQUILO INFERIOR.
ES535273A 1983-08-20 1984-08-17 Un procedimiento para preparar una quinolona Expired ES8701167A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838322470A GB8322470D0 (en) 1983-08-20 1983-08-20 Therapeutic agents
GB848413535A GB8413535D0 (en) 1984-05-25 1984-05-25 Therapeutic agents

Publications (2)

Publication Number Publication Date
ES8701167A1 true ES8701167A1 (es) 1986-11-16
ES535273A0 ES535273A0 (es) 1986-11-16

Family

ID=26286783

Family Applications (3)

Application Number Title Priority Date Filing Date
ES535273A Expired ES8701167A1 (es) 1983-08-20 1984-08-17 Un procedimiento para preparar una quinolona
ES545834A Expired ES8607279A1 (es) 1983-08-20 1985-08-01 Un procedimiento para preparar una quinolona
ES545835A Expired ES8607280A1 (es) 1983-08-20 1985-08-01 Un procedimiento para preparar una quinolona

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES545834A Expired ES8607279A1 (es) 1983-08-20 1985-08-01 Un procedimiento para preparar una quinolona
ES545835A Expired ES8607280A1 (es) 1983-08-20 1985-08-01 Un procedimiento para preparar una quinolona

Country Status (19)

Country Link
US (1) US4659718A (es)
EP (1) EP0135367B1 (es)
AU (1) AU572177B2 (es)
CA (1) CA1244420A (es)
CS (1) CS248720B2 (es)
DD (1) DD223451A5 (es)
DE (1) DE3469898D1 (es)
DK (1) DK395084A (es)
ES (3) ES8701167A1 (es)
FI (1) FI843266A (es)
GB (1) GB2147581B (es)
GR (1) GR80122B (es)
HU (1) HUT35665A (es)
JO (1) JO1330B1 (es)
NO (1) NO843292L (es)
NZ (1) NZ209193A (es)
PT (1) PT79031B (es)
RO (1) RO89124A (es)
ZW (1) ZW13484A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8608874A1 (es) * 1984-05-29 1986-09-01 Pfizer Un procedimiento para la preparacion de una 2-(1h)-quinolona
DE3576686D1 (de) * 1984-08-15 1990-04-26 Boots Co Ltd Chinolinone, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen praeparate.
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8529362D0 (en) * 1985-11-28 1986-01-02 Pfizer Ltd Quinolone cardiac stimulants
GB8627698D0 (en) * 1986-11-20 1986-12-17 Boots Co Plc Therapeutic agents
GB8804016D0 (en) * 1988-02-22 1988-03-23 Boots Co Plc Therapeutic agents
GB9026389D0 (en) * 1990-12-05 1991-01-23 Merck Sharp & Dohme Therapeutic agents
US9107414B2 (en) 2012-01-11 2015-08-18 Bayer Cropscience Ag Tetrazol-5-yl- and triazol-5-yl-aryl compounds and use thereof as herbicides
WO2015052178A1 (en) 2013-10-10 2015-04-16 Basf Se 1,2,5-oxadiazole compounds and their use as herbicides
WO2015052173A1 (en) 2013-10-10 2015-04-16 Basf Se Tetrazole and triazole compounds and their use as herbicides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50106975A (es) * 1974-02-01 1975-08-22
US4035368A (en) * 1975-04-02 1977-07-12 Riker Laboratories, Inc. Substituted 3-(1H-tetrazol-5-yl)-quinoline compounds
US4474787A (en) * 1977-05-04 1984-10-02 Fisons Limited 7,6 Dioxo-4H,6H-pyrano[3,2-g]quinoline dicarboxylic acids and anti-allergic use thereof
US4259437A (en) * 1978-09-18 1981-03-31 Ciba-Geigy Ag Development inhibitor releasing compounds and their use in photographic materials
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
EP0104018A3 (en) * 1982-09-21 1985-06-26 FISONS plc Benzopyran, benzothiapyran and quinoline compounds and pharmaceutical compositions containing them
US4735948A (en) * 1983-03-25 1988-04-05 Merrell Dow Pharmaceuticals Inc. (1H-tetrazol-5-yl)-2(1H)-quinolinones and-naphthyridones and antiallergic use thereof

Also Published As

Publication number Publication date
ES545835A0 (es) 1986-05-16
EP0135367B1 (en) 1988-03-16
DK395084D0 (da) 1984-08-17
US4659718A (en) 1987-04-21
DD223451A5 (de) 1985-06-12
GB8420686D0 (en) 1984-09-19
FI843266A0 (fi) 1984-08-17
GB2147581A (en) 1985-05-15
NO843292L (no) 1985-02-21
AU572177B2 (en) 1988-05-05
ES8607280A1 (es) 1986-05-16
GB2147581B (en) 1987-04-01
ES545834A0 (es) 1986-05-16
DE3469898D1 (en) 1988-04-21
CS248720B2 (en) 1987-02-12
ES8607279A1 (es) 1986-05-16
NZ209193A (en) 1987-04-30
AU3166784A (en) 1985-02-21
HUT35665A (en) 1985-07-29
FI843266A (fi) 1985-02-21
GR80122B (en) 1984-12-13
RO89124A (ro) 1986-04-30
EP0135367A1 (en) 1985-03-27
PT79031B (en) 1986-08-22
JO1330B1 (en) 1986-11-30
PT79031A (en) 1984-09-01
CA1244420A (en) 1988-11-08
ZW13484A1 (en) 1985-03-13
ES535273A0 (es) 1986-11-16
DK395084A (da) 1985-02-21

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