ES8606371A1 - Derivados de carboxiamidas n-glicosiladas como medios en la lucha contra las enfermedades de tipo reumatico. - Google Patents
Derivados de carboxiamidas n-glicosiladas como medios en la lucha contra las enfermedades de tipo reumatico.Info
- Publication number
- ES8606371A1 ES8606371A1 ES539104A ES539104A ES8606371A1 ES 8606371 A1 ES8606371 A1 ES 8606371A1 ES 539104 A ES539104 A ES 539104A ES 539104 A ES539104 A ES 539104A ES 8606371 A1 ES8606371 A1 ES 8606371A1
- Authority
- ES
- Spain
- Prior art keywords
- atoms
- glycosylated
- amides
- derivatives
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE CARBOXIAMIDAS N-GLICOSILADAS, DE FORMULA (I), EN LA QUE Z REPRESENTA UN RESTO GLICOSILO ENLAZADO A TRAVES DEL ATOMO DE CARBONO ANOMERO; Y R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES; COMPUESTOS QUE TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES DE TIPO REUMATICO. CONSISTE EN LA REACCION DE LOS AZUCARES INDICADOS POR Z EN LA FORMULA (I), EN FORMA LIBRE O PROTEGIDA, O DERIVADOS ACTIVADOS DE LOS MISMOS, CON UN AMINOCOMPUESTO DE FORMULA R2-NH2, EN LA QUE R2 TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) EN FORMA LIBRE O DE SAL DE ADICION DE ACIDO; SEGUIDA DE LA ACILACION DE LA GLICOSILAMINA ASI OBTENIDA CON UN DERIVADO DEL ACIDO CARBONICO ACTIVADO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833347522 DE3347522A1 (de) | 1983-12-30 | 1983-12-30 | N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8606371A1 true ES8606371A1 (es) | 1986-04-16 |
ES539104A0 ES539104A0 (es) | 1986-04-16 |
Family
ID=6218416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES539104A Expired ES8606371A1 (es) | 1983-12-30 | 1984-12-27 | Derivados de carboxiamidas n-glicosiladas como medios en la lucha contra las enfermedades de tipo reumatico. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4710491A (es) |
EP (1) | EP0147777A3 (es) |
JP (1) | JPS60208992A (es) |
DE (1) | DE3347522A1 (es) |
ES (1) | ES8606371A1 (es) |
ZA (1) | ZA8410111B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3339694A1 (de) * | 1983-11-03 | 1985-05-15 | Bayer Ag, 5090 Leverkusen | Verwendung n-glycosilierter carbonsaeureamid-derivate als wachstumsfoerderer in der tierernaehrung |
DE3403495A1 (de) * | 1983-11-23 | 1985-05-30 | Bayer Ag, 5090 Leverkusen | Phosphorylierte glycosylamide, -harnstoffe, -carbamate und -thiocarbamate, verfahren zu ihrer herstellung sowie ihre verwendung |
DE3347522A1 (de) * | 1983-12-30 | 1985-07-11 | Troponwerke GmbH & Co KG, 5000 Köln | N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises |
DE3410238A1 (de) * | 1984-03-21 | 1985-10-03 | Bayer Ag, 5090 Leverkusen | Glycolipid-aehnliche substanzen in liposomenform |
DE3508025A1 (de) * | 1985-03-07 | 1986-09-11 | Bayer Ag, 5090 Leverkusen | Substituierte o-sulfonyl-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE3611168C2 (de) * | 1985-04-02 | 1994-01-20 | Asahi Chemical Ind | Hydroxybenzoesäurephenylester, deren Herstellung und deren Verwendung als physiologisch wirksame Substanzen |
DE3604681A1 (de) * | 1986-02-14 | 1987-08-20 | Bayer Ag | Neue n-glycosylamidderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
JPS62273919A (ja) * | 1986-05-21 | 1987-11-28 | Takahiro Ochi | 抗リウマチ剤 |
DE3812681A1 (de) * | 1988-04-16 | 1989-11-02 | Bayer Ag | Substituierte n-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
AU638146B2 (en) * | 1990-06-27 | 1993-06-17 | Dainippon Ink And Chemicals Inc. | Alkylated oligosaccharides and acetyl derivatives of the same |
FR2676739B1 (fr) * | 1991-05-22 | 1996-10-11 | Stepan Europe | N-alkyl, n-acetylosylamines, leur procede de preparation et leurs utilisations notamment en tant qu'agents tensioactifs ou agents de solubilisation pour l'isolement de proteines membranaires. |
US5362480A (en) * | 1991-12-31 | 1994-11-08 | Lever Brothers Company, Division Of Conopco, Inc. | Oral hygiene compositions containing amino sugars as antiplaque agents |
US5631245A (en) * | 1995-06-06 | 1997-05-20 | Biodynamics Pharmaceuticals, Inc. | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions |
US6290971B1 (en) * | 1995-06-15 | 2001-09-18 | Aventis Pasteur Limited | Adjuvant compositions comprising a mineral salt and another immunostimulating compound |
FR2760752A1 (fr) * | 1997-03-14 | 1998-09-18 | Inst Francais Du Petrole | Composes chiraux, leur synthese et leur utilisation en support |
US5872111A (en) * | 1997-05-19 | 1999-02-16 | Lever Brothers Company, Division Of Conopco, Inc. | Compositions comprising glycosylamide surfactants |
CA2317305A1 (en) | 2000-08-29 | 2002-02-28 | Tassos P. Anastassiades | Method of enhancing chondrocyte cell growth and glycosaminoglycan production |
AUPS143402A0 (en) * | 2002-03-28 | 2002-05-09 | Alchemia Pty Ltd | Anomeric derivatives of monosaccharides |
ITMI20031311A1 (it) * | 2003-06-27 | 2004-12-28 | Indena Spa | Formulazioni per il trattamento di disturbi artrosici. |
US20050008699A1 (en) * | 2003-07-11 | 2005-01-13 | Fred Wehling | Effervescent glucosamine composition |
CA2479632C (en) * | 2004-08-31 | 2011-07-26 | Tassos Anastassiades | Method for increasing the bone mineral density of a mammal using n-acylated glucosamines |
CN105399783B (zh) * | 2015-11-10 | 2019-03-08 | 江苏苏博特新材料股份有限公司 | 糖胺类有机钢筋阻锈剂及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3213650A1 (de) * | 1982-04-14 | 1983-10-27 | Bayer Ag, 5090 Leverkusen | N-glycosylierte carbonsaeureamid-derivate, verfahren zu ihrer herstellung sowie ihre verwendung zur beeinflussung der koerpereigenen abwehr |
DE3347522A1 (de) * | 1983-12-30 | 1985-07-11 | Troponwerke GmbH & Co KG, 5000 Köln | N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises |
-
1983
- 1983-12-30 DE DE19833347522 patent/DE3347522A1/de not_active Withdrawn
-
1984
- 1984-12-14 US US06/681,965 patent/US4710491A/en not_active Expired - Fee Related
- 1984-12-19 EP EP84115773A patent/EP0147777A3/de not_active Withdrawn
- 1984-12-27 ES ES539104A patent/ES8606371A1/es not_active Expired
- 1984-12-28 ZA ZA8410111A patent/ZA8410111B/xx unknown
- 1984-12-28 JP JP59274975A patent/JPS60208992A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0147777A2 (de) | 1985-07-10 |
EP0147777A3 (de) | 1987-03-25 |
DE3347522A1 (de) | 1985-07-11 |
US4710491A (en) | 1987-12-01 |
JPS60208992A (ja) | 1985-10-21 |
ES539104A0 (es) | 1986-04-16 |
ZA8410111B (en) | 1985-08-28 |
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