ES8700056A1 - Procedimiento de producir antigenos relacionados con el enlace glicosidico derivados de cancer. - Google Patents
Procedimiento de producir antigenos relacionados con el enlace glicosidico derivados de cancer.Info
- Publication number
- ES8700056A1 ES8700056A1 ES544306A ES544306A ES8700056A1 ES 8700056 A1 ES8700056 A1 ES 8700056A1 ES 544306 A ES544306 A ES 544306A ES 544306 A ES544306 A ES 544306A ES 8700056 A1 ES8700056 A1 ES 8700056A1
- Authority
- ES
- Spain
- Prior art keywords
- same
- related antigen
- binding
- glycosidic linkage
- thermally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000427 antigen Substances 0.000 title abstract 5
- 102000036639 antigens Human genes 0.000 title abstract 5
- 108091007433 antigens Proteins 0.000 title abstract 5
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- 102000018656 Mitogen Receptors Human genes 0.000 abstract 4
- 108010052006 Mitogen Receptors Proteins 0.000 abstract 4
- 210000000170 cell membrane Anatomy 0.000 abstract 4
- 210000004027 cell Anatomy 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 102000004856 Lectins Human genes 0.000 abstract 1
- 108090001090 Lectins Proteins 0.000 abstract 1
- OVRNDRQMDRJTHS-CBQIKETKSA-N N-Acetyl-D-Galactosamine Chemical compound CC(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@H](O)[C@@H]1O OVRNDRQMDRJTHS-CBQIKETKSA-N 0.000 abstract 1
- MBLBDJOUHNCFQT-UHFFFAOYSA-N N-acetyl-D-galactosamine Natural products CC(=O)NC(C=O)C(O)C(O)C(O)CO MBLBDJOUHNCFQT-UHFFFAOYSA-N 0.000 abstract 1
- 125000000837 carbohydrate group Chemical group 0.000 abstract 1
- 239000002523 lectin Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ANTIGENOS RELACIONADOS CON EL ENLACE GLICOSIDICO DERIVADOS DE CELULAS DE CANCER, QUE SON UNA GLICOPROTEINA CON UNA ESTRUCTURA TERMINAL SACARIDICA DE GALACTOSA O N-ACETILGALACTOSAMINA. COMPRENDE LA HOMOGENEIZACION DE CELULAS CANCEROSAS CULTIVADAS, HUMANAS O ANIMALES, ESPONTANEAS, PROVOCADAS QUIMICA O VIRALMENTE, U ORIGINADAS EN TEJIDOS SOMETIDOS A INTERVENCIONES QUIRURGICAS, EN DISOLUCION SALINA FISIOLOGICA; SEPARACION DEL PRECIPITADO POR CENTRIFUGACION, SOLUBILIZACION DEL MISMO CON UN AGENTE TENSIOACTIVO Y RECOGIDA DEL SOBRENADANTE QUE RESULTA. REACCION DEL LIQUIDO SOBRENADANTE CON UN ANTICUERPO DE ANTIGENO QUE DERIVA DE CELULAS DE CANCER, POR MEDIOS FISIOCOQUIMICOS O BIOQUIMICOS CONVENCIONALES, PARA ENLAZAR UN GLICOPROTEINA Y, FINALMENTE, RECOGER DICHA GLICOPROTEINA. ESTOS ANTIGENOS TIENEN APLICACIONES PARA TRATAMIENTO Y PREVENCION DE CANCERES.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57177411A JPS5967224A (ja) | 1982-10-08 | 1982-10-08 | 糖鎖関連抗原およびその製造法ならびにこれを有効成分とする抗癌剤 |
| JP58100528A JPS59225119A (ja) | 1983-06-06 | 1983-06-06 | 熱変性抗原の製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8700056A1 true ES8700056A1 (es) | 1986-10-16 |
| ES544306A0 ES544306A0 (es) | 1986-10-16 |
Family
ID=26441535
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES526622A Expired ES8600692A1 (es) | 1982-10-08 | 1983-10-07 | Procedimiento de producir antigenos y sus intermedios |
| ES544306A Expired ES8700056A1 (es) | 1982-10-08 | 1985-05-30 | Procedimiento de producir antigenos relacionados con el enlace glicosidico derivados de cancer. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES526622A Expired ES8600692A1 (es) | 1982-10-08 | 1983-10-07 | Procedimiento de producir antigenos y sus intermedios |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0106285A3 (es) |
| CA (1) | CA1236016A (es) |
| DK (1) | DK463283A (es) |
| ES (2) | ES8600692A1 (es) |
| FI (1) | FI80711C (es) |
| NO (1) | NO833655L (es) |
| PH (1) | PH23701A (es) |
| PT (1) | PT77472B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60214737A (ja) * | 1984-04-06 | 1985-10-28 | Nippon Koutai Kenkyusho:Kk | 糖鎖関連抗原の製造法 |
| SE468231B (sv) * | 1984-05-18 | 1992-11-23 | Kabi Pharmacia Ab | Foerfarande foer att paavisa smaacelligt lungcarcinomantigen och anvaendning av antikroppar mot fukosylsialosylgangliotetraos foer framstaellning av komposition foer behandling eller in vivo/ diagnos |
| JPH03263401A (ja) * | 1990-03-13 | 1991-11-22 | Nippon Koutai Kenkyusho:Kk | 新規糖鎖 |
| MD838G2 (ro) * | 1992-07-21 | 1998-09-30 | Alexandr Nicolaenco | Remediu biologic activ cu proprietate imunomodulatoare, procedeu de obţinere a lui, preparat pe baza lui şi procedeu de normalizare a stării fiziologice a omului şi animalelor |
| US5376531A (en) * | 1992-09-03 | 1994-12-27 | Northwestern University | Method of detecting cancer |
| DK140992D0 (da) * | 1992-11-24 | 1992-11-24 | Ole Buchardt | Fremgangsmaade til frembringelse af antistoffer mod haptener og andre b-celle-antigener, antistoffer opnaaet ved fremgangsmaaden og anvendelse af disse antistoffer til fremstilling af vacciner, isaer til veterinaermedicinsk brug |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2112643B (en) * | 1981-05-19 | 1984-08-30 | Stephen Sugaar | Strongly antigenic tumor specific substances and methods for detecting cancer using said substances |
| GB2106935B (en) * | 1981-10-01 | 1985-01-30 | Otsuka Pharma Co Ltd | Cancer cell-combatting lymphocytes process for the production thereof and anticancer agents containing said lymphocytes |
| GB2121417A (en) * | 1982-02-22 | 1983-12-21 | Carlton Med Prod | Antigens and antibodies useful in the detection of cancer |
-
1983
- 1983-10-07 NO NO833655A patent/NO833655L/no unknown
- 1983-10-07 DK DK463283A patent/DK463283A/da not_active Application Discontinuation
- 1983-10-07 CA CA000438680A patent/CA1236016A/en not_active Expired
- 1983-10-07 FI FI833652A patent/FI80711C/fi not_active IP Right Cessation
- 1983-10-07 EP EP83110040A patent/EP0106285A3/en not_active Withdrawn
- 1983-10-07 PT PT77472A patent/PT77472B/pt not_active IP Right Cessation
- 1983-10-07 ES ES526622A patent/ES8600692A1/es not_active Expired
- 1983-10-07 PH PH29673A patent/PH23701A/en unknown
-
1985
- 1985-05-30 ES ES544306A patent/ES8700056A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0106285A2 (en) | 1984-04-25 |
| FI833652A (fi) | 1984-04-09 |
| CA1236016A (en) | 1988-05-03 |
| PH23701A (en) | 1989-09-27 |
| DK463283A (da) | 1984-04-09 |
| ES526622A0 (es) | 1985-11-01 |
| FI80711C (fi) | 1990-07-10 |
| NO833655L (no) | 1984-04-09 |
| PT77472A (en) | 1983-11-01 |
| ES8600692A1 (es) | 1985-11-01 |
| DK463283D0 (da) | 1983-10-07 |
| FI80711B (fi) | 1990-03-30 |
| EP0106285A3 (en) | 1987-09-02 |
| FI833652A0 (fi) | 1983-10-07 |
| PT77472B (en) | 1986-02-12 |
| ES544306A0 (es) | 1986-10-16 |
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